Search results for "ligand"

showing 10 items of 2559 documents

Biphenyl macrolactams in anion complexation. Selective naked-eye fluoride recognition

2004

Two colorimetric anion sensors 1 and 2 allow for the selective differentiation of fluoride in the presence of other anions. Two different types of species have been observed in the complexation process, one of them is a co-ordination complex and the other is a salt generated by ligand deprotonation. The deprotonation reaction induces a conformational change, giving rise to a symmetrical species. This species is responsible for colour development. Ligand 3 has a similar structure and does not give rise to any colour modification due to presence of the dimethylamino groups in the biphenyl moiety. The X-ray structure of ligand 2 is also reported and compared with that of ligand 1, that had bee…

Biphenylchemistry.chemical_classificationConformational changeStereochemistryLigandOrganic ChemistrySalt (chemistry)BiochemistryMedicinal chemistrychemistry.chemical_compoundDeprotonationchemistryDrug DiscoveryMoietyNaked eyeFluorideTetrahedron
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Bis(crown ethers) derived from biphenyl: extraction and electrochemical properties

2004

Abstract Ligands derived from 4,4′-dinitrobiphenyl containing azacrown cavities in the 2,2′ position have been used in extraction and transport experiments. Control experiments with a system containing only one complexing cavity have demonstrated that the capability of forming a sandwich-type complex in the aforementioned ligand not only increases extraction but also the transport across a liquid membrane. Extraction studies have also shown that the complex present in the membrane has a 1:1 stoichiometry with regard to both ligands. Electrochemical studies have also been carried out. The ligand containing two complexing cavities is capable of giving rise to a 2:1 complex under electrochemic…

Biphenylchemistry.chemical_compoundMembraneChemistryLigandOrganic ChemistryDrug DiscoveryExtraction (chemistry)Organic chemistryElectrochemistryBiochemistryCombinatorial chemistryStoichiometryTetrahedron
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N-Biphenyl thioureas as carboxylate receptors. Effect of the ligand substituents on the geometry of the complexes

2006

Abstract Six new biphenyl thiourea derivatives have been prepared to be used in carboxylate sensing. Experiments carried out with these ligands have demonstrated that the type of interaction with TBA carboxylates is strongly dependent on the substituents in the thiourea moiety. These interactions go from the formation of 1:1 hydrogen-bonded complexes to acid–base reactions. In addition, different geometries have been observed for the complexes being dependent on the conformations of the free ligands in solution.

Biphenylchemistry.chemical_compoundThioureaChemistryLigandOrganic ChemistryDrug DiscoveryMoietyCarboxylatePhotochemistryReceptorBiochemistryMedicinal chemistryTetrahedron
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Relationship between ligand conformations and complexation properties in ditopic biphenyl thioureas

2007

Four new homoditopic biphenyl thiourea derivatives have been prepared to be used in carboxylate sensing. Experiments carried out with these ligands have demonstrated that the conformation of the free ligand has a strong influence on both complex stoichiometry and geometry. High equilibrium constants were obtained in DMSO.

Biphenylchemistry.chemical_compoundThioureaChemistryStereochemistryLigandOrganic ChemistryDrug DiscoveryPolymer chemistryCarboxylateBiochemistryEquilibrium constantStoichiometryTetrahedron
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Synthesis, solution and electrochemical behaviour of new aza-crown ethers derived from biphenyl

2000

Macrocyclic ligands L1–L4 containing biphenyl units have been synthesized. Potentiometric and voltametric studies in the presence and the absence of transition metal cations have been carried out. The relationship between the conformation of the ligand and oxidation states has been also considered. The crystal structure of [HgL2(CN)2]·2Hg(CN)2 has been elucidated by X-ray diffraction techniques.

Biphenylchemistry.chemical_compoundchemistryTransition metalLigandPolymer chemistryPotentiometric titrationInorganic chemistryGeneral ChemistryCrystal structureElectrochemistryJournal of the Chemical Society, Dalton Transactions
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Hybrid ferrocene ligands (P, N) : synthesis, coordination to metals and applications in arylation coupling catalysis

2017

The research theme developed during this thesis concerns the development of new hybrid ferrocene hybrid (P, N) ligands with controlled conformation, robust and stable to air. These hybrid tetradent ligands comprise two types of coordinating functions with distinct steric and electronic properties. Their coordination chemistry with metals such as gold or palladium has been studied and some isolated Au (I) complexes have been used in the arylation coupling catalysis of aryl iodides.

Bis(aminométhyl)-ferrocèneN) à conformation contrôléeNitrogenCouplage C-CRMN 15NBis (aminomethyl)-ferroceneAzoteFunctionalization of ferrocenePhosphorusOrHybrid ligandsHybrid ligands (PFonctionnalisation de ferrocène[CHIM.OTHE] Chemical Sciences/OtherLigands hybridesPhosphoreLigands hybrides-(PGoldFerrocene15N NMRLigands multidentes[CHIM.OTHE]Chemical Sciences/OtherN) with controlled conformationPalladiumC-C cross Coupling
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CaCl2, Bisoxazoline, and Malonate: A Protocol for an Asymmetric Michael Reaction

2015

A mild protocol for the asymmetric Michael addition of dimethyl malonate to various α,β-unsaturated carbonyl compounds was developed. The salient feature of this methodology is that a cheap and environmentally friendly Lewis acid, CaCl2, was used as a catalyst. An aminoindanol- and pyridine-derived ligand provided in the presence of CaCl2 Michael adducts in moderate to high enantioselectivities. The scope of the reaction was demonstrated.

