Search results for "pooling"
showing 10 items of 36 documents
Leading indicator properties of US high-yield credit spreads.
2010
Abstract In this paper we examine the out-of-sample forecast performance of high-yield credit spreads for real-time and revised data regarding employment and industrial production in the US. We evaluate models using both a point forecast and a probability forecast exercise. Our main findings suggest that the best results come from using only a few factors obtained by pooling information from a number of sector-specific high-yield credit spreads. In particular, for employment and at short-run horizons, there is a gain from using a principal components model fitted to high-yield credit spreads compared to the prediction produced by benchmarks. Moreover, forecast results based on revised data …
Open innovation: A real option to restore value to the biopharmaceutical R&D
2014
Abstract The pharmaceutical landscape has changed, and new business models, based on alliances, are increasingly being adopted in this industry. Biotechnology advances have pushed this development, and pooling complementary resources coming from incumbents and newcomers is a key skill to succeed: these are the premises for a quick spread of the open innovation (OI) paradigm in this industry. RD to achieve this goal the authors propose a closed-form model that is easy to implement, to evaluate the OI initiative for selecting an optimal RD i.e. licensing-in or not) and the self-financing policy. The proposed model can be easily implemented into a spreadsheet, and the inputs needed to run it a…
The Media as a Policy Instrument in Influencing the Business Model of Professional Soccer. Evidence from Italy
2012
Italian soccer clubs in the first division have individually sold broadcasting rights for their home matches, until new laws imposed pooling and joint-selling those rights through the league and established a mandatory sharing rule to redistribute revenues in order to improve on-the-pitch competitive balance (CB). This article compares the two institutional designs. While reducing revenue inequality, the new regime distorts allocative efficiency and informational rent appropriation, opens up costly ex post renegotiations and antitrust litigations, and does not improve CB.
Adaptive Distance-Based Pooling in Convolutional Neural Networks for Audio Event Classification
2020
In the last years, deep convolutional neural networks have become a standard for the development of state-of-the-art audio classification systems, taking the lead over traditional approaches based on feature engineering. While they are capable of achieving human performance under certain scenarios, it has been shown that their accuracy is severely degraded when the systems are tested over noisy or weakly segmented events. Although better generalization could be obtained by increasing the size of the training dataset, e.g. by applying data augmentation techniques, this also leads to longer and more complex training procedures. In this article, we propose a new type of pooling layer aimed at …
Interest of exome sequencing trio-like strategy based on pooled parental DNA for diagnosis and translational research in rare diseases.
2021
Abstract Background Exome sequencing (ES) has become the most powerful and cost‐effective molecular tool for deciphering rare diseases with a diagnostic yield approaching 30%–40% in solo‐ES and 50% in trio‐ES. We applied an innovative parental DNA pooling method to reduce the parental sequencing cost while maintaining the diagnostic yield of trio‐ES. Methods We pooled six (Agilent‐CRE‐v2–100X) or five parental DNA (TWIST‐HCE–70X) aiming to detect allelic balance around 8–10% for heterozygous status. The strategies were applied as second‐tier (74 individuals after negative solo‐ES) and first‐tier approaches (324 individuals without previous ES). Results The allelic balance of parental‐pool v…
Agencification of the European Union Administration: Connecting the Dots
2016
This review paper, with a clear political science and public administration bias, takes stock of the existing literature on EU agencies and suggests a future research agenda in this area. We review studies on EU agencies’ organization, tasks, proliferation and location in the political-administrative space. Whether the advent of EU agencies tends to underpin a basically intergovernmental, transnational or supranational order is a major topic with potentially huge consequences for the distribution of power across levels of government, for the degree of policy uniformity and pooling of administrative resources across countries, for the role of genuinely European perspectives in the policy pro…
Changing commuters’ mobility behaviors of university campuses: environmental and energy comparisons
2021
Governments are required to take proper measures to promote the use of electric and hybrid vehicles and, more generally, to push people towards sweeter modalities including walking and biking. To reach such tight and challenging goals, local institutions should be deeply involved, and universities among them. The promotion of sustainable mobility practices among commuter students must be considered indeed an effective contribution to facilitating the transition towards greener cities. On purpose, students of the University of Palermo that daily commute from their residences to the campus are considered here. These commuters, in fact, mainly adopt traditional polluting transportation means. …
PNeuro: A scalable energy-efficient programmable hardware accelerator for neural networks
2018
Proceedings of a meeting held 19-23 March 2018, Dresden, Germany; International audience; Artificial intelligence and especially Machine Learning recently gained a lot of interest from the industry. Indeed, new generation of neural networks built with a large number of successive computing layers enables a large amount of new applications and services implemented from smart sensors to data centers. These Deep Neural Networks (DNN) can interpret signals to recognize objects or situations to drive decision processes. However, their integration into embedded systems remains challenging due to their high computing needs. This paper presents PNeuro, a scalable energy-efficient hardware accelerat…
Cash pooling: An organizational response to institutional complexity
2020
The paper aims to explain how new cash management practices can be used to address institutional complexity in Multinational Enterprises (MNEs) and which are the effects on the organizational form....
Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and …
2016
WOS: 000393031600001