0000000000108366

AUTHOR

Patrizia Toia

showing 51 related works from this author

A Novel Expert System for Non-Invasive Liver Iron Overload Estimation in Thalassemic Patients

2014

Expert Systems can integrate logic based often on computational intelligence methods and they are used in complex problem solving. In this work an Expert System for classifying liver iron concentration in thalassemic patients is presented. In this work, an ANN is used to validate the output of the L.I.O.MO.T (Liver Iron Overload Monitoring in Thalassemia) method against the output of the state-of-the-art method based on MRI T2 assessment for liver iron concentration. The model has been validated with a dataset of 200 samples. The experimental Mean Squared Error results and Correlation show interesting performances. The proposed algorithm has been developed as a plug in for OsiriX Dicom View…

Settore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniLiver Iron ConcentrationMean squared errorArtificial neural networkComputer scienceRemote patient monitoringbusiness.industryComputational intelligenceComplex problem solvingcomputer.software_genreExpert systemLIOMOT MRI T2* Iron Liver Thalassemia Artificial Neural Network Expert System OsiriXLiver ironArtificial intelligenceData miningbusinesscomputer
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Different patterns of myocardial iron distribution by whole-heart T2* magnetic resonance as risk markers for heart complications in thalassemia major.

2014

Background The multislice multiecho T2* cardiovascular magnetic resonance (CMR) technique allows to detect different patterns of myocardial iron overload (MIO). The aim of this cross-sectional study was to verify the association between cardiac complications (heart failure and arrhythmias), biventricular dysfunction and myocardial fibrosis with different patterns of MIO in thalassemia major (TM) patients. Methods We considered 812 TM patients enrolled in the Myocardial Iron Overload in Thalassemia (MIOT) Network. The T2* value in all the 16 cardiac segments was evaluated. Results We identified 4 groups of patients: 138 with homogeneous MIO (all segments with T2* < 20 ms), 97 with heterogene…

AdultMalemedicine.medical_specialtyHeart DiseasesThalassemiaIronMyocardial ironMagnetic Resonance Imaging CineMyocardial iron overloadYoung AdultRisk FactorsInternal medicineMedicineDistribution (pharmacology)HumansMultisliceChelation therapyCardiac complicationThalassemia majormedicine.diagnostic_testbusiness.industryMyocardiumbeta-ThalassemiaMagnetic resonance imagingmedicine.diseaseCross-Sectional StudiesHeart failureCardiologyMyocardial fibrosisCardiovascular magnetic resonanceFemaleCardiology and Cardiovascular MedicinebusinessInternational journal of cardiology
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Influence of image reconstruction parameters on cardiovascular risk reclassification by Computed Tomography Coronary Artery Calcium Score

2018

Objective: To investigate the influence of different CT reconstruction parameters on coronary artery calcium scoring (CACS) values and reclassification of predicted cardiovascular (CV) risk. Methods: CACS was evaluated in 113 patients undergoing ECG-gated 64-slice CT. Reference CACS protocol included standard kernel filter (B35f) with slice thickness/increment of 3/1.5 mm, and field-of-view (FOV) of 150–180 mm. Influence of different image reconstruction algorithms (reconstructed slice thickness/increment 2.0/1.0–1.5/0.8–3.0/2.0–3.0/3.0 mm; slice kernel B30f-B45f; FOV 200–250 mm) on Agatston score was assessed by Bland-Altman plots and concordance correlation coefficient (CCC) ana…

MaleAccuracy and precisionRadiology Nuclear Medicine and ImagingCardiac computed tomographyComputed Tomography AngiographyComputed tomographyIterative reconstructionCoronary Artery Disease030204 cardiovascular system & hematologyRisk Assessment030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineImage reconstruction algorithmRisk FactorsImage Processing Computer-AssistedMedicineHumansReconstruction parameterProspective StudiesVascular CalcificationAgedReconstruction parametersmedicine.diagnostic_testCoronary artery calcium scorebusiness.industryCoronary artery calcium scoreCardiovascular risk classificationGeneral MedicineMiddle AgedCardiovascular riskConcordance correlation coefficientCardiovascular DiseasesCardiac computed tomography; Cardiovascular risk; Cardiovascular risk classification; Coronary artery calcium score; Reconstruction parametersFemalebusinessAgatston scoreNuclear medicineSettore MED/36 - Diagnostica Per Immagini E RadioterapiaCoronary Artery Calcium ScoringAlgorithms
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Aortic valve and vascular calcium score in pre-TAVI CT: correlation with early post-procedural complications

