Search results for "nucleus"

showing 10 items of 1803 documents

Molecular bases of anorexia nervosa, bulimia nervosa and binge eating disorder: shedding light on the darkness

2017

International audience; Eating-disorders (EDs) consequences to human health are devastating, involving social, mental, emotional, physical and life-threatening aspects, concluding on impairment and death in cases of extreme anorexia nervosa. It also implies that people suffering an ED need to find psychiatric and psychological help as soon as possible to achieve a fully physical and emotional recovery. Unfortunately, to date, there is a crucial lack of efficient clinical treatment to these disorders. In this review, we present an overview concerning the actual pharmacological and psychological treatments, the knowledge of cells, circuits, neuropeptides, neuromodulators and hormones in the h…

Anorexia NervosaPsychotherapistcognitive-behavioral therapy[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionneuromodulatorsAnorexia nervosa/bulimia03 medical and health sciencesCellular and Molecular NeuroscienceHuman health0302 clinical medicineplacebo-controlled trialBinge-eating disordermesolimbic dopamine systemGeneticsmedicineHumansGenetic Predisposition to DiseaseBulimia NervosaClinical treatmentregulate feeding-behaviornucleus-accumbens shellborderline personality-disordergene-environment interactionsmedicine.disease030227 psychiatryEating disorderssubstance use disordersAnorexia nervosa (differential diagnoses)genetic approachesrandomized controlled-trialEating disordersgenome-wide associationpharmacologyPsychology[SDV.AEN]Life Sciences [q-bio]/Food and NutritionBinge-Eating Disorder030217 neurology & neurosurgeryClinical psychologyJournal of Neurogenetics
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Use of electron spectroscopic imaging to determine element composition of the melanin granules in the stria vascularis of the guinea pig.

1998

Electron spectroscopic imaging (ESI) was used to analyze the element content of melanin granules in the stria vascularis seen in ultrathin sections of Spurr-embedded cochleae of the guinea pig. To determine element composition, ESI images were taken at different ionization edges, and non-specific background signals were subtracted digitally by an image processing system. The presence of calcium and nitrogen in the melanin granules could be demonstrated clearly. The calcium identified in the melanin granules was then compared with the spatial distributions of calcium binding sites after the application of an antimonate precipitation method, which was used to localize loosely bound calcium. D…

AntimonyMaleEndolymphNitrogenGuinea PigsMineralogychemistry.chemical_elementElectronsCalciumCytoplasmic GranulesMelaninGuinea pigchemistry.chemical_compoundImage Processing Computer-AssistedMedicineAnimalsChemical PrecipitationInner earCochleaCell NucleusMelaninsbusiness.industrySpectrum AnalysisCell MembraneStria VascularisGeneral MedicineMicrotomyCochleaMembranemedicine.anatomical_structureOtorhinolaryngologychemistrySubtraction TechniqueBiophysicsCalciumFemalebusinessAntimonateEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
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Infantile intranuclear rod myopathy.

1997

This report concerns three unrelated floppy infants, two girls and one boy, each biopsied at the age of 1 month. They were hypotonic since birth and required artificial ventilation. The two girls died at the ages of 4 and 3½ months, respectively, the boy is still alive at the age of 2 years, but requires assisted ventilation. Each of the three infants showed, by muscle biopsy, abundant intranuclear rods, the boy and one girl also had sarcoplasmic rods, which were not present in the other girl's muscle. Absence of sarcoplasmic rods, but the presence of intranuclear rods could also be documented in her autopsied muscle. Using an antibody against α-actinin, immunoelectron microscopy showed re…

Artificial ventilationMalePediatricsmedicine.medical_specialtygenetic structuresmedicine.medical_treatmentBiopsyMyosinsMyopathies Nemaline03 medical and health sciences0302 clinical medicineFatal Outcome030225 pediatricsmedicineHumansEndotheliumFloppy InfantMicroscopy ImmunoelectronMuscle SkeletalCell Nucleusbusiness.industryInfant NewbornPediatrics Perinatology and Child HealthFemalesense organsNeurology (clinical)Intranuclear Rod Myopathybusiness030217 neurology & neurosurgeryJournal of child neurology
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A molecular phylogeny of bullfinches Pyrrhula Brisson, 1760 (Aves: Fringillidae)

