Search results for "terpenoid"

showing 10 items of 221 documents

Stereochemistry of terpene derivatives. Part 4:☆ Fragrant terpenoid derivatives with an unsaturated gem-dimethylbicyclo[3.1.0]hexane system

2005

Abstract Starting from (+)-3-carene 1 several chiral fragrant compounds with the bicyclo[3.1.0]hexane system 4–6 and 10–20 were synthesized. These compounds are structural analogues of naturally occurring fragrant compounds, such as ionones and damascones, and possess either an endo- or an exo-cyclic double bond in the bicyclo[3.1.0]hexane moiety. The absolute configuration of selected products was confirmed by X-ray crystallography and circular dichroism analysis.

chemistry.chemical_classificationCircular dichroismBicyclic moleculeDouble bondChemistryStereochemistryOrganic ChemistryAbsolute configurationCatalysisTerpenoidInorganic ChemistryTerpeneHexanechemistry.chemical_compoundMoietyOrganic chemistryPhysical and Theoretical ChemistryTetrahedron-Asymmetry
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New Triterpenoid and Ergostane Glycosides from the Leaves of Hydrocotyle umbellata L.

2011

Two new triterpenoid glycosides, together with two new ergostane glycosides, umbellatosides A–D (1–4, resp.), have been isolated from the leaves of Hydrocotyle umbellata L. Their structures were established by 2D-NMR spectroscopic techniques (1H,1H-COSY, TOCSY, NOESY, HSQC, and HMBC) and mass spectrometry as 3β,22β-dihydroxy-3-O-[α-L-rhamnopyranosyl-(12)-β-D-glucuronopyranosyl]olean-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (1), 3-O-[α-L-rhamnopyranosyl-(12)-β-D-glucuronopyranosyl]oleanolic acid 28-O-β-D-glucopyranosyl ester (2), (3β,11α,26)-ergosta-5,24(28)-diene-3,11,26-triol 3-O-(β-D-glucopyranosyl)-11-O-(α-L-rhamnopyranosyl)-26-O-β-D-glucopyranoside (3), and (3β,11α,21,26)-ergosta…

chemistry.chemical_classificationErgostanebiologyStereochemistryOrganic ChemistryGlycosideHydrocotyle umbellataMass spectrometrybiology.organism_classificationBiochemistryCatalysisInorganic ChemistryTerpenechemistry.chemical_compoundTriterpenoidchemistryDrug DiscoveryOrganic chemistryPhysical and Theoretical ChemistryOleanolic acidTwo-dimensional nuclear magnetic resonance spectroscopyHelvetica Chimica Acta
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The Creolophins: A Family of Linear Triquinanes fromCreolophus cirrhatus (Basidiomycete)

2007

Complicatic acid and five novel linear triquinanes were isolated from mycelial cultures of Creolophus cirrhatus. The creolophins A, C, D, and E represent a novel type of highly oxidized triquinane sesquiterpenoids. Whereas those compounds with a secondary alcohol moiety in ring A are stable, the exomethylene ketone creolophin E (5) partly dimerized during workup to form the decacyclic 1,4-dioxepin-6-one neocreolophin (6). Compounds 5 and 6 display cytotoxic activities against several tumor cell lines.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)

chemistry.chemical_classificationKetoneStereochemistryOrganic ChemistryAlcoholTumor cellsNuclear magnetic resonance spectroscopyRing (chemistry)Terpenoidchemistry.chemical_compoundchemistryCreolophus cirrhatusMoietyPhysical and Theoretical ChemistryEuropean Journal of Organic Chemistry
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Acylated triterpene saponins from the roots of Securidaca longepedunculata.

2009

Abstract Four triterpene saponins , 3- O -β- d -glucopyranosylpresenegenin 28- O -β- d -apiofuranosyl-(1 → 3)-β- d -xylopyranosyl-(1 → 4)-[β- d -apiofuranosyl-(1 → 3)]-α- l -rhamnopyranosyl-(1 → 2)-{4- O -[( E )-3,4,5-trimethoxycinnamoyl]}-β- d -fucopyranosyl ester, 3- O -β- d -glucopyranosylpresenegenin 28- O -β- d -apiofuranosyl-(1 → 3)-β- d -xylopyranosyl-(1 → 4)-[β- d -apiofuranosyl-(1 → 3)]-α- l -rhamnopyranosyl-(1 → 2)-[(6- O -acetyl)-β- d -glucopyranosyl-(1 → 3)]-{4- O -[( E )-3,4,5-trimethoxycinnamoyl]}-β- d -fucopyranosyl ester, 3- O -β- d -glucopyranosylpresenegenin 28- O -β- d -apiofuranosyl-(1 → 3)-β- d -xylopyranosyl-(1 → 4)-[β- d -apiofuranosyl-(1 → 3)]-α- l -rhamnopyranosyl-(…

chemistry.chemical_classificationMolecular StructureChemistryStereochemistryPlant ExtractsChemical structureAcylationSaponinSecuridacaPlant ScienceGeneral MedicineHorticultureSaponinsBiochemistryPresenegeninPlant RootsTriterpenesTriterpenoidSecuridaca longepedunculataTriterpeneMolecular BiologyTwo-dimensional nuclear magnetic resonance spectroscopyPhytochemistry
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Preparation of 9a-Fluorinated Sesquiterpenic Drimanes and Evaluation of Their Antifeedant Activities

2010

19 pages, figures, and tables statistics.

chemistry.chemical_classificationNatural productsKetoneStereochemistryTerpenoidsOrganic ChemistryElectrophilic fluorinationBiological activitiesTotal synthesisTotal synthesisFluorineEnolChemical synthesischemistry.chemical_compoundchemistryWittig reactionOrganic chemistryPhysical and Theoretical ChemistryCarbonylationCyanohydrin
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Polyacanthoside A, a new oleanane-type triterpenoid saponin with cytotoxic effects from the leaves of Acacia polyacantha (Fabaceae)