2023

Abstract Purpose The aim of our study was to evaluate the prevalence of early complications after Transcatheter Aortic Valve Implantation (TAVI) and their correlation with the Calcium Score (CS) of the aortic valve, aorta and ilio-femoral arteries derived from pre-procedural computed tomography (CT). Materials and methods We retrospectively reviewed 226 patients (100 males, mean age 79.4 ± 6.7 years) undergoing 64-slice CT for pre-TAVI evaluation from January 2018 to April 2021. The population was divided into CS quartiles. Results Overall, 173 patients underwent TAVI procedure, of whom 61% presented paravalvular leak after the procedure, 28% presented bleeding or vascular complications, 25…

Transcatheter aortic valve implantation.Radiology Nuclear Medicine and imagingGeneral MedicineComputed tomography angiographySettore MED/36 - Diagnostica Per Immagini E RadioterapiaComplicationCalcium score
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Quantification of epicardial fat with cardiac CT angiography and association with cardiovascular risk factors in symptomatic patients: From the ALTER…

2019

PURPOSE We aimed to assess the association between features of epicardial adipose tissue and demographic, morphometric and clinical data, in a large population of symptomatic patients with clinical indication to cardiac computed tomography (CT) angiography. METHODS Epicardial fat volume (EFV) and adipose CT density of 1379 patients undergoing cardiac CT angiography (918 men, 66.6%; age range, 18–93 years; median age, 64 years) were semi-automatically quantified. Clinical variables were compared between diabetic and nondiabetic patients to assess potential differences in EFV and adipose CT density. Multiple regression models were calculated to find the clinical variables with a significant a…

AdultMalemedicine.medical_specialtyRadiology Nuclear Medicine and ImagingComputed Tomography AngiographyHypercholesterolemiaAdipose tissue030218 nuclear medicine & medical imagingBody Mass Index03 medical and health sciences0302 clinical medicineRisk FactorsRetrospective StudieInternal medicineDiabetes mellitusCardiovascular DiseaseDiabetes MellitusmedicineHumansPericardiumCardiovascular ImagingRetrospective StudiesComputed tomography angiographyAgedAged 80 and overmedicine.diagnostic_testbusiness.industryRisk FactorRetrospective cohort studyDiabetes MellituBiomarkerMiddle Agedmedicine.diseaseEpicardial fatmedicine.anatomical_structureAdipose TissueCardiovascular DiseasesAngiographyHypertensionCardiologyFemalebusinessCardiology and Cardiovascular MedicineBody mass indexPericardiumBiomarkersHuman
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Quantification of epicardial adipose tissue in coronary calcium score and CT coronary angiography image data sets: comparison of attenuation values, …

2016

The aim of the study was to compare epicardial adipose tissue (EAT) characteristics assessed with coronary calcium score (CS) and CT coronary angiography (CTCA) image data sets.In 76 patients (mean age 59 ± 13 years) who underwent CS and CTCA owing to suspected coronary artery disease (CAD), EAT was quantified in terms of density (Hounsfield units), thickness and volume. The EAT volume was extracted with a semi-automatic software.A moderate correlation was found between EAT density in CS and CTCA image data sets (-100 ± 19 HU vs -70 ± 24 HU; p  0.05, r = 0.55). The distribution of EAT was not symmetrical with a maximal thickness at the right atrioventricular groove (14.2 ± 5.3 mm in CS, 15.…

MaleCoronary angiographyComputed Tomography AngiographyAdipose tissueCoronary Artery Disease030204 cardiovascular system & hematologyCoronary AngiographySensitivity and Specificity030218 nuclear medicine & medical imagingCoronary artery disease03 medical and health sciencesImaging Three-Dimensional0302 clinical medicineHounsfield scalemedicineHumansRadiology Nuclear Medicine and imagingVascular CalcificationAdiposityComputed tomography angiographyFull Papermedicine.diagnostic_testbusiness.industryReproducibility of ResultsMean ageGeneral MedicineMiddle Agedmedicine.diseaseCoronary Calcium ScoreAdipose Tissueepicardial adipose tissue CT coronary angiographyEpicardial adipose tissueRadiographic Image Interpretation Computer-AssistedFemaleSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessNuclear medicinePericardiumAlgorithmsThe British Journal of Radiology
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Integrated non-invasive approach to atherosclerosis with cardiac CT and carotid ultrasound in patients with suspected coronary artery disease

