0000000000085941

AUTHOR

Nielsen J

showing 9 related works from this author

Three-prong τ decays with charged kaons

1998

Final states with charged kaons in three-prong τ decays are studied by exploiting the particle identification from the dE/dx measurement. The results are based on a sample of about 1.6 × 105 detected τ pairs collected with the ALEPH detector between 1991 and 1995 around the Z peak. The following branching ratios have been measured: B(τ- → K−K+π−ντ) = (1.63 ± 0.21 ± 0.17) × 10−3, B(τ− → K−π+π−ντ) = (2.14 ± 0.37 ± 0.29) × 10−3, B(τ− → K−K+π−π0ντ) = (0.75 ± 0.29 ± 0.15) × 10−3, and B(τ− → K−π+π−π0ντ) = (0.61 ± 0.39 ± 0.18) × 10−3. The first two measurements are more precise than the current world averages, while the last two channels are investigated for the first time. The 95% C.L. upper limi…

PhysicsSystematic errorTime projection chamberPhysics and Astronomy (miscellaneous)010308 nuclear & particles physicsBranching fractionHigh Energy Physics::PhenomenologySettore FIS/01 - Fisica SperimentaleVECTOR01 natural sciencesMESONSParticle identificationPHYSICS0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]High Energy Physics::ExperimentAtomic physics010306 general physicsEngineering (miscellaneous)Particle Physics - Experiment
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Study of the fragmentation of b quarks into B mesons at the Z peak

2001

The fragmentation of b quarks into B mesons is studied with four million hadronic Z decays collected by the ALEPH experiment during the years 1991-1995. A semi-exclusive reconstruction of B->l nu D(*) decays is performed, by combining lepton candidates with fully reconstructed D(*) mesons while the neutrino energy is estimated from the missing energy of the event. The mean value of xewd, the energy of the weakly-decaying B meson normalised to the beam energy, is found to be mxewd = 0.716 +- 0.006 (stat) +- 0.006 (syst) using a model-independent method; the corresponding value for the energy of the leading B meson is mxel = 0.736 +- 0.006 (stat) +- 0.006 (syst). The reconstructed spectra …

QuarkNuclear and High Energy PhysicsParticle physicsMesonElectron–positron annihilationNuclear TheoryHadronFOS: Physical sciences7. Clean energy01 natural sciencesHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]B mesonNuclear Experiment010306 general physicsALEPH experimentPhysicsMissing energy010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyHigh Energy Physics::ExperimentParticle Physics - ExperimentLeptonPhysics Letters B
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Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries

2018

Background: To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS recruited into the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG-SAFE) study. Methods: This is a secondary analysis of LUNG-SAFE, an international, multicenter, prospective cohort study of patients receiving invasive or noninvasive ventilation in 50 countries spanning 5 continents. The study was carried out over 4 weeks consecutively in the winter of 2014, and 459 ICUs participated. We evaluated the clinical characteris…

MaleARDSInternationality[SDV]Life Sciences [q-bio]humanoslnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]traqueostomíaCritical Care and Intensive Care MedicineSeverity of Illness IndexCohort StudiesPropensity-matched analysi0302 clinical medicineTracheostomyestudios prospectivosEpidemiologyAcute respiratory distress syndrome (ARDS)030212 general & internal medicineProspective Studiespuntuación de propensión10. No inequalityProspective cohort studyestudios de cohortesmediana edadancianoRespiratory Distress SyndromerespiraciónRespirationlcsh:Medical emergencies. Critical care. Intensive care. First aidMiddle Aged3. Good healthIntensive Care UnitsCohortArtificialCritical IllneFemaleAcute respiratory distress syndrome (ARDS); ICU; Propensity-matched analysis; Tracheostomy; Ventilation; Aged; Cohort Studies; Critical Illness; Female; Humans; Intensive Care Units; Internationality; Male; Middle Aged; Propensity Score; Prospective Studies; Respiration Artificial; Respiratory Distress Syndrome Adult; Severity of Illness Index; TracheostomyCohort studyHumanAdultmedicine.medical_specialtyCritical IllnessIntensive Care UnitSocio-culturaleunidades de cuidados intensivosenfermedad críticaPropensity-matched analysis03 medical and health sciencesAcute respiratory distress syndrome (ARDS); ICU; Propensity-matched analysis; Tracheostomy; VentilationSeverity of illnessSettore MED/41 - ANESTESIOLOGIAmedicineHumansíndice de gravedad de la enfermedadPropensity ScoreAgedbusiness.industryResearchRespiratory Distress Syndrome Adultinternacionalidadlcsh:RC86-88.9medicine.diseaseR1Respiration ArtificialVentilationProspective Studie030228 respiratory systemPropensity score matchingEmergency medicineICUObservational studyCohort Studiebusiness
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Spontaneous Breathing in Early Acute Respiratory Distress Syndrome

2019

Supplemental Digital Content is available in the text.

