Search results for "kr"
showing 10 items of 7011 documents
Pain modulates early sensory brain responses to task‐irrelevant emotional faces
2023
Background Pain can have a significant impact on an individual's life, as it has both cognitive and affective consequences. However, our understanding of how pain affects social cognition is limited. Previous studies have shown that pain, as an alarm stimulus, can disrupt cognitive processing when focal attention is required, but whether pain also affects task-irrelevant perceptual processing is unclear. Methods We examined the effect of laboratory-induced pain on event-related potentials (ERPs) to neutral, sad, and happy faces before, during, and after a cold pressor pain. ERPs reflecting different stages of visual processing (P1, N170, and P2) were analyzed. Results Pain decreased the P1 …
Prof. J. Lautenbacha angļu literaturas vēsture XVI. gadsimtenī
1922
Fovisma virziena māksliniecisko izteiksmes līdzekļu iepazīšana vizuālās mākslas stundās 7. klasē
2018
Jevgeņija Maršalova, darba autore, ir izstrādājusi diplomdarbu “Fovisma virziena māksliniecisko izteiksmes līdzekļu iepazīšana vizuālās mākslas stundās 7.klasē”. Diplomdarbu veido 3 daļas un 11 apakšnodaļas. Pirmajā diplomdarba daļā ir strukturēta teorētiska informācija par fovismu kā 20.gadsimta mākslas virzienu un aprakstīti virziena nozīmīgākie pārstavji - mākslinieki Anrī Matiss, Andrē Derēns un Moriss de Vlaminks, ka arī apskatīti motīvi fovistu darbos. Otrajā daļā – fovisma mākslinieciskie izteiksmes līdzekļi, aplūkota krāsas un gaismas, kompozīcijas nozīme glezniecībā un fovistu darbos. Trešajā daļā sniegta informācija par pusaudžu vecuma psiholoģisku raksturojumu, praktisku pedagoģi…
Urban Circular Metabolism as a Generator of Value and Resilient Communities. Creative Recycling of Industrial Architecture: The Case of Nordkraft (Aa…
2022
Aalborg has modified its urban metabolism to overcome the economic-industrial crisis and tackle climate change. The city, however, has not changed its DNA. Without distorting its identity as an industrial city, it has been able to respond to new and unpredictable needs through a process of architectural and urban exaptation. Nordktraft is a significant part of this regeneration process based on sustainability, both from an environmental and socio-cultural point of view, with a vision that is particularly focused on physical health and the growth of the relational life of the population. The vision that inspired the Nordkraft project is that diversity is the most powerful factor fueling resi…
Anti-mikrobiālās plānās kārtiņas: izgatavošanas tehnoloģija un īpašību noteikšana.
2022
Šī pētījuma galvenais mērķis ir izstrādāt plānās kārtiņas pārklājumu ar anti-mikrobiālām īpašībām. Šim mērķim tika pētīts volframa oksīda un vara kombinētas plānās kārtiņas pārklājums uz PET substrāta, kura struktūras parametru pamatā ir caurspīdīgs ap 120 nm biezs volframa oksīda slānis ar tam virsū uzklātu 20 nm vara slāni, kas, savukārt, ir apsegts ar 120 nm volframa oksīda slāni – WOx/Cu/WOx. Anti-mikrobiālo efektu noteikšanai tika adaptētas testēšanas metodoloģijas JIS Z 2801 “Antimicrobial products-Test for antimicrobial activity and efficacy” (Association JS 2001) un ES ISO 22196 “Measurment of antibacterial activity on plastic surfaces” (ES ISO 22196). Testēšana tika veikta ar E.col…
The GAIN-C study (BP25438): Randomized phase II trial of RG7160 (GA201) plus FOLFIRI, compared to cetuximab plus FOLFIRI or FOLFIRI alone in second-l…
2012
TPS3637 Background: GA201 is a novel, dual-acting, humanized, glycoengineered IgG1 anti-EGFR monoclonal antibody, with enhanced antibody-dependent cellular cytotoxicity (ADCC) activity in combination with signal inhibition. GA201 demonstrates significantly enhanced in vitro/vivo activity compared to cetuximab (cet) both as a single agent and in combination with irinotecan, in both KRAS mutant and BRAF mutant models and promising clinical activity in ph I and neo-adjuvant trials (Paz Ares et al, JCO 2011) including KRAS mutant mCRC. A randomized ph II program was launched: one study in NSCLC and GAIN-C in mCRC (NCT01326000), which is presented here. Methods: Main inclusion criteria are prog…
Characterization of the interaction of the antifungal and cytotoxic cyclic glycolipopeptide hassallidin with sterol-containing lipid membranes.
2019
Hassallidins are cyclic glycolipopeptides produced by cyanobacteria and other prokaryotes. The hassallidin structure consists of a peptide ring of eight amino acids where a fatty acid chain, additional amino acids, and sugar moieties are attached. Hassallidins show antifungal activity against several opportunistic human pathogenic fungi, but does not harbor antibacterial effects. However, they have not been studied on mammalian cells, and the mechanism of action is unknown. We purified hassallidin D from cultured cyanobacterium Anabaena sp. UHCC 0258 and characterized its effect on mammalian and fungal cells. Ultrastructural analysis showed that hassallidin D disrupts cell membranes, causin…
Chemical and antifungal investigations of six Lippia species (Verbenaceae) from Brazil
2012
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Toxicological and bioactivity evaluation of blackcurrant press cake, sea buckthorn leaves and bark from Scots pine and Norway spruce extracts under a…
2021
Aqueous extracts from blackcurrant press cake (BC), Norway spruce bark (NS), Scots pine bark (SP), and sea buckthorn leaves (SB) were obtained using maceration and pressurized hot water and tested for their bioactivities. Maceration provided the extraction of higher dry matter contents, including total phenolics (TPC), anthocyanins, and condensed tannins, which also impacted higher antioxidant activity. NS and SB extracts presented the highest mean values of TPC and antioxidant activity. Individually, NS extract presented high contents of proanthocyanidins, resveratrol, and some phenolic acids. In contrast, SB contained a high concentration of ellagitannins, ellagic acid, and quercetin, exp…
Der Philosoph W. Solowioff und das Judentum [Philosoph W. Solowjow und das Judentum]
1927
Inhaltsverzeichnis: Vorwort 5 l. W. Solowioffs und das Judentum ll. W. Solowioffs Protest gegen den Antisemitismus 17 111. Das religiöse Gewissen erweckt in W. S. lnteresse für das Judentum 22 IV. W. Solowioffs Interesse für Juden 29 V. Die Bekanntschaft mit Juden macht W. S. zu ihrem Apologeten 32 VI. Juden zuverteidigen war für W. S. religiöse und patriotische Pflicht 35 Vll. W. Solowioffs jüdische Apologie 39 Vlll. W. S. über das Verhältnis des Christentums zum Judentum 46 IX. W. S. über die Beziehungen der Evangelien zum Talmud 57 X. W. Solowioffs originelle Polemik. 65 Xl. Widerlegung der nationalen Beschuldigungen 74 Xll. Widerlegung der ökonomischen Beschuldigung 77 Xlll. Wideflegung…