2017

The aim of the study was to compare the atherosclerotic disease in the coronary and carotid arteries in patients who underwent non-invasive imaging for suspected stable coronary artery disease (CAD). 107 patients (64 men, age 59 ± 12) with atypical chest pain underwent cardiac CT (CCT) and carotid ultrasound (US) on the same day. Severity (obstructive or not-obstructive disease), location, shape, and composition of atherosclerotic plaques in the two districts were evaluated. Patients presented normal coronary arteries in 36 % (n = 38), not-obstructive CAD in 36 % (n = 39), and obstructive CAD in 28 % (n = 30), while had normal carotid arteries in 53 % (n = 57), not-obstructive disease in 44…

Carotid ultrasoundMalemedicine.medical_specialtyCarotid arteriesCardiac-Gated Imaging TechniquesContrast Media030204 cardiovascular system & hematologyCoronary AngiographySeverity of Illness IndexCoronary artery diseaseDoppler ultrasound030218 nuclear medicine & medical imagingLesionCoronary artery disease03 medical and health sciences0302 clinical medicineInternal medicineImage Interpretation Computer-AssistedmedicineCardiac CTHumansRadiology Nuclear Medicine and imagingIn patientCarotid StenosisNeuroradiologyUltrasonographymedicine.diagnostic_testbusiness.industryUltrasoundInterventional radiologyCarotid arterieGeneral MedicineMiddle Agedmedicine.diseaseAtherosclerosisIopamidolAtherosclerosiCardiologyFemaleRadiologymedicine.symptombusinessTomography X-Ray ComputedSettore MED/36 - Diagnostica Per Immagini E RadioterapiaRadiologia Medica
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Response Assessment to Cancer Therapy

2021

Cancer generically refers to a group of diseases showing an uncontrolled division of abnormal cells potentially having the ability to invade, through the blood and lymph systems, nearby tissues or spread to other parts of the body.

OncologyResponse assessmentmedicine.medical_specialtybusiness.industryInternal medicinemedicineCancer therapyCancerAbnormal cellLymphmedicine.diseasebusiness
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Choline PET/CT Features to Predict Survival Outcome in High Risk Prostate Cancer Restaging: A Preliminary Machine-Learning Radiomics Study

2020

Background Radiomic features are increasingly utilized to evaluate tumor heterogeneity in PET imaging but to date its role has not been investigated for Cho-PET in prostate cancer. The potential application of radiomics features analysis using a machine-learning radiomics algorithm was evaluated to select 18F-Cho PET/CT imaging features to predict disease progression in PCa. Methods We retrospectively analyzed high-risk PCa patients who underwent restaging 18F-Cho PET/CT from November 2013 to May 2018. 18F-Cho PET/CT studies and related structures containing volumetric segmentations were imported in the "CGITA" toolbox to extract imaging features from each lesion. A Machine-learning model h…

Malemedicine.medical_specialtyn artificial intelligence model demonstrated to be feasible and able to select a panel of 18F-Cho PET/CT features with valuable association with PCa patients' outcome.business.industryProstatic NeoplasmsFeature selectionPet imagingCholine pet ctmedicine.diseaseTumor heterogeneitySurvival outcomeCholineMachine LearningProstate cancerRadiomicsFeature (computer vision)Artificial IntelligencePositron Emission Tomography Computed TomographyMedicineHumansRadiology Nuclear Medicine and imagingRadiologybusinessRetrospective Studies
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Post-operative computed tomography imaging evaluation of ascending aorta surgery