MaleRespiratory ratemedicine.medical_treatmentlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Clinical InvestigationsRespiration Artificial/methodsmechanical ventilationCritical Care and Intensive Care MedicineNOPositive-Pressure Respiration03 medical and health sciences0302 clinical medicineacute respiratory distress syndrome controlled mechanical ventilation spontaneous breathing supported ventilationRespiratory RatemedicineHumansProspective StudiesProspective cohort studyArtificial/methodsMechanical ventilationRespiratory Distress Syndromebusiness.industryRespirationConfounding030208 emergency & critical care medicineOdds ratioTidal Wavesacute respiratory distress syndromeMiddle AgedRespiration Artificial3. Good healthcontrolled mechanical ventilationTreatment Outcome030228 respiratory systemAnesthesiasupported ventilationBreathingComputingMethodologies_DOCUMENTANDTEXTPROCESSINGspontaneous breathingRespiratory Distress Syndrome Adult/physiopathologyObservational studyARDSFemaleAdult/physiopathologybusinessRespiratory InsufficiencyCohort studyCritical Care Medicine
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Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis o…

2018

Background: Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARDS in critically ill patients with acute hypoxemic respiratory failure (AHRF). Methods: An ancillary analysis of a global, multi-centre prospective observational study (LUNG SAFE) was undertaken. LUNG SAFE evaluated all patients admitted to an intensive care unit (ICU) over a 4-week period, that required mechanical ventilation and met AHRF criteria. Patients who had their AHRF…

AdultMaleDiabetes mellituLUNG SAFEOrgan Dysfunction Scoreshumanoslnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Socio-culturaleOrgan Dysfunction ScoreDiabetes ComplicationsDiabetes mellituspuntuaciones de disfunción orgánicaRisk FactorsDiabetes Complicationestudios prospectivosHumansfactores de riesgoProspective StudiesHospital MortalityHypoxiamediana edadAcute hypoxemic respiratory failureAgedRespiratory Distress SyndromeancianoAcute respiratory distress syndromeResearchRespirationrespiraciónRespiratory Distress Syndrome Adultlcsh:Medical emergencies. Critical care. Intensive care. First aidlcsh:RC86-88.9Middle AgedRespiration Artificialinsuficiencia respiratoriaAcute hypoxemic respiratory failure; Acute respiratory distress syndrome; Diabetes mellitus; LUNG SAFEProspective StudieArtificialAcute hypoxemic respiratory failure; Acute respiratory distress syndrome; Diabetes mellitus; LUNG SAFE; Aged; Diabetes Complications; Diabetes Mellitus; Female; Hospital Mortality; Humans; Hypoxia; Male; Middle Aged; Organ Dysfunction Scores; Prospective Studies; Respiration Artificial; Respiratory Distress Syndrome Adult; Respiratory Insufficiency; Risk FactorsFemaleRespiratory Insufficiencymortalidad hospitalariacomplicaciones de la diabetesHuman
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Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study

2016

Rationale: Noninvasive ventilation (NIV) is increasingly used in patients with acute respiratory distress syndrome (ARDS). The evidence supporting NIV use in patients with ARDS remains relatively sparse.Objectives: To determine whether, during NIV, the categorization of ARDS severity based on the PaO2/FiO2 Berlin criteria is useful.Methods: The LUNG SAFE (Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure) study described the management of patients with ARDS. This substudy examines the current practice of NIV use in ARDS, the utility of the PaO2/FiO2 ratio in classifying patients receiving NIV, and the impact of NIV on outcome.Measurements and Main…

MaleARDSprocedureblood oxygen tensionCritical Care and Intensive Care MedicineSeverity of Illness Indexlaw.invention0302 clinical medicinelawHospital MortalityRespiratory Distress SyndromeAcute respiratory distress syndromeadult respiratory distress syndromeMiddle AgedIntensive care unitIntensive Care Unitsmedicine.anatomical_structureTreatment Outcomepriority journalpositive end expiratory pressureNoninvasive ventilationdisease severityFemaletreatment outcome AgedNoninvasive ventilationprospective studyHumanAdultPulmonary and Respiratory Medicinemedicine.medical_specialtycohort analysiIntensive Care Unitdisease classificationAcute respiratory distressArticleNO03 medical and health sciencesacute respiratory distress syndrome; noninvasive ventilationlength of staySeverity of illnessSettore MED/41 - ANESTESIOLOGIAmedicineSequential Organ Failure Assessment ScoreHumansIn patientAcute respiratory distress syndrome; Noninvasive ventilation; Aged; Female; Hospital Mortality; Humans; Intensive Care Units; Male; Middle Aged; Respiratory Distress Syndrome Adult; Severity of Illness Index; Treatment Outcome; Noninvasive Ventilation; Pulmonary and Respiratory Medicine; Critical Care and Intensive Care MedicineIntensive care medicineoutcome assessmentAgedLungbusiness.industryRespiratory Distress Syndrome Adult030208 emergency & critical care medicinemedicine.diseasemajor clinical studymortalityrespiratory tract diseasesbreathing ratemulticenter study030228 respiratory systemincidenceObservational studyobservational studybusinessAcute respiratory distress syndrome; Noninvasive ventilation;
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Measurement of triple gauge WWγ couplings at LEP2 using photonic events

