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showing 10 items of 6927 documents

Volatile Components from Aerial Parts of Centaurea diffusa and C. micrantha ssp. melanosticta and Their Biocidal Activity on Microorganisms Affecting…

2018

The chemical composition of the essential oils from aerial parts of two taxa of Centaurea belonging to subgenus Acrolophus, Centaurea diffusa Lam. and C. micrantha Hoff. ssp. melanosticta (Lange) Dostàl, respectively collected in Croatia and Spain, were evaluated by GC and GC-MS. The main components of C. diffusa were hexadecanoic acid (31.1%), ( Z,Z)-9,12-octadecadienoic acid (10.7%) and damascenone isomers (6.4%), whereas hexahydrofarnesyl acetone (27.8%), hexadecanoic acid (8.3%) and caryophyllene oxide (6.4%) were the most abundant components of C. micrantha ssp. melanosticta. The oils showed good antibacterial and antifungal activities against some microorganisms that infest historica…

0106 biological sciencesPharmacologybiology010405 organic chemistryMicroorganismAcrolophusMicranthaPlant ScienceGeneral MedicineAsteraceaebiology.organism_classification010603 evolutionary biology01 natural sciencesCentaurea diffusa0104 chemical sciencesTaxonComplementary and alternative medicineCentaureaDrug DiscoveryBotanySubgenusNatural Product Communications
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Guaianolides from the Aerial Parts of Centaurea Hololeuca

2006

Seven guaianolides were isolated from the acetone extract of the aerial parts of Centaurea hololeuca Boiss. The antifeedant activity of the natural compounds (1–7) and of four chloro derivatives (8–11), synthesized from repin (1) and janerin (3) were tested against larvae of Spodoptera littoralis. Cebellin J (6) and chlorojanerin (11) showed significant antifeedant activity at 100 ppm, whereas at this concentration cebellin G (4) and 15-deschloro-15-hydroxychlorojanerin (7) stimulated feeding. Cebellin G (4) stimulated larvae of S. littoralis to feed at low concentration, but deterred feeding at high concentrations. The addition of chlorine to repin (1) resulted in an increase in antifeeda…

0106 biological sciencesPharmacologybiologyChemistryPlant ScienceGeneral Medicinebiology.organism_classification010603 evolutionary biology01 natural sciencesComplementary and alternative medicineCentaureaDrug DiscoveryBotany010606 plant biology & botanyNatural Product Communications
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Mycotheca of Edible and Medicinal Mushrooms at Herbarium SAF as a Potential Source of Nutraceuticals and Cultivated Mushrooms

2018

Basidiomycetes strains (n = 39) belonging to 9 genera in 8 families are kept in the mycotheca of the Department of Agricultural, Food and Forest Sciences at the University of Palermo (Palermo, Italy). All of the strains are medicinal mushrooms, and some are of great commercial and nutraceutical interest.

0106 biological sciencesPharmacologybusiness.industryBasidiomycota010604 marine biology & hydrobiologyAgricultureBiology010603 evolutionary biology01 natural sciencesApplied Microbiology and BiotechnologyNutraceuticalHerbariumItalyAgricultureDietary SupplementsDrug DiscoveryBotanyHumansPotential sourceFruiting Bodies FungalbusinessInternational Journal of Medicinal Mushrooms
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RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design.

2011

International audience; Gene silencing through RNA interference (RNAi) has revolutionized the study of gene function, particularly in non-model insects. However, in Lepidoptera (moths and butterflies) RNAi has many times proven to be difficult to achieve. Most of the negative results have been anecdotal and the positive experiments have not been collected in such a way that they are possible to analyze. In this review, we have collected detailed data from more than 150 experiments including all to date published and many unpublished experiments. Despite a large variation in the data, trends that are found are that RNAi is particularly successful in the family Saturniidae and in genes involv…

