Search results for "monoterpene"

showing 10 items of 145 documents

Lavandula angustifolia Essential Oil and Linalool Counteract Social Aversion Induced by Social Defeat

2018

Many vegetable extracts, essential oils, and their main constituents are active on the Central Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers for their activity in treating CNS disorders. In this research, we studied the possible activities of Lavandula angustifolia (LA) essential oil and of its main constituent, linalool, as anti-stress compounds on anxiety and social interaction and their in vitro effects on proteins (pERK and PKA) involved in the transmission of the signal. An acute intraperitoneal injection of linalool (100 mg/kg) and of LA essential oil (200 mg/kg) reduced motor activity without any anxiolytic effect, but significantly incr…

Central Nervous System30030301 basic medicinelinaloolLavandulaVolatilePharmaceutical SciencePharmacologyAnalytical Chemistrylaw.inventionSocial defeatMicechemistry.chemical_compound0302 clinical medicineAnti-Anxiety AgentsLinaloolCentral Nervous System Diseasessocial defeatlawDrug DiscoveryHypnotics and SedativesEssential oil; Lavandula angustifolia; Linalool; Social defeat; Animals; Anti-Anxiety Agents; Antidepressive Agents; Central Nervous System; Central Nervous System Diseases; Humans; Hypnotics and Sedatives; Interpersonal Relations; Lavandula; Mice; Monoterpenes; Oils Volatile; Analytical Chemistry; Chemistry (miscellaneous); Molecular Medicine; 3003; Drug Discovery3003 Pharmaceutical Science; Physical and Theoretical Chemistry; Organic ChemistryLavandula angustifolia<i>Lavandula angustifolia</i>Antidepressive AgentsLavandulaChemistry (miscellaneous)Molecular MedicineAntidepressantmedicine.drug_classAnxiolyticArticleessential oillcsh:QD241-44103 medical and health scienceslcsh:Organic chemistrymedicineAnimalsHumansInterpersonal RelationsPhysical and Theoretical ChemistryEssential oilbusiness.industryDrug Discovery3003 Pharmaceutical ScienceOrganic Chemistry030104 developmental biologyAnti-Anxiety AgentschemistryLavandula angustifoliaMonoterpenesbusinessOils030217 neurology & neurosurgeryMolecules
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Retention of aroma compounds in starch matrices: competitions between aroma compounds toward amylose and amylopectin

2002

International audience; The retention of three aroma compounds-isoamyl acetate, ethyl hexanoate, and linalool--from starch-containing model food matrices was measured by headspace analysis, under equilibrium conditions. We studied systems containing standard or waxy corn starch with one or two aroma compounds. The three studied aroma compounds interact differently: ethyl hexanoate and linalool form complexes with amylose, and isoamyl acetate cannot. However, in systems containing one aroma compound, we observed with both starches a significant retention of the three molecules. These results indicate that amylopectin could play a role in the retention of aroma. In systems containing two arom…

Chemical PhenomenaStarchAcyclic MonoterpenesIsoamyl acetate01 natural sciencesBinding CompetitiveZea mayschemistry.chemical_compound0404 agricultural biotechnologyPentanolsamyloseAmylose[CHIM.ANAL]Chemical Sciences/Analytical chemistry[SDV.IDA]Life Sciences [q-bio]/Food engineeringAroma compoundOrganic chemistryamylopectinCaproatesAromaWaxy corncomplexesbiologyChemistry Physicalflavor retention010401 analytical chemistryEthyl hexanoatefood and beveragesStarch04 agricultural and veterinary sciencesGeneral Chemistryinteractionsbiology.organism_classification040401 food science0104 chemical scienceschemistryFoodAmylopectinOdorantsMonoterpenesStarch pasteGeneral Agricultural and Biological Sciencescompetition[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Understanding retention and metabolization of aroma compounds using an in vitro model of oral mucosa.

2020

International audience; The mechanism leading to aroma persistence during eating is not fully described. This study aims at better understanding the role of the oral mucosa in this phenomenon. Release of 14 volatile compounds from different chemical classes was studied after exposure to in vitro models of oral mucosa, at equilibrium by Gas-Chromatography-Flame Ionization Detection (GC-FID) and in dynamic conditions by Proton Transfer Reaction- Mass Spectrometry (PTR-MS). Measurements at equilibrium showed that mucosal hydration reduced the release of only two compounds, pentan-2-one and linalool (p < 0.05), and suggested that cells could metabolize aroma compounds from different chemical fa…

Chemical structureTR146/MUC1 cellsAcyclic MonoterpenesKinetics01 natural sciencesGas Chromatography-Mass SpectrometryAnalytical Chemistrychemistry.chemical_compoundEating0404 agricultural biotechnologyLinaloolPentanonesmedicineMoleculeHumans[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringOral mucosaaroma persistenceSalivaAromaaroma metabolismVolatile Organic Compoundsbiologyoral mucosaChemistry010401 analytical chemistryaroma retentionMouth MucosaEthyl hexanoatefood and beverages04 agricultural and veterinary sciencesGeneral Medicinebiology.organism_classification040401 food scienceIn vitro0104 chemical sciencesmedicine.anatomical_structureBiochemistrymucosal pelliclearoma releasein vitro modelOdorants[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood ScienceFood chemistry
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Rearrangement of 4,5-epoxy-9-trimethylsilyldecalines. Application to the synthesis of the natural eremophilane (-)-aristolochene.

