Search results for "sma"

showing 10 items of 9566 documents

Natural Selection Fails to Optimize Mutation Rates for Long-Term Adaptation on Rugged Fitness Landscapes

2008

The rate of mutation is central to evolution. Mutations are required for adaptation, yet most mutations with phenotypic effects are deleterious. As a consequence, the mutation rate that maximizes adaptation will be some intermediate value. Here, we used digital organisms to investigate the ability of natural selection to adjust and optimize mutation rates. We assessed the optimal mutation rate by empirically determining what mutation rate produced the highest rate of adaptation. Then, we allowed mutation rates to evolve, and we evaluated the proximity to the optimum. Although we chose conditions favorable for mutation rate optimization, the evolved rates were invariably far below the optimu…

0106 biological sciencesMutation rateTime FactorsDigital organismsFitness landscapeQH301-705.5Biology010603 evolutionary biology01 natural sciencesCellular and Molecular Neuroscience03 medical and health sciences0302 clinical medicineGeneticsComputer SimulationBiology (General)Selection GeneticMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biology0303 health sciencesEvolutionary BiologyNatural selectionEcologyModels GeneticComputational Biology15. Life on landAdaptation PhysiologicalBiological EvolutionComputational Biology/Evolutionary ModelingReplication fidelityAsexual populationsEvolvabilityComputational Theory and MathematicsEvolutionary biologyModeling and SimulationViral evolutionMutation (genetic algorithm)MutationDNA Mismatch repairAdaptationAvida030217 neurology & neurosurgeryResearch Article
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Transformation of agricultural landscapes in the Anthropocene: Nature's contributions to people, agriculture and food security

2020

Fil: Vanbergen, Adam J. Université de Bourgogne Franche-Comté. AgroSup Dijon. Agroécologie. Francia. Fil: Aizen, Marcelo A. Universidad Nacional del Comahue. Instituto de Investigaciones en Biodiversidad y Medioambiente. Rio Negro, Argentina. Fil: Aizen, Marcelo A. Consejo Nacional de Investigaciones Científicas y Técnicas de Argentina. Instituto de Investigaciones en Biodiversidad y Medioambiente. Rio Negro, Argentina. Fil: Cordeau, Stephane. Université de Bourgogne Franche-Comté. AgroSup Dijon. Agroécologie. Francia. Fil: Garibaldi, Lucas A. Universidad Nacional de Río Negro. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Ga…

0106 biological sciencesNatural resource economicsorganicAgricultura (General)010603 evolutionary biology01 natural sciencesnature's contributions to people12. Responsible consumptionecological intensificationBiodiversidad y ConservaciónSustainable agricultureNature-based SolutionsParticipatory managementGlobal ChangeAgricultural productivityEcosystem Servicesglobal changenature-based solutionsClimate-Smartagriculture2. Zero hungerFood securityOrganicbusiness.industry1. No povertyAgriculture04 agricultural and veterinary sciences15. Life on landEcologíasustainabilitySustainabilityclimate-smart13. Climate actionAgricultureNature's Contributions to PeopleSustainability[SDE]Environmental Sciences040103 agronomy & agriculture0401 agriculture forestry and fisheriesFood systemsIPMEcological Intensificationbusinessecosystem servicesLandscape planning
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Evidence for specific, high-affinity binding sites for a proteinaceous elicitor in tobacco plasma membrane

1995

Abstract Binding of cryptogein, a proteinaceous elicitor, was studied on tobacco plasma membrane. The binding of the [125I]cryptogein was saturable, reversible and specific with an apparent Kd of 2 nM. A single class of cryptogein binding sites was found with a sharp optimum pH for binding at about pH 7.0. The high-affinity correlates with cryptogein concentrations required for biological activity in vivo.

0106 biological sciencesNicotiana tabacumBiophysics[SDV.BC]Life Sciences [q-bio]/Cellular Biology01 natural sciencesBiochemistryFungal Proteins03 medical and health sciencesStructural BiologyIn vivoTobaccoGeneticsBinding siteReceptor[SDV.BC] Life Sciences [q-bio]/Cellular BiologyMolecular BiologyComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesBinding SitesbiologyNicotiana tabacumChemistryAlgal ProteinsCell MembraneElicitinBiological activityCell BiologyElicitorbiology.organism_classification3. Good healthElicitorKineticsPlants ToxicMembraneBiochemistryCryptogeinPlasma membraneReceptor010606 plant biology & botany
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A large-scale, higher-level, molecular phylogenetic study of the insect order Lepidoptera (moths and butterflies).