0106 biological sciencesPhysiology[SDV]Life Sciences [q-bio]Tissue uptakeBioinformatics01 natural sciencesRNA interferenceRNA interferenceDatabases GeneticDelivery methodsCaenorhabditis elegansRegulation of gene expression0303 health sciencesIMMUNE-RESPONSESMANDUCA-SEXTALepidopteraRNA silencingSILKWORM BOMBYX-MORIResearch DesignInsect ProteinsRNA InterferenceMESSENGER-RNAHELICOVERPA-ARMIGERADOUBLE-STRANDED-RNAComputational biologyBiologyLepidoptera genitaliadsRNA properties03 medical and health sciencesBACILLUS-THURINGIENSISSMALL SILENCING RNASGene silencingAnimalsGene SilencingGene030304 developmental biologyRNA Double-StrandedMechanism (biology)fungiBiology and Life SciencesARMYWORM SPODOPTERA-FRUGIPERDAbiology.organism_classificationImmunity Innate010602 entomologyGene Expression RegulationInsect ScienceEpidermisCAENORHABDITIS-ELEGANSGene functionJournal of insect physiology
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Town population size and structuring into villages and households drive infectious disease risks in pre-healthcare Finland

2021

Social life is often considered to cost in terms of increased parasite or pathogen risk. However, evidence for this in the wild remains equivocal, possibly because populations and social groups are often structured, which affects the local transmission and extinction of diseases. We test how the structuring of towns into villages and households influenced the risk of dying from three easily diagnosable infectious diseases—smallpox, pertussis and measles—using a novel dataset covering almost all of Finland in the pre-healthcare era (1800–1850). Consistent with previous results, the risk of dying from all three diseases increased with the local population size. However, the division of towns …

0106 biological sciencesPopulationDiseaseCommunicable Diseases010603 evolutionary biology01 natural sciencesMeaslesGeneral Biochemistry Genetics and Molecular BiologySocial group03 medical and health sciencesmedicineHumansSmallpoxCitieseducationFinland030304 developmental biologyGeneral Environmental SciencePopulation Density0303 health scienceseducation.field_of_studyEcologyGeneral Immunology and MicrobiologyTransmission (medicine)Population sizeGeneral Medicinemedicine.diseaseGeographyInfectious disease (medical specialty)General Agricultural and Biological SciencesDelivery of Health CareDemographyProceedings of the Royal Society B: Biological Sciences
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Aflatoxins and A. flavus Reduction in Loaf Bread through the Use of Natural Ingredients

2018

In this study, the antifungal activity of yellow mustard (YMF) and oriental mustard (OMF) meal extracts against 14 strains of fungi was tested on a solid medium. The results obtained with the YMF were next confirmed in liquid medium determining the minimum inhibitory concentration (MIC) and the minimum fungicide concentration (MFC). Finally, the use of YMF as a natural preservative to extend the useful life of bread was evaluated. Breads with different concentrations of YMF (2, 4, 6 and 8 g/kg) were prepared and contaminated with Aspergillus flavus ISPA 8111 and Penicillium nordicum CECT 2320. For 10 days the formation of mycelium was observed, and after that the fungal growth and the mycot…

0106 biological sciencesPreservativeAflatoxinaflatoxinsAntifungal AgentsMustard CompoundsPharmaceutical ScienceAspergillus flavusMicrobial Sensitivity TestsShelf life01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistry010608 biotechnologyDrug DiscoveryFood sciencePhysical and Theoretical ChemistryLC-MS/MSMycotoxinMyceliumMolecular Structurebiologymycotoxin reductionOrganic Chemistrydigestive oral and skin physiologyPenicilliumfood and beveragesBread04 agricultural and veterinary sciencesbiology.organism_classification040401 food sciencemustard flourFungicideFood StoragechemistryChemistry (miscellaneous)Sodium propionateFood MicrobiologyFood PreservativesMolecular Medicineshelf lifePropionatesAspergillus flavusMolecules
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An overview of natural antimicrobials role in food

2017

The present paper aims to review the natural food preservatives with antimicrobial properties emphasizing their importance for the future of food manufacturing and consumers' health. The extraction procedures applied to natural antimicrobials will be considered, followed by the description of some natural preservatives' antimicrobial mechanism of action, including (i) membrane rupture with ATP-ase activity inhibition, (ii) leakage of essential biomolecules from the cell, (iii) disruption of the proton motive force and (iiii) enzyme inactivation. Moreover, a provenance-based classification of natural antimicrobials is discussed by considering the sources of origin for the major natural prese…

0106 biological sciencesPreservativeFood industryAntimicrobial peptidesMicrobial Sensitivity Tests01 natural sciences0404 agricultural biotechnologyMicrobial resistanceAnti-Infective AgentsParasitic Sensitivity Tests010608 biotechnologyDrug DiscoveryAgrártudományokAnimalsHumansParasitesPharmacologyBiological ProductsBacteriaÉlelmiszertudományokChemistrybusiness.industryActivity inhibitionOrganic ChemistryFungi04 agricultural and veterinary sciencesGeneral MedicineAntimicrobialFood safetyBiopreservation040401 food scienceBiotechnologyFood PreservativesbusinessEuropean Journal of Medicinal Chemistry
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NMR structure determination of (11E)-trinervita-1(14),2,11-triene, a new diterpene from sexual glands of termites

