Search results for "stream"
showing 10 items of 682 documents
Decreased Proliferation in the Neurogenic Niche, Disorganized Neuroblast Migration, and Increased Oligodendrogenesis in Adult Netrin-5-Deficient Mice.
2020
In the adult mouse brain, neurogenesis mainly occurs in the ventricular-subventricular zone (V-SVZ) and the subgranular zone of the hippocampal dentate gyrus. Neuroblasts generated in the V-SVZ migrate to the olfactory bulb via the rostral migratory stream in response to guidance molecules, such as netrin-1. We previously showed that the related netrin-5 (NTN5) is expressed in Mash1-positive transit-amplifying cells and doublecortin-positive neuroblasts in the granule cell layer of the olfactory bulb, the rostral migratory stream, and the subgranular zone of the adult mouse brain. However, the precise role of NTN5 in adult neurogenesis has not been investigated. In this study, we show that …
Rapid, reproducible transduction of select forebrain regions by targeted recombinant virus injection into the neonatal mouse brain
2009
Viral vectors can mediate long-term gene expression in different regions of the brain. Recombinant adeno-associated virus (rAAV) and Lenti virus (LV) have both gained prominence due to their ability to achieve specific transduction of various neuronal populations. Whilst widespread gene delivery has been obtained by targeted injection of rAAV in various brain structures, LV has also been utilized for infection of stem cell populations for cell lineage tracing. Both viral vector systems are most commonly used for gene delivery in mature brains, but the great potential of somatic gene delivery into the neonate brain has not been systematically exploited. Here we provide a systematic guideline…
Deploying harmonized ITS services in the framework of EasyWay project
2012
In the last decade, the use of new technologies in the transportation domain has made possible the development of the Intelligent Transport System (ITS). However, the ITS services were deployed isolated. The purpose of the EasyWay Project is to involve all the European countries to deploy harmonized ITS services taking into account the European citizen as final In this paper, an introduction of EasyWay project is done, including the ITS concept services and the Deployment Guidelines. A deployment guideline for traffic management and corridors is presented. Using this guideline, a real Spanish Traffic management Plan is analyzed.
Predicting the equilibrium bed slope in natural streams using a stochastic model for incipient sediment motion
2011
In this paper, a method to predict the equilibrium bed slope in natural streams based on the incipient motion criterion is proposed. The method is based on the criterion suggested by Gessler to simulate the grain size distribution of the armour coat using the concept of critical shear stress of a sediment mixture. In particular, a different expression of the probability for a single particle size to be part of the armour coat is firstly proposed; then, a simple two-steps criterion is suggested to estimate the safety factor required by the proposed approach. The method is applied in three different Italian regions (Calabria, Basilicata, and Tuscany) and required several field campaigns invol…
EL G-20, ¿una luz sin sombras?
2009
Beyond Borders in the History of Science Education
2015
In this chapter, I explore the interactions between the new history of science education and the research agenda of the group “Science and Technology in the European Periphery” (STEP). While reviewing the contributions made by STEP members to this field, I discuss some missed opportunities and challenges faced by peripheral contexts in mainstream narratives of the history of science education. Many authors have called for cross-national studies and the application of a comparative approach to the history of science education, but studies of this kind are few. They require researchers to use sources written in several languages and to master a wide range of local studies and highly fragmente…
Teacher satisfaction at the educational placement of students with special educational needs
2016
This study conducted a large-scale survey to investigate the satisfaction of Finnish primary school teachers toward the current educational placement of their students with special educational needs (SEN). Teachers were asked to recommend the most suitable educational placement for each of their SEN students from a pool of six alternatives: a mainstream classroom, part-time special education, a special classroom in the mainstream school, a special school, a state special school, or an institution. Data were obtained from 980 students representing 68 schools. The results showed that, in the majority of cases, teachers recommended a different level to the current level of placement for their …
Hearing-impaired pupils in mainstream education in Finland: teachers’ experiences of inclusion and support
2017
Today, in Finland, the majority of hearing-impaired pupils attend regular schools. This is in line with inclusive policy. This study aims to investigate do these pupils receive support from teacher ...
Sedimentological and deformational criteria for discriminating subglaciofluvial deposits from subaqueous ice-contact fan deposits: A Pleistocene exam…
2014
A pit located near Ballyhorsey, 28 km south of Dublin (eastern Ireland), displays subglacially deposited glaciofluvial sediments passing upwards into proglacial subaqueous ice-contact fan deposits. The coexistence of these two different depositional environments at the same location will help with differentiation between two very similar and easily confused glacial lithofacies. The lowermost sediments show aggrading subglacial deposits indicating a constrained accommodation space, mainly controlled by the position of an overlying ice roof during ice-bed decoupling. These sediments are characterized by vertically stacked tills with large lenses of tabular to channelized sorted sediments. The…
2018
Positive teacher attitudes are essential for success when children with special educational needs (SEN) are placed into mainstream classrooms. The present study surveyed teachers’ attitudes towards...