2013

Background Higher-level relationships within the Lepidoptera, and particularly within the species-rich subclade Ditrysia, are generally not well understood, although recent studies have yielded progress. We present the most comprehensive molecular analysis of lepidopteran phylogeny to date, focusing on relationships among superfamilies. Methodology / Principal Findings 483 taxa spanning 115 of 124 families were sampled for 19 protein-coding nuclear genes, from which maximum likelihood tree estimates and bootstrap percentages were obtained using GARLI. Assessment of heuristic search effectiveness showed that better trees and higher bootstrap percentages probably remain to be discovered even …

0106 biological sciencesParaphylyNonsynonymous substitutionEvolutionary GeneticsAnimal EvolutionTineoideaZoologylcsh:MedicineBiologyAnimal PhylogeneticsMoths010603 evolutionary biology01 natural sciences03 medical and health sciencesDitrysiaMonophylyPhylogeneticsMolecular SystematicsEvolutionary ModelingAnimalsEvolutionary Systematicslcsh:ScienceBiologyPhylogeny030304 developmental biologyTaxonomy0303 health sciencesEvolutionary BiologyMultidisciplinaryPopulation Biologylcsh:RComputational Biologybiology.organism_classificationOrganismal EvolutionPhylogeneticsTaxonBombycoideaAnimal Taxonomylcsh:QZoologyButterfliesPopulation GeneticsResearch ArticlePLoS ONE
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Glutathione deficiency of the Arabidopsis mutant pad2-1 affects oxidative stress-related events, defense gene expression and hypersensitive response

2011

L'article original est publié par The American Society of Plant Biologists; International audience; The Arabidopsis (Arabidopsis thaliana) phytoalexin-deficient mutant pad2-1 displays enhanced susceptibility to a broad range of pathogens and herbivorous insects that correlates with deficiencies in the production of camalexin, indole glucosinolates, and salicylic acid (SA). The pad2-1 mutation is localized in the GLUTAMATE-CYSTEINE LIGASE (GCL) gene encoding the first enzyme of glutathione biosynthesis. While pad2-1 glutathione deficiency is not caused by a decrease in GCL transcripts, analysis of GCL protein level revealed that pad2-1 plants contained only 48% of the wild-type protein amoun…

0106 biological sciencesPhysiologyMutantGlutathione reductaseArabidopsisOligosaccharidesPlant Science01 natural scienceschemistry.chemical_compoundAnti-Infective AgentsGene Expression Regulation PlantCamalexinArabidopsis thaliana0303 health sciencesGlutathioneBiochemistryHost-Pathogen InteractionsDisease SusceptibilitySalicylic AcidOxidation-ReductionSignal TransductionHypersensitive responsePhytophthoradisease resistanceBiologyNitric Oxiderespiratory burst oxidase homolog d[SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics03 medical and health sciencesStress PhysiologicalGeneticsPlants Interacting with Other Organismsglutathione reductase030304 developmental biologyPlant DiseasesArabidopsis ProteinsCell MembraneWild typeGlutathioneHydrogen Peroxidebiology.organism_classificationMolecular biologyPlant LeavesOxidative StresschemistryMutationglutathione-s-transferaseIsochorismate synthasebiology.proteinglutamate-cysteine ligaseReactive Oxygen Species010606 plant biology & botany
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RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design.

2011

International audience; Gene silencing through RNA interference (RNAi) has revolutionized the study of gene function, particularly in non-model insects. However, in Lepidoptera (moths and butterflies) RNAi has many times proven to be difficult to achieve. Most of the negative results have been anecdotal and the positive experiments have not been collected in such a way that they are possible to analyze. In this review, we have collected detailed data from more than 150 experiments including all to date published and many unpublished experiments. Despite a large variation in the data, trends that are found are that RNAi is particularly successful in the family Saturniidae and in genes involv…

0106 biological sciencesPhysiology[SDV]Life Sciences [q-bio]Tissue uptakeBioinformatics01 natural sciencesRNA interferenceRNA interferenceDatabases GeneticDelivery methodsCaenorhabditis elegansRegulation of gene expression0303 health sciencesIMMUNE-RESPONSESMANDUCA-SEXTALepidopteraRNA silencingSILKWORM BOMBYX-MORIResearch DesignInsect ProteinsRNA InterferenceMESSENGER-RNAHELICOVERPA-ARMIGERADOUBLE-STRANDED-RNAComputational biologyBiologyLepidoptera genitaliadsRNA properties03 medical and health sciencesBACILLUS-THURINGIENSISSMALL SILENCING RNASGene silencingAnimalsGene SilencingGene030304 developmental biologyRNA Double-StrandedMechanism (biology)fungiBiology and Life SciencesARMYWORM SPODOPTERA-FRUGIPERDAbiology.organism_classificationImmunity Innate010602 entomologyGene Expression RegulationInsect ScienceEpidermisCAENORHABDITIS-ELEGANSGene functionJournal of insect physiology
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Multilocus sequence typing confirms the close genetic inter-relatedness between three distinct flavescence doree phytoplasma strain clusters and grou…

2007

ABSTRACT Vineyards of southern France and northern Italy are affected by the flavescence dorée (FD) phytoplasma, a quarantine pathogen transmitted by the leafhopper of Nearctic origin Scaphoideus titanus . To better trace propagation of FD strains and identify possible passage between the vineyard and wild plant compartments, molecular typing of phytoplasma strains was applied. The sequences of the two genetic loci map and uvrB - degV , along with the sequence of the secY gene, were determined among a collection of FD and FD-related phytoplasmas infecting grapevine, alder, elm, blackberry, and Spanish broom in Europe. Sequence comparisons and phylogenetic analyses consistently indicated the…

