Search results for "nations"

A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology

2015

Bone morphogenetic proteins (BMPs), members of the TGF-β superfamily, have numerous biological activities including control of growth, differentiation, and vascular development. Using an in vitro co-culture endothelial cord formation assay, we investigated the role of a BMP7 variant (BMP7v) in VEGF, bFGF, and tumor-driven angiogenesis. BMP7v treatment led to disruption of neo-endothelial cord formation and regression of existing VEGF and bFGF cords in vitro. Using a series of tumor cell models capable of driving angiogenesis in vitro, BMP7v treatment completely blocked cord formation. Pre-treatment of endothelial cells with BMP7v significantly reduced their cord forming ability, indicating …

Environmental Features Associated With Older Adults' Physical Activity in Different Types of Urban Neighborhoods.

2020

The authors studied associations of nature- and infrastructure-based features with physical activity (PA) in different urban neighborhood types; 848 community-dwelling people aged 75–90 years reported PA and three perceived nature-based destinations and seven infrastructure-based features as outdoor mobility facilitators. Neighborhood type was defined using a geographic information system based on proximity to central service areas and residential density (city center, subcenter, and dense and dispersed areas outside centers). PA was higher in dense areas and the city center. Binary logistic regression showed that perceiving nature-based destinations increased the odds for higher PA in the …

The economics of tourist destinations

2012

Culinary tourism experiences in agri-tourism destinations and sustainable consumption-Understanding Italian tourists' motivations

2019

Culinary tourism represents an emerging component of the tourism industry and encompasses all the traditional values associated with the new trends in tourism: respect for culture and tradition, authenticity and sustainability. Italy is known worldwide for the richness and variety of its gastronomy, and agri-tourism represents one of the most important places where culinary tourists can experience local food and beverages. By using a modified version of Kim and Eves&rsquo

Street Food as a Special Interest and Sustainable Form of Tourism for Southeast Asia Destinations

2019

Sustainable development is an objective that every destination is aiming at. This chapter provides evidence that street food, as a special interest for of tourism, if appropriately explored, has the potential to contribute significantly to the sustainable tourism development of Southeast Asia, and more generally to emerging destinations. Within this context, there is an opportunity to convert street food into a tourism resource that can align with the SDGs of the UNWTO. From a management point of view, this chapter highlights the fact that destination marketing organisations need to rethink the type of products and services offered to visitors and more importantly how they advertise themsel…

The adenine nucleotide content of rat liver during infusions of carbohydrates and polyols

1972

Injection of large doses of fructose, sorbitol, or a mixture of glucose, fructose and xylitol in rats causes a drop of liver ATP, total adenine nucleotides and Pi and a rise of AMP, which is in agreement with data from the literature. These changes are considered as a transient disturbance of homeostasis by compounds which are rapidly phosporylated in the liver. This is confirmed by the fact that during continuous infusion of these and other compounds at doses of 1,5 g · kg−1 · h−1 there was no such change. It is concluded that infusions of fructose or of the other carbohydrates tested with rates not exceeding those recommended for parenteral nutrition (0,5 g · kg−1 · h−1) are not likely to…

Essays on the Performance, Subsidization and Internationalization of Social Enterprises

2020

Social enterprises are hybrid organizations that tackle societal challenges by using conventional business models. Being hybrid organizations means that social enterprises pursue dual objectives: social (developmental) and financial. By taking performance, subsidization and internationalization perspectives, this thesis contributes to understanding the hybridity of social enterprises and how this hybridity drives their general operations and key decisions such as foreign market selection and targeting strategy.

España inacabada. Organización territorial del Estado, autonomía política y reconocimiento de la diversidad nacional

2021

S’han complert més de tres dècades de vigència de la Constitució de 1978 i, per tant, ja es disposa de prou perspectiva per analitzar el grau d’eficàcia d’un model d’Estat, per alguns, gairebé federal i, per a uns altres, senzillament molt descentralitzat. D’altra banda, a Espanya segueix plenament obert el debat sobre Espanya. Sigui quina sigui l’opinió, la veritat és que el nostre antic problema consumeix una gran part de les energies col·lectives, condiciona àmpliament l’agenda política, genera notables tensions socials i projecta ombres d’incertesa respecte al futur. En aquest treball, s’hi presenta un balanç de les dues qüestions. Després d’oferir un resum breu del procés de construcci…

A Stochastic Model for Population and Well-Being Dynamics

2014

This article presents a stochastic dynamic model to study the demographic evolution per sexes and the corresponding well-being of a general human population. The main model variables are population per sexes and well-being. The considered well-being variable is the Gender-Related Development Index (GDI), a United Nations index. The model's objectives are to improve future well-being and to reach a stable population in a country. The application case consists of adapting, validating, and using the model for Spain in the 2000–2006 period. Some instance strategies have been tested in different scenarios for the 2006–2015 period to meet these objectives by calculating the reliability of the res…

Development discourses of the low human development index : countries in UN post-2015 discussion

2015

This study is about development discourses and agents of the countries with low Human Development Index (HDI) in Africa. It is based on six UN Post-2015 national consultations. These six nations are Burkina Faso, the Democratic Republic of Congo, Ethiopia, Mozambique, Liberia and Zambia. The criteria of data selection involve the level of HDI, language, format of the report and geographical location. The idea about development as discursive constructed social reality is at the focus of theoretical framework. The method is Discourse Analysis (DA) with some Foucauldian characteristics. The research questions are: What kind of specific development discourses and agentive roles are there in pol…