2005

Graphical Abstract Full-size image; International audience; Female alates of Nasutitermes ephratae termites from Guadeloupe and Nasutitermes sp. from Brazil produce a diterpene hydrocarbon of the molecular formula C20H30 as the main component of their tergal gland secretion. Analysis of NMR, IR, and mass spectra of the diterpene led to a structure of (11E)-trinervita-1(14),2,11-triene. Based on a comparison with the published oxygenated trinervitane skeleton from termites we prefer the enantiomer with absolute configurations (4R,7S,8R,15S,16S). The suggested structure is supported by ab initio quantum chemical calculation of 1H and 13C chemical shifts for the optimized geometry of the molec…

0106 biological sciencesStereochemistryAb initio1H and 13C010402 general chemistry01 natural sciencesBiochemistry1H-RMN; 13C-RMNTerpene03 medical and health scienceschemistry.chemical_compoundDrug Discovery[SDV.IDA]Life Sciences [q-bio]/Food engineeringNasutitermesOrganic chemistryMoleculeDITERPENE HYDROCARBONPHEROMONE[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringGLANDE TERGALE FEMELLEDITERPENIQUE030304 developmental biologyFEMALE TERGAL GLANDchemistry.chemical_classification0303 health sciencesbiology010405 organic chemistryChemical shiftOrganic ChemistryTERMITEGeneral Medicinebiology.organism_classification0104 chemical sciences010602 entomologyHydrocarbonchemistryTRINERVITANEMass spectrumEnantiomerDiterpene
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New Acyclic Cytotoxic Jasplakinolide Derivative from the Marine Sponge Jaspis splendens

2019

A new acylic jasplakinolide congener (2), another acyclic derivative requiring revision (4), together with two jasplakinolide derivatives including the parent compound jasplakinolide (1) were isolated from the Indonesian marine sponge Jaspis splendens. The chemical structures of the new and known compounds were unambiguously elucidated based on HRESIMS and exhaustive 1D and 2D NMR spectral analysis as well as a comparison of their NMR data with those of jasplakinolide (1). The isolated jasplakinolides inhibited the growth of mouse lymphoma (L5178Y) cells in vitro with IC50 values in the low micromolar to nanomolar range.

0106 biological sciencesStereochemistryPharmaceutical Science01 natural sciencesjasplakinolide Z<sub>5</sub>Drug Discovery<i>Jaspis splendens</i>Ic50 valuesCytotoxic T cellSpectral analysisPharmacology Toxicology and Pharmaceutics (miscellaneous)lcsh:QH301-705.5cytotoxic activitybiology010405 organic chemistryChemistry010604 marine biology & hydrobiologyMouse LymphomaJaspis splendensbiology.organism_classificationIn vitro0104 chemical sciencesSpongelcsh:Biology (General)Two-dimensional nuclear magnetic resonance spectroscopyjasplakinolide Z<sub>6</sub>Marine Drugs
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Five centuries of cod catches in Eastern Canada

2021

Abstract The fishery for Northern Atlantic cod (Gadus morhua) off Newfoundland and Labrador, Eastern Canada, presents the most spectacular case of an exploited stock crashed in a few decades by an industrial bottom trawl fishery under a seemingly sophisticated management regime after half a millennium of sustainable fishing. The fishery, which had generated annual catches of 100000 to 200000 tonnes from the beginning of the 16th century to the 1950s,  peaked in 1968 at 810000 tonnes, followed by a devastating collapse and closure 24 years later. Since then, stock recovery may have been hindered by premature openings, with vessels targeting the remains of the cod population. Previous researc…

0106 biological sciencesStock Recoveryeducation.field_of_studyStock assessmentEcologybiology010604 marine biology & hydrobiologyPopulationFishingVDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480::Marinbiologi: 497Aquatic ScienceOceanographybiology.organism_classification010603 evolutionary biology01 natural sciencesFisheryGeographyShifting baselineGadus14. Life underwatereducationAtlantic codEcology Evolution Behavior and SystematicsStock (geology)ICES Journal of Marine Science
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