0106 biological sciencesPhytoplasmaMolecular Sequence DataAlnus01 natural sciencesApplied Microbiology and BiotechnologyFLAVESCENCE DOREEMALADIE DES PLANTES03 medical and health sciencesPlant MicrobiologyPhylogeneticsMOLLICUTEBotanyPHYTOPLASMEVitisPhylogenyComputingMilieux_MISCELLANEOUS030304 developmental biologyDNA PrimersPlant Diseases2. Zero hungerGenetics[SDV.EE]Life Sciences [q-bio]/Ecology environment0303 health sciencesEcologyPhylogenetic treebiologyBase SequenceJAUNISSEGrapevine yellowsSequence Analysis DNADIVERSITEbiology.organism_classificationScaphoideus titanusLeafhopperEuropeGene ComponentsPhytoplasmaGenes BacterialMultilocus sequence typingFlavescence doréePolymorphism Restriction Fragment Length010606 plant biology & botanyFood ScienceBiotechnology
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Seed germination and seedling allogamy in Rosmarinus officinalis: the costs of inbreeding.

2018

Self‐pollination by geitonogamy is likely in self‐compatible plants that simultaneously expose a large number of flowers to pollinators. However, progeny of these plants is often highly allogamous. Although mechanisms to increase cross‐pollination have been identified and studied, their relative importance has rarely been addressed simultaneously in plant populations. We used Rosmarinus officinalis to explore factors that influence the probability of self‐fertilisation due to geitonogamy or that purge its consequences, focusing on their effects on seed germination and allogamy rate. We experimentally tested the effect of geitonogamy on the proportion of filled seeds and how it influences ge…

0106 biological sciencesPollinationAllogamyGeitonogamyReproductive biologyGerminationPlant ScienceFlowersSelf-FertilizationBiologyAllogamy010603 evolutionary biology01 natural sciencesPopulation densityGeitonogamyPollinatorInbreedingPollinationEcology Evolution Behavior and Systematicsfungifood and beveragesGeneral MedicineQK0900biology.organism_classificationSeed germinationRosmarinusHorticultureGerminationSeedlingSeedlingsSeedsQK0926Hybridization GeneticMale‐sterile flowersInbreeding010606 plant biology & botanyPlant biology (Stuttgart, Germany)
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Town population size and structuring into villages and households drive infectious disease risks in pre-healthcare Finland

2021

Social life is often considered to cost in terms of increased parasite or pathogen risk. However, evidence for this in the wild remains equivocal, possibly because populations and social groups are often structured, which affects the local transmission and extinction of diseases. We test how the structuring of towns into villages and households influenced the risk of dying from three easily diagnosable infectious diseases—smallpox, pertussis and measles—using a novel dataset covering almost all of Finland in the pre-healthcare era (1800–1850). Consistent with previous results, the risk of dying from all three diseases increased with the local population size. However, the division of towns …

0106 biological sciencesPopulationDiseaseCommunicable Diseases010603 evolutionary biology01 natural sciencesMeaslesGeneral Biochemistry Genetics and Molecular BiologySocial group03 medical and health sciencesmedicineHumansSmallpoxCitieseducationFinland030304 developmental biologyGeneral Environmental SciencePopulation Density0303 health scienceseducation.field_of_studyEcologyGeneral Immunology and MicrobiologyTransmission (medicine)Population sizeGeneral Medicinemedicine.diseaseGeographyInfectious disease (medical specialty)General Agricultural and Biological SciencesDelivery of Health CareDemographyProceedings of the Royal Society B: Biological Sciences
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Short-term response of the slow growing seagrass Posidonia oceanica to simulated anchor impact

2007

Experimental evaluations about the impact of anchors of small vessels have previously shown that each anchoring can on average damage up to six shoots of Posidonia oceanica, removing small amount of biomass and, at the same time, interrupting continuity among shoots. The aim of the paper was to investigate the response of P. oceanica to different damage intensity at two levels of substrata compactness. Three treatments were considered: control (no damage); low damage (simulated anchor damage by three strokes of a hoe); and high damage (six strokes). Disturbance was higher where the substratum was highly penetrable and after one year significant variation was observed among treatments for bo…

0106 biological sciencesPotamogetonaceaeTime FactorsAquatic ScienceOceanography010603 evolutionary biology01 natural sciencesBotanyMediterranean Sea14. Life underwaterShipsAnalysis of VarianceBiomass (ecology)AlismatalesbiologyPhenology010604 marine biology & hydrobiologyfood and beveragesGeneral Medicinebiology.organism_classificationPollutionSea grassHorticultureSeagrassItalyPosidonia oceanicaShootSlow GrowingEnvironmental MonitoringMarine Environmental Research
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