0000000000085941
AUTHOR
Nielsen J
Three-prong τ decays with charged kaons
Final states with charged kaons in three-prong τ decays are studied by exploiting the particle identification from the dE/dx measurement. The results are based on a sample of about 1.6 × 105 detected τ pairs collected with the ALEPH detector between 1991 and 1995 around the Z peak. The following branching ratios have been measured: B(τ- → K−K+π−ντ) = (1.63 ± 0.21 ± 0.17) × 10−3, B(τ− → K−π+π−ντ) = (2.14 ± 0.37 ± 0.29) × 10−3, B(τ− → K−K+π−π0ντ) = (0.75 ± 0.29 ± 0.15) × 10−3, and B(τ− → K−π+π−π0ντ) = (0.61 ± 0.39 ± 0.18) × 10−3. The first two measurements are more precise than the current world averages, while the last two channels are investigated for the first time. The 95% C.L. upper limi…
Study of the fragmentation of b quarks into B mesons at the Z peak
The fragmentation of b quarks into B mesons is studied with four million hadronic Z decays collected by the ALEPH experiment during the years 1991-1995. A semi-exclusive reconstruction of B->l nu D(*) decays is performed, by combining lepton candidates with fully reconstructed D(*) mesons while the neutrino energy is estimated from the missing energy of the event. The mean value of xewd, the energy of the weakly-decaying B meson normalised to the beam energy, is found to be mxewd = 0.716 +- 0.006 (stat) +- 0.006 (syst) using a model-independent method; the corresponding value for the energy of the leading B meson is mxel = 0.736 +- 0.006 (stat) +- 0.006 (syst). The reconstructed spectra …
Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries
Background: To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS recruited into the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG-SAFE) study. Methods: This is a secondary analysis of LUNG-SAFE, an international, multicenter, prospective cohort study of patients receiving invasive or noninvasive ventilation in 50 countries spanning 5 continents. The study was carried out over 4 weeks consecutively in the winter of 2014, and 459 ICUs participated. We evaluated the clinical characteris…
Spontaneous Breathing in Early Acute Respiratory Distress Syndrome
Supplemental Digital Content is available in the text.
Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database
Background: Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARDS in critically ill patients with acute hypoxemic respiratory failure (AHRF). Methods: An ancillary analysis of a global, multi-centre prospective observational study (LUNG SAFE) was undertaken. LUNG SAFE evaluated all patients admitted to an intensive care unit (ICU) over a 4-week period, that required mechanical ventilation and met AHRF criteria. Patients who had their AHRF…
Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study
Rationale: Noninvasive ventilation (NIV) is increasingly used in patients with acute respiratory distress syndrome (ARDS). The evidence supporting NIV use in patients with ARDS remains relatively sparse.Objectives: To determine whether, during NIV, the categorization of ARDS severity based on the PaO2/FiO2 Berlin criteria is useful.Methods: The LUNG SAFE (Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure) study described the management of patients with ARDS. This substudy examines the current practice of NIV use in ARDS, the utility of the PaO2/FiO2 ratio in classifying patients receiving NIV, and the impact of NIV on outcome.Measurements and Main…
Measurement of triple gauge WWγ couplings at LEP2 using photonic events
A study of events with photons and missing energy has been performed with the data sample obtained with the ALEPH detector at centre-of-mass energies from 161 to 184 GeV,corresponding to a total integrated luminosity of about 80 pb**-1.The measured distributions are in agreement with Standard Model predictions, leading to constraints on W W gamma gauge coupling parameters Delta(kappa_gamma) and lambda_gamma. The results from the fit to the cross sectionsand to the energy and angular distributions of the photons are: Delta(kappa_gamma) = 0.05 +1.15/-1.10 (stat) +/- 0.25 (syst) lambda_gamma = 0.05 +1.55/-1.45 (stat) +/- 0.30 (syst) A study of events with photons and missing energy has been pe…
Search for Single Top Production in $e^{+} e^{-}$ Collisions at $\sqrt{s}$ up to 209 GeV
Single top production via the flavour changing neutral current reactions e+e- -> \bar{t}c, \bar{t}u is searched for within the 214 pb-1 of data collected by ALEPH at centre-of-mass energies between 204 and 209 GeV. No deviation from the Standard Model expectation is observed and upper limits on the single top production cross sections are derived. The combination with data collected at lower centre-of-mass energies yields an upper limit on the branching ratio BR(t -> Zc)+BR(t -> Zu) 14%, for BR(t -> ��c)+BR(t -> ��u)= 0 and mt=174 GeV/c2.
Variable impact on mortality of AIDS-defining events diagnosed during combination antiretroviral therapy : not all AIDS-defining conditions are created equal
Contains fulltext : 80963.pdf (Publisher’s version ) (Open Access) BACKGROUND: The extent to which mortality differs following individual acquired immunodeficiency syndrome (AIDS)-defining events (ADEs) has not been assessed among patients initiating combination antiretroviral therapy. METHODS: We analyzed data from 31,620 patients with no prior ADEs who started combination antiretroviral therapy. Cox proportional hazards models were used to estimate mortality hazard ratios for each ADE that occurred in >50 patients, after stratification by cohort and adjustment for sex, HIV transmission group, number of antiretroviral drugs initiated, regimen, age, date of starting combination antiretrovir…