2011

Abstract We present a molecular phylogeny of bullfinches (Pyrrhula Brisson, 1760) based on 2357 bp DNA sequence information of mitochondrial genes (cyt-b, 16S rRNA) and nuclear introns (fib-7, GAPDH-11). The genus is clearly a monophyletic group. Within the limits of Pyrrhula, molecular methods support the subdivision of three main groups: (1) “Southeast-Asian bullfinches” (P. nipalensis and P. leucogenis), (2) “Himalayan bullfinches” (P. aurantiaca, P. erythaca, P. erythrocephala), and (3) “Eurasian bullfinches” (P. pyrrhula s.l.). Within the last group there are four different subgroups: (3a) P. (p.) murina, (3b) P. (p.) cineracea, (3c) P. (p.) griseiventris, and (3d) P. pyrrhula s.str. T…

AsiaPyrrhulaBiogeographyZoologyPinicolaBiologyDNA MitochondrialCoalescent theoryEvolution MolecularMonophylyGenusRNA Ribosomal 16SGeneticsAnimalsMolecular clockMolecular BiologyPhylogenyEcology Evolution Behavior and SystematicsCell NucleusGenetic VariationSequence Analysis DNAbiology.organism_classificationIntronsEuropeMolecular phylogeneticsFinchesMolecular Phylogenetics and Evolution
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Absolute kinematics of radio-source components in the complete S5 polar cap sample: IV. Proper motions of the radio cores over a decade and spectral …

2016

We have carried out a high-precision astrometric analysis of two very-long-baseline-interferometry (VLBI) epochs of observation of the 13 extragalactic radio sources in the complete S5 polar cap sample. The VLBI epochs span a time baseline of ten years and enable us to achieve precisions in the proper motions of the source cores up to a few micro-arcseconds per year. The observations were performed at 14.4 GHz and 43.1 GHz, and enable us to estimate the frequency core-shifts in a subset of sources, for which the spectral-index distributions can be computed. We study the source-position stability by analysing the changes in the relative positions of fiducial source points (the jet cores) ove…

AstrofísicaActive galactic nucleusAstrometriaAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysicsKinematics01 natural sciencesStability (probability)Radio continuum: generalBinary black hole0103 physical sciencesVery-long-baseline interferometry010306 general physicsInstrumentation and Methods for Astrophysics (astro-ph.IM)010303 astronomy & astrophysicsAstrophysics::Galaxy AstrophysicsPhysicsJet (fluid)general [Radio continuum]general [BL Lacertae objects]Astrophysics::Instrumentation and Methods for AstrophysicsAstronomy and Astrophysicsgeneral [Quasars]BL Lacertae objects: generalAstrometryAstrometryAstrophysics - Astrophysics of GalaxiesQuasars: generalGravitational lensSpace and Planetary ScienceAstrophysics of Galaxies (astro-ph.GA)Techniques: interferometricinterferometric [Techniques]Astrophysics - Instrumentation and Methods for Astrophysics
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The gamma-ray emitting radio-loud narrow-line Seyfert 1 galaxy PKS 2004-447 I. The X-ray View

2015

As part of the TANAMI multiwavelength progam, we discuss new X-ray observations of the $\gamma$-ray and radio-loud Narrow Line Seyfert galaxy ($\gamma$-NLS1) PKS 2004-447. The active galaxy is a member of a small sample of radio-loud NLS1s detected in $\gamma$-rays by the Fermi Large Area Telescope. It is the radio-loudest and only southern-hemisphere source in this sample. We present results from our X-ray monitoring program comprised of Swift snapshot observations from 2012 through 2014 and two new X-ray observations with XMM-Newton in 2012. We analyze the X-ray spectrum and variability of this peculiar source using supplementary archival data from 2004 and 2011. The (0.5-10) keV spectrum…