1998

A study of events with photons and missing energy has been performed with the data sample obtained with the ALEPH detector at centre-of-mass energies from 161 to 184 GeV,corresponding to a total integrated luminosity of about 80 pb**-1.The measured distributions are in agreement with Standard Model predictions, leading to constraints on W W gamma gauge coupling parameters Delta(kappa_gamma) and lambda_gamma. The results from the fit to the cross sectionsand to the energy and angular distributions of the photons are: Delta(kappa_gamma) = 0.05 +1.15/-1.10 (stat) +/- 0.25 (syst) lambda_gamma = 0.05 +1.55/-1.45 (stat) +/- 0.30 (syst) A study of events with photons and missing energy has been pe…

PhysicsNuclear and High Energy PhysicsParticle physicsMissing energyPhotonLuminosity (scattering theory)Astrophysics::High Energy Astrophysical PhenomenaElectron–positron annihilationLEPGauge (firearms)LambdaStandard ModelALEPH Experimenttriple gauge WWgammaNuclear physicsALEPH Experiment; LEP; triple gauge WWgammaHigh Energy Physics::ExperimentAstrophysics::Earth and Planetary AstrophysicsNuclear ExperimentALEPH experimentParticle Physics - ExperimentPhysics Letters B
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Search for Single Top Production in $e^{+} e^{-}$ Collisions at $\sqrt{s}$ up to 209 GeV

2002

Single top production via the flavour changing neutral current reactions e+e- -> \bar{t}c, \bar{t}u is searched for within the 214 pb-1 of data collected by ALEPH at centre-of-mass energies between 204 and 209 GeV. No deviation from the Standard Model expectation is observed and upper limits on the single top production cross sections are derived. The combination with data collected at lower centre-of-mass energies yields an upper limit on the branching ratio BR(t -> Zc)+BR(t -> Zu) 14%, for BR(t -> ��c)+BR(t -> ��u)= 0 and mt=174 GeV/c2.

PhysicsParticle physicsNuclear and High Energy PhysicsNeutral current010308 nuclear & particles physicsBranching fractionElectron–positron annihilationFOS: Physical sciences01 natural sciencesHigh Energy Physics - ExperimentStandard ModelNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Production (computer science)010306 general physicsParticle Physics - Experiment
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Variable impact on mortality of AIDS-defining events diagnosed during combination antiretroviral therapy : not all AIDS-defining conditions are creat…

2009

Contains fulltext : 80963.pdf (Publisher’s version ) (Open Access) BACKGROUND: The extent to which mortality differs following individual acquired immunodeficiency syndrome (AIDS)-defining events (ADEs) has not been assessed among patients initiating combination antiretroviral therapy. METHODS: We analyzed data from 31,620 patients with no prior ADEs who started combination antiretroviral therapy. Cox proportional hazards models were used to estimate mortality hazard ratios for each ADE that occurred in >50 patients, after stratification by cohort and adjustment for sex, HIV transmission group, number of antiretroviral drugs initiated, regimen, age, date of starting combination antiretrovir…

MaleInfectious diseases and international health [NCEBP 13]Lymphoma030312 virologyEsophageal candidiasisCohort Studies0302 clinical medicineInterquartile range030212 general & internal medicineAIDS-RelatedLymphoma AIDS-Related0303 health sciencesMortality rateProgressive multifocal leukoencephalopathyHazard ratioPrognosis3. Good healthPathogenesis and modulation of inflammation [N4i 1]Infectious DiseasesCombinationDrug Therapy CombinationFemaleInfection and autoimmunity [NCMLS 1]HumanMicrobiology (medical)Adultmedicine.medical_specialtyPrognosiAnti-HIV Agentsantiretroviral therapyInfectious DiseaseArticleAIDS-Related Opportunistic Infection03 medical and health sciencesAcquired immunodeficiency syndrome (AIDS)Drug TherapyInternal medicinemedicineHumansAIDS-defining eventProportional Hazards ModelsAIDS-Related Opportunistic Infections/diagnosis/ mortality; Acquired Immunodeficiency Syndrome/complications/diagnosis/drug; therapy/ mortality; Adult; Anti-HIV Agents/ therapeutic use; Cohort Studies; Drug Therapy; Combination; Female; Humans; Lymphoma; AIDS-Related/diagnosis/mortality; Male; Prognosis; Proportional Hazards ModelsAcquired Immunodeficiency SyndromeAIDS-Related Opportunistic Infectionsbusiness.industryProportional hazards modelPoverty-related infectious diseases [N4i 3]Anti-HIV Agentmedicine.diseasemortalityConfidence intervalImmunologyProportional Hazards ModelCohort Studiebusiness
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