2021

Ascending thoracic aorta disease is often a life-threatening condition. Aortic aneurysm and aortic dissection are the most frequent ascending aorta diseases requiring surgical intervention. Surgical repair techniques of the ascending aorta are various; they include reconstruction of the ascending aorta by using a graft with or without a prosthetic valve, reconstruction with a composite artificial graft or using a biological graft, and reconstruction of the ascending aorta with a composite graft preserving the native valve and arch repair. The radiologist plays a key role in the identification of post-operative complications; differentiation from normal postoperative findings is fundamental.…

ascending aorta-surgerymedicine.medical_specialtypost-operative complicationsComputed tomographyelephant-trunk procedureArtificial graftAortic aneurysmmedicine.arteryAscending aortapost-operative CT imagingMedicineThoracic aortaPost operativeBentall-De Bono procedureBentall-De BonprocedureAortic dissectionSurgical repairReview Papermedicine.diagnostic_testbusiness.industrymedicine.diseaseSurgerygraftcardiovascular systemSettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness
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Imaging the COVID-19: a practical guide

2021

The Coronavirus Disease 2019 (COVID-19) represents the first medical catastrophe of the new millennium. Although imaging is not a screening test for COVID-19, it plays a crucial role in evaluation and follow-up of COVID-19 patients. In this paper, we will review typical and atypical imaging findings of COVID-19.

Pulmonary and Respiratory Medicine2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Screening testbusiness.industrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)lcsh:RCOVID-19lcsh:MedicineVirology030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineMedicineCOVID-19 pneumoniaCardiology and Cardiovascular Medicinebusiness030217 neurology & neurosurgeryCTCOVID-19; CT; COVID-19 pneumonia.
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Outcome of LR-3 and LR-4 observations without arterial phase hyperenhancement at Gd-EOB-DTPA-enhanced MRI follow-up

2020

Objective: The aim of this study was to retrospectively analyze the outcome of LR-3 and LR-4 without arterial phase hyperenhancement (APHE), and identify which features could predict LR-5 progression on serial Gd-EOB-DTPA-enhanced MRI follow-up. Methods: Forty-nine cirrhotic patients with 55 LR-3 and 19 LR-4 without APHE were evaluated. Observations were classified as decreased, stable or increased in category at follow-up. Observation size and LI-RADS major and ancillary features were evaluated. Results: Seventeen/fifty-five (31%) LR-3 and 8/19 (42%) LR-4 progressed to LR-5 at follow-up. Baseline LI-RADS major and ancillary features were not significantly different among LR-3 and LR-4. A d…

Gadolinium DTPAGd-EOB-DTPA-enhanced MRILR-3Carcinoma HepatocellularLR-4business.industryLiver NeoplasmsGd-EOB-DTPAContrast MediaMagnetic Resonance Imaging030218 nuclear medicine & medical imagingSettore MED/01 - Statistica Medica03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisMedicineHumansLI-RADSRadiology Nuclear Medicine and imagingNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaArterial phaseFollow-Up StudiesRetrospective Studies
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Myocardial blood flow quantification for evaluation of coronary artery disease by computed tomography

2017

During the last decade coronary computed tomography angiography (CTA) has become the preeminent non-invasive imaging modality to detect coronary artery disease (CAD) with high accuracy. However, CTA has a limited value in assessing the hemodynamic significance of a given stenosis due to a modest specificity and positive predictive value. In recent years, different CT techniques for detecting myocardial ischemia have emerged, such as CT-derived fractional flow reserve (FFR-CT), transluminal attenuation gradient (TAG), and myocardial CT perfusion (CTP) imaging. Myocardial CTP imaging can be performed with a single static scan during first pass of the contrast agent, with monoenergetic or dual…

medicine.medical_specialtyCardiac computed tomographyMyocardial blood flow quantificationPerfusion scanningFractional flow reserveReview Article030204 cardiovascular system & hematology030218 nuclear medicine & medical imagingCoronary artery disease03 medical and health sciencesMyocardial perfusion imaging0302 clinical medicineStress imagingInternal medicinemedicinemedicine.diagnostic_testbusiness.industryMyocardial perfusion imagingmedicine.diseaseRegadenosonDipyridamoleCoronary artery disease (CAD)StenosisCardiologyRadiologyCoronary vasodilatorbusinessCardiology and Cardiovascular MedicineSettore MED/36 - Diagnostica Per Immagini E Radioterapiamedicine.drug
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Assessment of atrial diastolic function in patients with hypertrophic cardiomyopathy by cine magnetic resonance imaging