Bisoxazolineinorganic chemicalsAminoindanol010405 organic chemistryChemistryLigandOrganic ChemistryMalonateCaCl2macromolecular substances010402 general chemistrybehavioral disciplines and activities01 natural sciencesDimethyl malonatehumanities0104 chemical sciencesCatalysisAdductchemistry.chemical_compoundMalonateMichael reactionOrganic chemistryLewis acids and basesta116The Journal of Organic Chemistry
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Metal complexes of an amine bisphenol with a thiophene side-arm

2010

Dioxomolybdenum(VI) and oxotungsten(VI) complexes with a new amine bisphenol ligand (H2L) are reported. The ligand which carries a neutral nitrogen atom, two phenolic oxygen atoms and a thiophene side-arm was synthesized by a simple one-pot Mannich reaction. Further reaction with [MoO2(acac)2] yielded a monomeric molybdenum complex [MoO2(L)(MeOH)] (2a) or a dimeric complex [Mo2O2(μ-O)2(L)2] (2b), depending on the reaction conditions. The reaction with a tungsten trisglycolate [W(eg)3] led to the formation of a monomeric compound [WO(eg)(L)] (3). In these complexes, the potentially tetradentate amine bisphenolate dianion coordinates as a tridentate O,N,O donor while the sulfur side-arm donor…

BisphenolLigandchemistry.chemical_elementGeneral ChemistryMedicinal chemistryMetalchemistry.chemical_compoundMonomerchemistryMolybdenumvisual_artThiophenevisual_art.visual_art_mediumOrganic chemistryAmine gas treatingMannich reactionCollection of Czechoslovak Chemical Communications
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Specific expression of a TRIM-containing factor in ectoderm cells affects the skeletal morphogenetic program of the sea urchin embryo

2011

In the indirect developing sea urchin embryo, the primary mesenchyme cells (PMCs) acquire most of the positional and temporal information from the overlying ectoderm for skeletal initiation and growth. In this study, we characterize the function of the novel gene strim1, which encodes a tripartite motif-containing (TRIM) protein, that adds to the list of genes constituting the epithelial-mesenchymal signaling network. We report that strim1 is expressed in ectoderm regions adjacent to the bilateral clusters of PMCs and that its misexpression leads to severe skeletal abnormalities. Reciprocally, knock down of strim1 function abrogates PMC positioning and blocks skeletogenesis. Blastomere tran…

BlastomeresDNA Complementaryanimal structuresTRIM Sea urchin embryo Ectoderm Skeleton biomineralization Morpholino oligonucleotides Primary mesenchyme Cell migration Guidance otp pax2/5/8 sm30MesenchymeMolecular Sequence DataMorphogenesisSettore BIO/11 - Biologia MolecolareEctodermBiologyLigandsModels BiologicalBone and BonesMesodermCell MovementEctodermGene expressionmedicineAnimalsAmino Acid SequenceMolecular BiologyGeneGeneticsBone DevelopmentSequence Homology Amino AcidGene Expression Regulation DevelopmentalEmbryoBlastomereProtein Structure TertiaryCell biologyTransplantationmedicine.anatomical_structureSea Urchinsembryonic structuresCarrier ProteinsDevelopmental BiologyDevelopment
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Synthesis, structural investigations on organotin(IV) chlorin-e6 complexes, their effect on sea urchin embryonic development and induced apoptosis

2004

Four new organotin(IV) chlorin derivatives, [chlorin=chlorin-e(6)=21H,23H-porphine-2-propanoic acid, 18-carboxy-20-(carboxymethyl)-8-ethenyl-13-ethyl-2,3-di-hydro-3,7,12,17-tetramethyl-(2S-trans)-], with formula (R(2)Sn)(3)(chlorin)(2).2H(2)O (R=Me, n-Bu) and (R(3)Sn)(3)chlorin.2H(2)O (R=Me, Ph) have been synthesized. The solid state and solution phase structures have been investigated by FT-IR, (119)Sn Mössbauer, (1)H and (13)C NMR spectroscopy. In the solid state, (R(2)Sn)(3)(chlorin)(2).2H(2)O complexes contain six coordinated Sn(IV), in a skew trapezoidal environment by forming trans-R(2)SnO(4) polymeric units. As far as (R(3)Sn)(3)chlorin.2H(2)O complexes are concerned, Sn(IV) is five …

BlastomeresSea urchinDenticityMagnetic Resonance SpectroscopyPorphyrinsStereochemistryApoptosisOrganotin(IV)BiochemistryInorganic Chemistrychemistry.chemical_compoundSpectroscopy Mossbauerbiology.animalSpectroscopy Fourier Transform InfraredOrganotin CompoundsAnimalsCarboxylateSea urchinTUNEL assaybiologyChlorophyllidesMolecular StructureCytotoxic activityLigandApoptosiNecrosiChlorin-e6Trigonal bipyramidal molecular geometrychemistryChlorinParacentrotusDNA fragmentation
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