Search results for "script"
showing 10 items of 5143 documents
Textos mèdics, morals i culinaris en un còdex valencià excepcional. Anàlisi del ms. 216 de la Biblioteca Històrica de la Universitat de València
2015
[cat] Estudi i proposta de reconstrucció del ms. 216 de la Biblioteca Històrica de la Universitat de València. Es tracta d'un còdex de la primera meitat del s. XV, actualment restaurat, que ha patit importants pèrdues de folis, mentre que altres han estat relligats en ordre incorrecte. El volum conté obres mèdiques i doctrinals, com ara traduccions catalanes del Thesarus pauperum de Pere Hispà, del Macer floridus d'Odó de Meung o del llibre II dels Disticha Catonis, i també obres escrites originalment en català, com el Llibre de Sent Soví i els Mil proverbis de Ramon Llull. El mal estat del volum ha dificultat la constatació d'alguns aspectes relatius a la seva constitució, que apunten vers…
Semblanza iconográfica de la realeza sapiencial de Alfonso X: las miniaturas liminares de los códices regios
2016
La producción libraria de Alfonso X testimonia la simbiosis perfecta entre las funciones de gobierno y la labor intelectual y sistematiza su ideario político y cultural, no solo en texto, sino también en imagen. A partir de las miniaturas liminares de los códices regios, se evidencia que el motivo icónico privilegiado en la representación personal de Alfonso X es el rey con el libro: se analizan las distintas variantes de este modelo iconográfico que estampa la amplia gama de atribuciones que conforman el concepto de autoría alfonsí y consolida el modelo de la realeza sapiencial castellana.
El «llibre cortés de lectura» en català: a propòsit del manuscrit F-129 del Col·legi de la Sapiència de Palma
2006
The manuscript F-129 of the Col·legi de la Sapiència de Palma contains three works of Ramon Llull. It is made up of two separate manuscripts belonging to the first generation of Lullian codices (that is, not later than the first quarter of the fourteenth century). This collection is preceded by a remarkable full-page illustration, an analysis of which shows that it was probably based on a similar miniature from a French codex emanating from Llull’s immediate circle. The codicological model applicable to this manuscrit is that of «libro cortese di lettura».
El nou paradigma dels estudis de traducció: (notes arran d'un article de Mona Baker)
2006
This introduction tries to contextualize Mona Baker’s article in this same issue by revising her personal evolution in the field of Translation Studies, as well as by introducing some of the key notions tackled in her paper. The introduction mainly deals with the turn of Translation Studies into a new ideological paradigm which tries to overcome the alleged scientific and aseptic methodology of Descriptive Translation Studies. The concepts of descriptive methodology, ideology, frame and narrative theory are also discussed, with some examples of recent events. Attention is also paid to the Catalan context, where translations and language use also obey to certain ideological and political age…
Parasite presence induces gene expression changes in an ant host related to immunity and longevity
2021
Most species are either parasites or exploited by parasites, making parasite&ndash
The distributions of protein coding genes within chromatin domains in relation to human disease.
2019
Abstract Background Our understanding of the nuclear chromatin structure has increased hugely during the last years mainly as a consequence of the advances in chromatin conformation capture methods like Hi-C. The unprecedented resolution of genome-wide interaction maps shows functional consequences that extend the initial thought of an efficient DNA packaging mechanism: gene regulation, DNA repair, chromosomal translocations and evolutionary rearrangements seem to be only the peak of the iceberg. One key concept emerging from this research is the topologically associating domains (TADs) whose functional role in gene regulation and their association with disease is not fully untangled. Resul…
cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel
2020
Abstract Background Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but our understanding of how the effects of genetic variants affect different molecular mechanisms to determine gut immunocompetence is still limited. Results To address this, we perform a systems genetics analysis of the gut transcriptomes from 38 DGRP lines that were orally infected with Pseudomonas entomophila. We identify a large number of condition-specific, expression quantitative trait loci (local-eQTLs) with infection-specific ones located …
3 ′-5 ′ crosstalk contributes to transcriptional bursting
2019
Abstract Background Transcription in mammalian cells is a complex stochastic process involving shuttling of polymerase between genes and phase-separated liquid condensates. It occurs in bursts, which results in vastly different numbers of an mRNA species in isogenic cell populations. Several factors contributing to transcriptional bursting have been identified, usually classified as intrinsic, in other words local to single genes, or extrinsic, relating to the macroscopic state of the cell. However, some possible contributors have not been explored yet. Here, we focus on processes at the 3 ′ and 5 ′ ends of a gene that enable reinitiation of transcription upon termination. Results Using Bay…
Cytoplasmic 5′-3′ exonuclease Xrn1p is also a genome-wide transcription factor in yeast
2014
The 5′ to 3′ exoribonuclease Xrn1 is a large protein involved in cytoplasmatic mRNA degradation as a critical component of the major decaysome. Its deletion in the yeast Saccharomyces cerevisiae is not lethal, but it has multiple physiological effects. In a previous study, our group showed that deletion of all tested components of the yeast major decaysome, including XRN1, results in a decrease in the synthetic rate and an increase in half-life of most mRNAs in a compensatory manner. Furthermore, the same study showed that the all tested decaysome components are also nuclear proteins that bind to the 5′ region of a number of genes. In the present work, we show that disruption of Xrn1 activi…
Monitoring the quality of the hospital pharmacoterapeutic process by sentinel patient program
2018
To analyze the results of sentinel patient program to monitoring the quality pharmacoterapeutic process in the hospitalized patient through medication errors.Design: Observational, prospective and transversal study. Ambit: General hospital of 1,000 beds.From May 2011 to June 2016. Sample: Patients with treatment prescribe within 24 hours of being admitted with 4 or more medications.Medication error, drugs prescribed, medications and doses dispensing, drugs administered. Safety indicators were defined based on medication errors at each stage of the pharmacotherapeutic process.Of the 746 patients studied, 334 had at least 1 medication error (44.8%; IC95%: 41.7-47.8). In the 746 treatm…