2006

Several 4,5-epoxy-9-trimethylsilyl-eudesmanes and 15-nor-eudesmanes, having different relative stereochemistry and substitution at the oxirane ring, have been prepared starting from (-)-carvone and subjected to acid-promoted rearrangement. The presence of the silicon at C9 favors two different main reaction pathways involving C14-methyl or C1-methylene migration through the stabilization of a C10 carbocation intermediate. Selective 1,2-migration of the bridgehead methyl group takes place with trisubstituted beta-epoxide and tetrasubstituted alpha-epoxide, yielding 4-hydroxy-eremophilane and 15-nor-eremophilane compounds, while the trisubstituted alpha-epoxide suffers successive rearrangemen…

ChemistryStereochemistryMonoterpeneOrganic ChemistryMolecular ConformationEpoxideStereoisomerismCarbocationNaphthalenesRing (chemistry)SesquiterpeneChemical synthesischemistry.chemical_compoundOrganic chemistrySelectivityAristolocheneSesquiterpenesThe Journal of organic chemistry
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Deoxyxylulose 5-phosphate reductoisomerase is not a rate-determining enzyme for essential oil production in spike lavender

2014

[EN] Spike lavender (Lavandula latifolia) is an economically important aromatic plant producing essential oils, whose components (mostly monoterpenes) are mainly synthesized through the plastidial methylerythritol 4-phosphate (MEP) pathway. 1-Deoxy-d-xylulose-5-phosphate (DXP) synthase (DXS), that catalyzes the first step of the MEP pathway, plays a crucial role in monoterpene precursors biosynthesis in spike lavender. To date, however, it is not known whether the DXP reductoisomerase (DXR), that catalyzes the conversion of DXP into MEP, is also a rate-limiting enzyme for the biosynthesis of monoterpenes in spike lavender. To investigate it, we generated transgenic spike lavender plants con…

ChlorophyllPhysiologyTransgeneMonoterpeneLavandula latifoliaMonoterpeneGene ExpressionFlowersPlant ScienceEssential oillaw.inventionchemistry.chemical_compoundBiosynthesisTransferaseslawBIOQUIMICA Y BIOLOGIA MOLECULAROils VolatilePlant OilsArabidopsis thalianaAldose-Ketose IsomerasesEssential oilPlant ProteinsATP synthasebiologyArabidopsis ProteinsDXR enzymeDXS enzymeSpike lavenderPlants Genetically Modifiedbiology.organism_classificationCarotenoidsDXP reductoisomerasePlant LeavesErythritolLavandulaPhenotypechemistryBiochemistryMonoterpenesbiology.proteinSugar PhosphatesAgronomy and Crop ScienceJournal of Plant Physiology
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Up-regulation of an N-terminal truncated 3-hydroxy-3-methylglutaryl CoA reductase enhances production of essential oils and sterols in transgenic Lav…

2007

Spike lavender (Lavandula latifolia) essential oil is widely used in the perfume, cosmetic, flavouring and pharmaceutical industries. Thus, modifications of yield and composition of this essential oil by genetic engineering should have important scientific and commercial applications. We generated transgenic spike lavender plants expressing the Arabidopsis thaliana HMG1 cDNA, encoding the catalytic domain of 3-hydroxy-3-methylglutaryl CoA reductase (HMGR1S), a key enzyme of the mevalonic acid (MVA) pathway. Transgenic T0 plants accumulated significantly more essential oil constituents as compared to controls (up to 2.1- and 1.8-fold in leaves and flowers, respectively). Enhanced expression …

ChlorophyllTransgeneArabidopsisStigmasterolLavandula latifoliaMevalonic AcidPlant ScienceMevalonic acidReductaselaw.inventionchemistry.chemical_compoundlawBotanyOils VolatileArabidopsis thalianaCarotenoidEssential oilchemistry.chemical_classificationStigmasterolbiologyPhytosterolsfood and beveragesPigments BiologicalPlants Genetically Modifiedbiology.organism_classificationCarotenoidsSitosterolsUp-RegulationPlant LeavesLavandulachemistryBiochemistryMonoterpenesHydroxymethylglutaryl CoA ReductasesSesquiterpenesAgronomy and Crop ScienceBiotechnologyPlant Biotechnology Journal
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Chemical Composition and Antimicrobial Activity of the Essential Oils from Three Chemotypes of Origanum vulgare L. ssp. hirtum (Link) Ietswaart Growi…