2018

The chemical investigation of the leaves and stem bark of Acacia polyacantha (Fabaceae) led to the isolation of a new oleanane-type triterpenoid saponin named polyacanthoside A 1 together with fifteen known compounds. Their structures were established from spectral , mainly HRESIMS, 1D NMR and 2D NMR and by comparison with literature data. The cytotoxicity of compound 1 and the analogues 8 as well as doxorubicin was determined in a panel of 9 cancer cell lines including sensitive and drug resistant phenotypes. Unlike the analogue 8, compound 1 as well as doxorubicin displayed cytotoxic effects in all the 9 tested cancer cell lines with IC50 values ranged from 8.90 μM (towards CCRF-CEM leuke…

chemistry.chemical_classificationStem barkbiologyTraditional medicine010405 organic chemistryChemistryOrganic ChemistryAcaciaPlant ScienceFabaceaebiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciencesAnalytical Chemistry010404 medicinal & biomolecular chemistrychemistry.chemical_compoundCytotoxic T cell3-O-methyl-D-chiro-inositolOleananeTriterpenoid saponin
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New Triterpene Saponins fromAcanthophyllum pachystegium

2004

Four new triterpenoid saponins, pachystegiosides A (1), B (2), C (3), and D (4), were isolated from the roots of Acanthophyllum pachystegium K. H. Their structures were elucidated by means of a combination of homo- and heteronuclear 2D-NMR techniques (COSY, TOCSY, NOESY, HSQC, and HMBC) and by FAB-MS. The new compounds were characterized as 3-O-{O-β-D-galactopyranosyl-(12)-O-[β-D-xylopyranosyl-(13)]-β-D-glucuronopyranosyl}quillaic acid 28-{O-β-D-xylopyranosyl-(13)-O-β-D-xylopyranosyl-(14)-O-α-L-rhamnopyranosyl-(12)-O-[3,4-di-O-acetyl-β-D-quinovopyranosyl-(14)]-β-D-fucopyranosyl}ester (1), 3-O-{O-β-D-galactopyranosyl-(12)-O-[β-D-xylopyranosyl-(13)]-β-D-glucuronopyranosyl}quillaic acid 28-{O-…

chemistry.chemical_classificationStereochemistryOrganic ChemistryBiochemistryCatalysisInorganic ChemistryQuillaic acidTriterpenoidTriterpenechemistryHeteronuclear moleculeAcanthophyllum pachystegiumDrug DiscoveryPhysical and Theoretical ChemistryTwo-dimensional nuclear magnetic resonance spectroscopyHeteronuclear single quantum coherence spectroscopyHelvetica Chimica Acta
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Triterpenoid saponins from Piptadeniastrum africanum (Hook. f.) Brenan

2013

One new triterpenoid saponin, named piptadeniaoside (1), along with two known saponins (2–3) have been isolated from the stem bark of Piptadeniastrum africanum. After previous isolation of flavone derivatives from this plant, new phytochemical investigations were performed for its saponin content. Their structures were established by direct interpretation of their spectral data, mainly HRESIMS, 1D NMR (1H, 13C NMR, DEPT) and 2D NMR (COSY, NOESY, HSQC and HMBC), and by comparison with the literature data.

chemistry.chemical_classificationTraditional medicineChemistryStereochemistrySaponinPlant ScienceDEPTCarbon-13 NMRBiochemistrychemistry.chemical_compoundPhytochemicalAgronomy and Crop ScienceTwo-dimensional nuclear magnetic resonance spectroscopyOleanolic acidHeteronuclear single quantum coherence spectroscopyBiotechnologyTriterpenoid saponinPhytochemistry Letters
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Vaccinium Genus Berry Waxes and Oils

2019

Vaccinium is a common and widespread genus of about 450 species of shrubs or dwarf shrubs in the heath family (Ericaceae). Most of Vaccinium species produce edible berries and many berries are widely cultivated at an industrial scale, for example, bilberries (Vaccinium myrtillus L.), highbush blueberries (Vaccinium corymbosum L.), lingonberries (Vaccinium vitis-idaea L.), and cranberries (Vaccinium oxycoccos L.). These berries are important articles in the markets of berries in Northern countries both raw, and processed. Vaccinium berries are at first valued considering high vitamin concentrations as well as high concentrations of phenolics. However, also oils and waxes (lipids) of Vacciniu…

chemistry.chemical_classificationWaxVaccinium oxycoccosbiologyBerrybiology.organism_classificationVaccinium myrtillusTerpenoidHorticulturechemistryEricaceaevisual_artvisual_art.visual_art_mediumVacciniumPolyunsaturated fatty acid
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Monoterpenes in grape juice and wines.

2000

The importance of monoterpenes on varietal flavour of wines has been reviewed. These compounds were mainly found linked to sugar moieties in the grape juice and wines, showing no olfactive characteristics. In this way, mechanisms to liberate terpenes were studied, making a comparative study between acidic and enzymic hydrolysis of terpene glycosides. Finally, analytical techniques developed to study these compounds, in both free or glycosidically forms, and also to fractionate glycosidic precursors, have been discussed.

chemistry.chemical_classificationWineChromatographyTerpenesMonoterpeneHydrolysisOrganic ChemistryFlavourfood and beveragesGlycosideGlycosidic bondWineGeneral MedicineBiochemistryTerpenoidAnalytical ChemistryTerpeneBeverageschemistryGlycosidesRosalesSugarJournal of chromatography. A
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