Search results for "randomized controlled trial"

Opinion of the Patients About an Internet-Based Psychological Treatment Protocol

2015

Emotional disorders (depression and anxiety disorders) are highly prevalent. Currently, there is evidence showing the efficacy of disorder-specific cognitive-behavior therapy for emotional disorders. However, high comorbidity rates among emotional disorders have led some researchers to shift the focus to treatment strategies that might be more widely effective across these diverse conditions (transdiagnostic approach). Another important line of research in the literature is Internet-based psychotherapy. An increasing number of meta-analyses have shown the efficacy and effectiveness of Internet-based cognitive-behavior treatment protocols for emotional disorders. Nevetherless, little is know…

Research protocol: Technology-supported guidance to increase flexibility, quality and efficiency in the clinical practicum of nursing education

2020

Abstract This paper presents the protocol for a randomized controlled trial aimed at studying the effects of a technology-supported guidance model delivered by smartphone and intended to strengthen the follow-up of nursing students during their clinical practicum. The research outcomes will reflect students’ critical thinking, learning outcomes, and satisfaction. The results will be compared before and after the intervention and between control and intervention groups. In the control group, the clinical practicum period will be performed as usual. In the intervention group, students will monitor their day by filling in daily electronic reports. Based on students’ reports and the day’s exper…

Therapeutic exercise training to reduce chronic headache in working women: a protocol of randomised controlled trial

2015

Erratum to: ‘Home-based palliative approach for people with severe multiple sclerosis and their carers: study protocol for a randomized controlled tr…

2016

EPA-0492 - Functional remediation in bipolar II patients: improvement of functioning and subsyndromal symptoms

2014

Introduction Recently, Functional Remediation (FR) has proven to be effective in improving the functional outcome of euthymic bipolar patients. Objective Our objective was to test the efficacy of FR programme in a subsample of euthymic bipolar II patients (BPII). Aims The main aim was improve the functional outcome in these patients. Method Post-hoc analyses were undertaken using data of 53 DSM-IV diagnosed BPII outpatients who had participated in a multicentre, rater blind, randomized, controlled trial (RCT) exploring the efficacy of FR (n=17) as compared with a Psychoeducation (PSY) (n=19) and a control (n=17) groups which only treatment as usual (TAU). The primary outcome variable was a …

SOPHO-NET – Forschungsverbund zur Psychotherapie der Sozialen Phobie

2009

This paper presents the Social Phobia Psychotherapy Research Network (SOPHO-NET). SOPHO-NET is among the five research networks on psychotherapy funded by "Bundesministerium fur Bildung und Forschung". The research program encompasses a coordinated group of studies of social phobia. In the central project (Study A), a multi-center randomized controlled trial, refined models of manualized cognitive-behavioral therapy (CBT) and manualized short-term psychodynamic psychotherapy (STPP) are compared in the treatment of social phobia. A sample of n=512 outpatients will be randomized to either CBT, STPP or wait list. For quality assurance and treatment integrity, a specific project has been establ…

2020

IntroductionSuccess rates of psychotherapy in post-traumatic stress disorder related to childhood maltreatment (PTSD-CM) are limited.Methods and analysisObserver-blind multicentre randomised clinical trial (A-1) of 4-year duration comparing enhanced methods of STAIR Narrative Therapy (SNT) and of trauma-focused psychodynamic therapy (TF-PDT) each of up to 24 sessions with each other and a minimal attention waiting list in PTSD-CM. Primary outcome is severity of PTSD (Clinician-Administered PTSD Scale for DSM-5 total) assessed by masked raters. For SNT and TF-PDT, both superiority and non-inferiority will be tested. Intention-to-treat analysis (primary) and per-protocol analysis (secondary).…

A Multicentre, Randomised, Controlled Trial of a Combined Clinical Treatment for First-Episode Psychosis

2021

Introduction: There is evidence that early intervention contributes to improving the prognosis and course of first-episode psychosis (FEP). However, further randomised treatment clinical trials are needed. Objectives: The aim of this study was to compare the efficacy of a combined clinical treatment involving Cognitive Behavioural Therapy (CBT) as an adjunctive to treatment-as-usual (TAU) (CBT+TAU) versus TAU alone for FEP. Patients and methods: In this multicentre, single-blind, randomised controlled trial, 177 participants were randomly allocated to either CBT+TAU or TAU. The primary outcome was post-treatment patient functioning. Results: The CBT+TAU group showed a greater improvement in…

Revisión de evidencias de las técnicas de DIR/Floortime™ para la intervención en niños y niñas con Trastornos del Espectro del Autismo

2020

The techniques of DIR/Floortime™ have taken a certain momentum in our country. The aim of this article is to analyze the evidence on the efficacy of these techniques for which four databases have been searched (PsychArticles, ERIC, PubMed and Medline). After refining the documents found by applying the inclusion/exclusion criteria, only 18 empirical studies were detected (7 single case studies, 3 quasi-experimental studies and 6 randomized clinical trials). Two of the studies are re-analyses of previous studies or follow-up studies. Once the different studies have been evaluated, it is concluded that more research is needed on the techniques of DIR/Floortime™. Although the evidence points t…

[Clinical equipoise and systematic reviews of randomized controlled trials].

2015

.Para poder valorar la validez de un ensayo cli´nico es necesarioque su disen˜o, ejecucio´n y ana´lisis se describan con suficientedetalle, exactitudytransparencia.Sinembargo,existennumerososejemplos en la literatura cienti´fica que ponen de manifiesto co´mola informacio´n facilitada en las publicaciones es muchas vecesdeficiente, y que con frecuencia se presentan problemas metodo-lo´gicos graves