2009

Essential oils obtained from inflorescences of three Origanum vulgare L.ssp. hirtum (Link) Ietswaart samples, growing wild in different locations in Campania (Southern Italy), were analysed. Three chemotypes were found: the first, with a prevalence of carvacrol/thymol; the second, characterized by the prevalence of thymol/alpha-terpineol; the third, featuring a prevalence of linalyl acetate and linalool. This chemical study attempts to provide a contribution in shedding light on the relationship between chemical composition and biotypes and/or chemotypes in Origanum vulgare ssp. hirtum. The essential oils were also evaluated for their antibacterial activity against 10 selected microorganism…

Chromatography GasAcyclic MonoterpenescarvacrolPharmaceutical ScienceCyclohexane MonoterpenesMicrobial Sensitivity TestsLinalyl acetateCymenesArticleGas Chromatography-Mass SpectrometryAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundOriganum vulgare ssp. hirtumantibacterial activitylcsh:Organic chemistryLinaloolOriganumthymolCyclohexenesDrug DiscoveryBotanyOils VolatilePlant OilsCarvacrollinalyl acetatePhysical and Theoretical ChemistryThymolessential oil compositionBacteriabiologyChemotypeOrganic ChemistryOriganum vulgare ssp. hirtum; essential oil composition; thymol; carvacrol; linalyl acetate; antibacterial activityOriganumbiology.organism_classificationAntimicrobialAnti-Bacterial AgentsItalychemistryChemistry (miscellaneous)MonoterpenesCymenesMolecular MedicineMolecules
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Chemotaxonomic value of the essential oil compounds in species of Teucrium pumilum aggregate

2000

Volatile compounds from the aerial parts of Teucrium lepicephalum Pau and Teucrium carolipaui C. Vicioso ex Pau, both belonging to the Teucrium pumilum aggregate, were analysed by capillary GC and GC-MS. From the common and specific compounds (mono- and sesquiterpenes) of the two taxa, chemical characterization was carried out and taxonomic relationships were assessed. Application of the cluster and k-means discriminant analysis shows a differential chemical relationship between T. lepicephalum and Teucrium carolipaui.

Chromatography GasLamiaceaebiologyMonoterpenePlant ScienceGeneral MedicineHorticulturebiology.organism_classificationSesquiterpeneBiochemistrylaw.inventionTeucriumTerpenechemistry.chemical_compoundSpecies SpecificitychemistryChemotaxonomylawBotanyOils VolatileLamiaceaeTaxonomy (biology)VolatilizationMolecular BiologyEssential oilPhytochemistry
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Volatile compounds of flowers and leaves of Sideritis italica (Miller)Greuter et Burdet (Lamiaceae), a plant used as mountain tea

2010

Sideritis italica (Miller) Greuter et Burdet (Lamiaceae), widely used in ethnopharmacological medicine, occurs in Southern Italy and Sicily. The phytochemical composition of the essential oils of S. italica flowers and leaves, harvested in Piano Battaglia (Sicily), was analysed by GC and GC-MS. Of the 51 compounds, 43 in the oil from flowers and 29 in the oil from leaves were identified. Kaur-15-ene (20.0%) was recognised as the main constituent of the oil from flowers, together with beta-cubebene (12.1%), beta-pinene (8.5%), (Z)-nuciferol (6.5%), tricyclene (4.5%) and alpha-bisabolol (4.0%). In the oil from leaves, p-methoxyacetophenone (26.0%) prevailed, as did hexadecanoic acid (21.3%), …

Chromatography GasNonanalPlant compositionPalmitatesPlant ScienceFlowersBiologyBiochemistryGas Chromatography-Mass SpectrometryAnalytical ChemistryPalmitic acidchemistry.chemical_compoundBridged Bicyclo CompoundsBotanyPhytochemical compositionOils VolatileChemical compositionBicyclic Monoterpenesbeta-PineneLamiaceaeTeaOrganic Chemistrybiology.organism_classificationMonocyclic SesquiterpenesPlant LeaveschemistrySideritisMonoterpenesLamiaceaeSesquiterpenes
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Essential oil analysis ofTeucrium libanitisandT. turredanumby GC and GC-MS

2003

The chemical composition of the six essential oils obtained from Teucrium libanitis and Teucrium turredanum collected at different localities was analysed by GC and GC–MS. Fifty-three constituents were identified. The oil of T. libanitis is characterized by the monoterpene α-pinene (9.9–21.2%) and the sesquiterpene δ-cadinene (5.3–9.7%), while that of T. turredanum had a higher content of sesquiterpenoids: β-caryophyllene (15.6–32.6%), α-humulene (4.7–10.1%) and β-bisabolol (6.4–8.3%), and a lower percentage of monoterpenoids (<1%). A multivariate procedure (hierarchical clustering) for detecting natural grouping established that T. libanitis and T. turredanum constitute two independent taxa…

ChromatographybiologyTraditional medicineChemistryMonoterpeneGeneral ChemistryPharmacognosySesquiterpenebiology.organism_classificationlaw.inventionTeucriumchemistry.chemical_compoundlawGas chromatographyGas chromatography–mass spectrometryEssential oilFood ScienceFlavour and Fragrance Journal
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