Search results for "hate"
showing 10 items of 2099 documents
Decipher the mechanisms of protein conformational changes induced by nucleotide binding through free-energy landscape analysis: ATP binding to Hsp70.
2013
ATP regulates the function of many proteins in the cell by transducing its binding and hydrolysis energies into protein conformational changes by mechanisms which are challenging to identify at the atomic scale. Based on molecular dynamics (MD) simulations, a method is proposed to analyze the structural changes induced by ATP binding to a protein by computing the effective free-energy landscape (FEL) of a subset of its coordinates along its amino-acid sequence. The method is applied to characterize the mechanism by which the binding of ATP to the nucleotide-binding domain (NBD) of Hsp70 propagates a signal to its substrate-binding domain (SBD). Unbiased MD simulations were performed for Hsp…
P-recovery in a pilot-scale struvite crystallisation reactor for source separated urine systems using seawater and magnesium chloride as magnesium so…
2019
[EN] Practical recovery of a non-renewable nutrient, such as phosphorus (P), is essential to support modern agriculture in the near future. The high P content of urine, makes it an attractive source for practicing the recovery of this crucial nutrient. This paper presents the experimental results at pilot-plant scale of struvite crystallisation from a source-separated urine stream using two different magnesium sources, namely magnesium chloride and seawater. The latter was chosen as sustainable option to perform P-recovery in coastal areas. Real seawater was used to assess in a more realistic way its efficiency to precipitate P as struvite, since its composition (with noticeable concentrati…
Ecological restoration in contaminated soils of Kokdzhon phosphate mining area (Zhambyl region, Kazakhstan)
2016
Abstract This study provides results of an ecological restoration activity performed in the Kokdzhon phosphate mining of the Zhambyl region (a semi-desert mining area of Kazakhstan). The test area was made by a quarry-hole, about 1.25 hectares wide, that was preliminarily filled with the earthy material of a dump and, subsequently, levelled. The total volume of human transported material (HTM) used was 700 tonnes. Soil samples were taken from 0 to 30 cm depth at 23 sampling sites and several soil quality parameters were determined. In the test area 750 tree species were planted in suitable dug holes: (150 seedlings of Russian Olive; 150 seedlings of Black Saxaul); 150 seedlings of Androsov …
Correlation between Regional Atp and Blood Flow in Tumors and Surrounding Normal Tissue
1994
Various experimental and human tumors are characterized by a marked heterogeneity in the pathophysiologic micromilieu (1, 2). An inadequate and heterogeneous nutritional blood supply has been suggested to explain the non-uniform distribution of oxygen, pH, and high energy phosphates as it has been observed by many investigators (3, 4). Although there is a distinct understanding of the general interrelationships between these parameters (5), little is known about their actual regional correlation, which cannot be assessed by global measurements. With the autoradiographic method for measurement of blood flow (6, 7) and the metabolic imaging with ATP-induced bioluminescence (8, 9) it has becom…
Conditioning metallic aluminum in magnesium phosphate cements
2016
This work deals with the stabilization / solidification of radioactive waste using cement.More particularly, it aims at assessing the chemical compatibility between metallic aluminum and mortars based on magnesium phosphate cement. The physical and chemical processes leading to setting and hardening of the cement are first investigated. X-ray diffraction (XRD), thermogravimetry (TGA) and nuclear magnetic resonance spectroscopy (31P and11B MAS-NMR) arefirst used to characterize the solid phases formed during hydration, while inductively coupled plasma atomic emission spectroscopy analysis (ICP-AES), electrical conductimetry and pH measurementsprovide information on the pore solution composit…
Effects of high-pressure on the structural, vibrational, and electronic properties of monazite-type PbCrO4
2012
We have performed an experimental study of the crystal structure, lattice dynamics, and optical properties of PbCrO 4 (the mineral crocoite) at ambient and high pressures. In particular, the crystal structure, Raman-active phonons, and electronic band gap have been accurately determined. X-ray-diffraction, Raman, and optical absorption experiments have allowed us also to completely characterize two pressure-induced structural phase transitions. The first transition is from a monoclinic structure to another monoclinic structure. It maintains the symmetry of the crystal but has important consequences in the physical properties; among others, a band-gap collapse is induced. The second one invo…
Assessment of the ecotoxicity of phytotreatment substrate soil as landfill cover material for in-situ leachate management
2019
Phytotreatment capping in closed landfills is a promising, cost-effective, in situ option for sustainable leachate treatment and might be synergistically coupled with energy crops to produce renewable energy (e.g.: biodiesel or bioethanol). This study proposes to use 0.30 m of soil as growing substrate for plants cultivated on the temporary cover of closed landfills. Once the leachate phytotreatment process is no longer required, 0.70 m of the same soil would be added to attain the final top cover configuration. This solution would entail saving the costs of excavation and backfilling. However, worsening of the initial soil quality due to potential contaminant transfer from the liquid to th…
Two-Stage Anaerobic Digestion of Energy Crops: Methane Production, Nitrogen Mineralisation and Heavy Metal Mobilisation
2006
Energy crops (willow, sugar beet and grass silage) were digested in pilot scale two-stage anaerobic digesters. The specific methane yields obtained were 0.16, 0.38 and 0.39 m3 kg(-1) added volatile solids (VSadded) for willow, sugar beet and grass, respectively, corresponding to yearly gross energy yields of 15, 53 and 26 megawatt-hours (MWh) per hectare. With grass and sugar beets as substrate, 84-85% of the harvestable methane was obtained within 30 days. In pilot scale two-stage digestion of willow and sugar beet, 56 and 85% of the laboratory scale methane yields were obtained, but digestion of grass in two-stage reactors yielded 5% more methane than digestion in laboratory scale complet…
Luminescence of phosphorus containing oxide materials: Crystalline SiO2‐P and 3P2O5⋅7SiO2; CaO⋅P2O5; SrO⋅P2O5 glasses
2014
Luminescence of phosphate glasses such as CaO⋅P2O5 and SrO⋅P2O5 is compared with that of phosphorus doped crystalline α-quartz and phosphosilicate glass with content 3P2O5⋅7SiO2. Water & OH groups are found by IR spectra in these materials. The spectrum of luminescence contains many bands in the range 1.5 - 5.5 eV. The luminescence bands in UV range at 4.5-5 eV are similar in those materials. Decay duration in exponential approximation manifests a time constant about 37 ns. Also a component in μs range was detected. PL band of μs component is shifted to low energy with respect to that of ∼37 ns component. This shift is about 0.6 eV. It is explained as singlet-triplet splitting of excited st…
Pintura califal de Bédar (Almería, 355/966)
2020
Esta investigación se centra en un texto árabe pintado sobre un elemento inusual: una balsa de agua para riego en Bédar (Almería). Junto al epígrafe que la data, hay dibujados dos animales cuadrúpedos que quizá representen una escena de caza y una cenefa decorativa; conserva asimismo otros signos gráficos y diseños muy degradados que no ha sido posible descifrar totalmente. Como hasta ahora no se había determinado su cronología, en este estudio he seguido el método habitual en Epigrafía Árabe: dibujar los trazos visibles y restituir después las partes de pintura desaparecida o muy borrada. Como resultado de este estudio queda de relieve el valor de este destacado documento de la cultura pop…