AstrofísicaActive galactic nucleusAstronomyAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesRadio spectrumlaw.inventionTelescopeRelativistic beaminglaw0103 physical sciencesVery-long-baseline interferometryBlazar010303 astronomy & astrophysicsAstrophysics::Galaxy AstrophysicsPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)010308 nuclear & particles physicsAstronomy and AstrophysicsMonitoring programAstrophysics - Astrophysics of GalaxiesGalaxySpace and Planetary ScienceAstrophysics of Galaxies (astro-ph.GA)AstronomiaComputingMethodologies_DOCUMENTANDTEXTPROCESSINGAstrophysics - High Energy Astrophysical Phenomena
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LeMMINGs III. The e-MERLIN legacy survey of the Palomar sample: exploring the origin of nuclear radio emission in active and inactive galaxies throug…

2021

Full list of authors: Baldi, R. D.; Williams, D. R. A.; Beswick, R. J.; McHardy, I.; Dullo, B. T.; Knapen, J. H.; Zanisi, L.; Argo, M. K.; Aalto, S.; Alberdi, A.; Baan, W. A.; Bendo, G. J.; Fenech, D. M.; Green, D. A.; Klöckner, H. -R.; Körding, E.; Maccarone, T. J.; Marcaide, J. M.; Mutie, I.; Panessa, F.; Pérez-Torres, M. A.; Romero-Cañizales, C.; Saikia, D. J.; Saikia, P.; Shankar, F.; Spencer, R. E.; Stevens, I. R.; Uttley, P.; Brinks, E.; Corbel, S.; Martí-Vidal, I.; Mundell, C. G.; Pahari, M.; Ward, M. J.

AstrofísicaActive galactic nucleusAstronomyAstrophysics::High Energy Astrophysical Phenomenanuclei [galaxies]jets [galaxies]Doubly ionized oxygenFOS: Physical sciencesAstrophysicsF500Astrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesRadio continuum: galaxiesLuminosityAstrophysical jetSubatomic Physics0103 physical sciencesAstronomy Astrophysics and CosmologyAstrophysics::Solar and Stellar AstrophysicsConnection (algebraic framework)010303 astronomy & astrophysicsAstrophysics::Galaxy AstrophysicsGalaxies: nucleiAstronomia ObservacionsHigh Energy Astrophysical Phenomena (astro-ph.HE)Physics[SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph]Galaxies: star formation010308 nuclear & particles physicsAstronomy and AstrophysicsGalaxies: activeAstrophysics - Astrophysics of Galaxiesgalaxies [radio continuum]Accretion (astrophysics)Galaxy[SDU]Sciences of the Universe [physics]Meteorology and Atmospheric SciencesSpace and Planetary ScienceGalaxies: jetsAstrophysics of Galaxies (astro-ph.GA)active [galaxies]Production (computer science)star formation [galaxies]Astrophysics - High Energy Astrophysical Phenomena
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Event Horizon Telescope observations of the jet launching and collimation in Centaurus A

2021

Full list of authors: Janssen, Michael; Falcke, Heino; Kadler, Matthias; Ros, Eduardo; Wielgus, Maciek; Akiyama, Kazunori; Baloković, Mislav; Blackburn, Lindy; Bouman, Katherine L.; Chael, Andrew; Chan, Chi-kwan; Chatterjee, Koushik; Davelaar, Jordy; Edwards, Philip G.; Fromm, Christian M.; Gómez, José L.; Goddi, Ciriaco; Issaoun, Sara; Johnson, Michael D.; Kim, Junhan; Koay, Jun Yi; Krichbaum, Thomas P.; Liu, Jun; Liuzzo, Elisabetta; Markoff, Sera; Markowitz, Alex; Marrone, Daniel P.; Mizuno, Yosuke; Müller, Cornelia; Ni, Chunchong; Pesce, Dominic W.; Ramakrishnan, Venkatessh; Roelofs, Freek; Rygl, Kazi L. J.; van Bemmel, Ilse; Event Horizon Telescope Collaboration.--This Open Access artic…

