Search results for "scad"
showing 10 items of 348 documents
ChemInform Abstract: Asymmetric Synthesis of Cyclopentanes Bearing Four Contiguous Stereocenters via an NHC-Catalyzed Michael/Michael/Esterification …
2016
An NHC-catalyzed Michael/Michael/esterification domino reaction via homoenolate/enolate intermediates for the asymmetric synthesis of tetrasubstituted cyclopentanes bearing four contiguous stereocenters is described. A variety of α,β-unsaturated aldehydes and 2-nitroallylic acetates react well with good domino yields and high stereoselectivities.
Asymmetric synthesis of cyclopentanes bearing four contiguous stereocenters via an NHC-catalyzed Michael/Michael/esterification domino reaction.
2016
An NHC-catalyzed Michael/Michael/esterification domino reaction via homoenolate/enolate intermediates for the asymmetric synthesis of tetrasubstituted cyclopentanes is described.
Measurement of the Atmospheric ve flux in IceCube
2012
We report the first measurement of the atmospheric electron neutrino flux in the energy range between approximately 80 GeV and 6 TeV, using data recorded during the first year of operation of IceCube's DeepCore low energy extension. Techniques to identify neutrinos interacting within the DeepCore volume and veto muons originating outside the detector are demonstrated. A sample of 1029 events is observed in 281 days of data, of which 496 $\pm$ 66(stat.) $\pm$ 88(syst.) are estimated to be cascade events, including both electron neutrino and neutral current events. The rest of the sample includes residual backgrounds due to atmospheric muons and charged current interactions of atmospheric muo…
Motores de búsqueda y derechos de autor: infracción y responsabilidad
2015
Los motores de búsqueda se configuran como herramientas indispensables para localizar fácilmente cualquier tipo de información entre las más de tres billones de páginas web existentes en la red. Estos buscadores se presentan, de facto, como instrumentos básicos para que todo usuario pueda tener acceso a la información, cultura y educación, de manera que están convirtiéndose en unas herramientas indispensables para el libre desarrollo de las personas. Sin embargo, a pesar de estas ventajas, en ocasiones, los buscadores vuelcan contenidos protegidos en la página de resultados sin autorización de su titular, de forma que de no mediar algún límite o excepción tasado en la ley, pueden estar vuln…
DNA-Based Enzyme Reactors and Systems
2016
During recent years, the possibility to create custom biocompatible nanoshapes using DNA as a building material has rapidly emerged. Further, these rationally designed DNA structures could be exploited in positioning pivotal molecules, such as enzymes, with nanometer-level precision. This feature could be used in the fabrication of artificial biochemical machinery that is able to mimic the complex reactions found in living cells. Currently, DNA-enzyme hybrids can be used to control (multi-enzyme) cascade reactions and to regulate the enzyme functions and the reaction pathways. Moreover, sophisticated DNA structures can be utilized in encapsulating active enzymes and delivering the molecular…
Top consumer abundance influences lake methane efflux
2015
Lakes are important habitats for biogeochemical cycling of carbon. The organization and structure of aquatic communities influences the biogeochemical interactions between lakes and the atmosphere. Understanding how trophic structure regulates ecosystem functions and influences greenhouse gas efflux from lakes is critical to understanding global carbon cycling and climate change. With a whole-lake experiment in which a previously fishless lake was divided into two treatment basins where fish abundance was manipulated, we show how a trophic cascade from fish to microbes affects methane efflux to the atmosphere. Here, fish exert high grazing pressure and remove nearly all zooplankton. This re…
Thromboinflammation and Vascular Dysfunction.
2018
Thromboinflammation and vascular dysfunction are inseparably combined with the innate and the adaptive immune response. While the role of this interplay has gained considerable attention in the arena of atherosclerosis/atherothrombosis and in deep vein thrombosis, its role in other forms of vascular disease and risk factors is currently emerging. In this brief review, we will focus on thromboinflammation with regard to cytokine signalling as well as on the novel role of a vascular coagulation-inflammatory circuit in arterial hypertension.Thrombo-Inflammation und vaskuläre Dysfunktion sind untrennbar mit dem angeborenen und dem erworbenen Immunsystem verbunden. Dieses Zusammenspiel wurde im …
Mechanistic details of the domino reaction of nitronaphthalenes with the electron-rich dienes. A DFT study
2008
Abstract The reaction of 1-nitronaphthalene ( 1 ) with the Danishefsky diene ( 2 ) to give the dihydrophenanthrene derivative 11 has been theoretically studied using DFT methods. This reaction is a domino process that is initialized by a polar Diels–Alder reaction between 1 and 2 to give the formally [2 + 4] cycloadduct 3 . The subsequent concerted elimination of nitrous acid ( 4 ) from 3 yields 11 . Analysis of the global reactivity indices as well as the thermodynamic data for this domino process indicate that while the large electrophilic character of 1 together with the large nucleophilic character of 2 are responsible for the participation of these reagents in a polar Diels–Alder react…
Theoretical study on the mechanism of the domino reactions of tertiary α-cyano-enamines and dimethyl acetylenedicarboxylate
2001
Abstract The mechanisms of the domino reaction between dimethyl acetylenedicarboxylate, 1 , and 2-( N , N -dimethylamino)acrylonitrile, 2 , and these in presence of acrylonitrile have been theoretically studied using ab initio methods. These domino reactions comprise several pericyclic-type reactions. The geometrical and electronic analysis of the HF/6-31G ∗ transition structures and intermediates allows characterizing the processes that take place along these domino reactions. B3LYP/6-31G ∗ energetic results are in agreement with the experimental outcomes.
Un altro precursore di Francesco Scaduto: Giuseppe Ingoglia
2011
Contributo destinato alla pubblicazione negli Atti del convegno su “Il contributo di Francesco Scaduto alla scienza giuridica” (Palermo, 18 -19 febbraio 2005) per i tipi della Cedam. SOMMARIO: 1. Premessa - 2. L’attività accademica – 3. Il metodo d’insegnamento - 4. Influenze sugli orientamenti enunciati dallo Scaduto. Conclusioni.