0000000000077117

AUTHOR

Nicolas Chopin

Discussion of "modern statistics of spatial point processes"

The paper ‘Modern statistics for spatial point processes' by Jesper Møller and Rasmus P. Waagepetersen is based on a special invited lecture given by the authors at the 21st Nordic Conference on Mathematical Statistics, held at Rebild, Denmark, in June 2006. At the conference, Antti Penttinen and Eva B. Vedel Jensen were invited to discuss the paper. We here present the comments from the two invited discussants and from a number of other scholars, as well as the authors' responses to these comments. Below Figure 1, Figure 2, etc., refer to figures in the paper under discussion, while Figure A, Figure B, etc., refer to figures in the current discussion. All numbered sections and formulas ref…

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Sequential Monte Carlo Methods in Random Intercept Models for Longitudinal Data

Longitudinal modelling is common in the field of Biostatistical research. In some studies, it becomes mandatory to update posterior distributions based on new data in order to perform inferential process on-line. In such situations, the use of posterior distribution as the prior distribution in the new application of the Bayes’ theorem is sensible. However, the analytic form of the posterior distribution is not always available and we only have an approximated sample of it, thus making the process “not-so-easy”. Equivalent inferences could be obtained through a Bayesian inferential process based on the set that integrates the old and new data. Nevertheless, this is not always a real alterna…

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On resampling schemes for particle filters with weakly informative observations

We consider particle filters with weakly informative observations (or `potentials') relative to the latent state dynamics. The particular focus of this work is on particle filters to approximate time-discretisations of continuous-time Feynman--Kac path integral models -- a scenario that naturally arises when addressing filtering and smoothing problems in continuous time -- but our findings are indicative about weakly informative settings beyond this context too. We study the performance of different resampling schemes, such as systematic resampling, SSP (Srinivasan sampling process) and stratified resampling, as the time-discretisation becomes finer and also identify their continuous-time l…

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Sequential Monte Carlo methods in Bayesian joint models for longitudinal and time-to-event data

The statistical analysis of the information generated by medical follow-up is a very important challenge in the field of personalized medicine. As the evolutionary course of a patient's disease progresses, his/her medical follow-up generates more and more information that should be processed immediately in order to review and update his/her prognosis and treatment. Hence, we focus on this update process through sequential inference methods for joint models of longitudinal and time-to-event data from a Bayesian perspective. More specifically, we propose the use of sequential Monte Carlo (SMC) methods for static parameter joint models with the intention of reducing computational time in each…

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