AstrofísicaActive galactic nucleusCosmology and Nongalactic Astrophysics (astro-ph.CO)010504 meteorology & atmospheric sciencesEvent horizonastro-ph.GAAstronomyAstrophysics::High Energy Astrophysical PhenomenaAstrophysics - astrophysics of galaxiesAstrophysics - cosmology and nongalactic astrophysicsCentaurus AFOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesAstrophysics - high energy astrophysical phenomena0103 physical sciencesVery-long-baseline interferometry010303 astronomy & astrophysicsAstrophysics::Galaxy Astrophysics0105 earth and related environmental sciencesAstronomia ObservacionsEvent Horizon TelescopePhysicsastro-ph.HEHigh Energy Astrophysical Phenomena (astro-ph.HE)Supermassive black holeJet (fluid)Galactic CenterAstronomy and AstrophysicsAstrophysics of Galaxies (astro-ph.GA)astro-ph.CO
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Hints of an axion-like particle mixing in the GeV gamma-ray blazar data?

2013

Axion-Like Particles (ALPs), if exist in nature, are expected to mix with photons in the presence of an external magnetic field. The energy range of photons which undergo strong mixing with ALPs depends on the ALP mass, on its coupling with photons as well as on the external magnetic field and particle density configurations. Recent observations of blazars by the Fermi Gamma-Ray Space Telescope in the 0.1-300 GeV energy range show a break in their spectra in the 1-10 GeV range. We have modeled this spectral feature for the flat-spectrum radio quasar 3C454.3 during its November 2010 outburst, assuming that a significant fraction of the gamma rays convert to ALPs in the large scale jet of thi…

AstrofísicaActive galactic nucleusPhotonAxionsAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesAstrophysics01 natural sciencesPartícules (Física nuclear)Spectral lineHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)0103 physical sciencesBlazar010303 astronomy & astrophysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)PhysicsActive galactic nucleiRange (particle radiation)Cosmologia010308 nuclear & particles physicsGamma rayAstronomy and AstrophysicsQuasarHigh Energy Physics - Phenomenology13. Climate actionAstrophysics - High Energy Astrophysical PhenomenaFermi Gamma-ray Space TelescopeJournal of Cosmology and Astroparticle Physics
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Why Have Many of the Brightest Radio-loud Blazars Not Been Detected in Gamma-Rays by Fermi?

2015

We use the complete MOJAVE 1.5 Jy sample of active galactic nuclei (AGNs) to examine the gamma-ray detection statistics of the brightest radio-loud blazars in the northern sky. We find that 23% of these AGNs were not detected above 0.1 GeV by the Fermi-LAT during the four-year 3FGL catalog period partly because of an instrumental selection effect and partly due to their lower Doppler boosting factors. Blazars with synchrotron peaks in their spectral energy distributions located below 10^(13.4) Hz also tend to have high-energy peaks that lie below the 0.1 GeV threshold of the LAT, and are thus less likely to be detected by Fermi. The non-detected AGNs in the 1.5 Jy sample also have significa…

AstrofísicaActive galactic nucleusmedia_common.quotation_subjectAstrophysics::High Energy Astrophysical Phenomenajets [galaxies]AstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysicsgeneral [gamma-ray burst]7. Clean energy01 natural scienceslaw.inventionsymbols.namesakelaw0103 physical sciencesBlazar010303 astronomy & astrophysicsAstrophysics::Galaxy Astrophysicsmedia_commonPhysicsgeneral [quasars]010308 nuclear & particles physicsScatteringSpectral densityAstronomy and Astrophysicsgalaxies [radio continuum]Synchrotron13. Climate actionSpace and Planetary ScienceSkyactive [galaxies]AstronomiasymbolsDoppler effectFermi Gamma-ray Space Telescope
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