2015

Purpose: This study was conducted to assess the role of atrial function by cardiac magnetic resonance (CMR) for the evaluation of diastolic physiology in patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls. Materials and methods: We enrolled 23 consecutive patients affected by HCM and 43 healthy subjects as age-matched control cases (CC). CMR was performed through acquisition of cine steady-state free precession sequences using a 1.5-T scanner. Image postprocessing was carried out using Tracking Tool software. Results: Atrial volumes were significantly higher in patients with HCM compared to CC: maximum atrial volume (p = 0.007) and minimum atrial volume (p = 0.01).…

AdultMalemedicine.medical_specialtyRadiology Nuclear Medicine and ImagingDiastolic functionCardiac magnetic resonanceDiastoleContrast MediaMagnetic Resonance Imaging CineDiastoleInternal medicineImage Interpretation Computer-AssistedmedicineOrganometallic CompoundsHumansIn patientDiastolic functioncardiovascular diseasesHeart AtriaNeuroradiologyOrganometallic Compoundmedicine.diagnostic_testbusiness.industryMedicine (all)UltrasoundAtrial functionHypertrophic cardiomyopathyMagnetic resonance imagingInterventional radiologyGeneral MedicineCardiomyopathy Hypertrophicmedicine.diseaseHypertrophic cardiomyopathyCase-Control Studiescardiovascular systemCardiologyFemalebusinessCase-Control StudieSettore MED/36 - Diagnostica Per Immagini E RadioterapiaHuman
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Intravenous Contrast Material for Cardiac Computed Tomography

2023

Purpose: The Italian Registry of Contrast Material use in Cardiac Computed Tomography (iRCM-CCT) is a multicenter, multivendor, observational study on the use of contrast media (CM) in patients undergoing cardiac computed tomography (CCT). The aim of iRCM-CCT is to assess image quality and safety profile of intravenous CM compounds. Materials and methods: iRCM-CCT enrolled 1842 consecutive patients undergoing CCT (≥50 per site) at 20 cluster sites with the indication of suspected coronary artery disease. Demographic characteristics, CCT, and CM protocols, clinical indications, safety markers, radiation dose reports, qualitative (ie, poor vascular enhancement) and quantitative (ie, HU attenu…

safetyPulmonary and Respiratory MedicineSettore MED/36 - Diagnostica per Immagini e Radioterapiacoronary arteriecomputed tomography angiography; contrast media; coronary arteries; image enhancement; safetyRadiology Nuclear Medicine and imagingcomputed tomography angiography; contrast media; coronary arteries; image enhancement; safety;image enhancementcontrast mediacomputed tomography angiographycoronary arteriesimage enhancement contrast media safetycomputed tomography angiographycoronary arteriesimage enhancementcontrast mediasafetyJournal of Thoracic Imaging
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Preoperative imaging findings in patients undergoing transcranial magnetic resonance imaging-guided focused ultrasound thalamotomy

2021

AbstractThe prevalence and impact of imaging findings detected during screening procedures in patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy for functional neurological disorders has not been assessed yet. This study included 90 patients who fully completed clinical and neuroradiological screenings for tcMRgFUS in a single-center. The presence and location of preoperative imaging findings that could impact the treatment were recorded and classified in three different groups according to their relevance for the eligibility and treatment planning. Furthermore, tcMRgFUS treatments were reviewed to evaluate the number of transducer elements turned off after…

Maletranscranial magnetic resonance; thalamotomy; neurological disordersParkinson's diseasemedicine.medical_treatmentneurological disordersNeuropathic paintranscranial magnetic resonance030218 nuclear medicine & medical imaging0302 clinical medicineThalamusMass ScreeningRadiation treatment planningScreening proceduresAged 80 and overeducation.field_of_studyMultidisciplinarymedicine.diagnostic_testSettore MED/27 - NeurochirurgiaQRSettore MED/37 - NeuroradiologiaDisease ManagementMiddle AgedMagnetic Resonance ImagingSurgery Computer-AssistedMedicineStereotaxic TechniqueSettore MED/26 - NeurologiaFemaleRadiologyAdultmedicine.medical_specialtyEssential TremorScienceClinical Decision-MakingPopulationNeuroimagingArticleFocused ultrasoundMultiple sclerosisYoung Adult03 medical and health sciencesComputed TomographyMedical researchParkinson’s Disease.Preoperative CaremedicineHumansInterventional Magnetic Resonance ImagingIn patientMovement disorderseducationHigh-intensity Focused Ultrasound AblationUltrasonography InterventionalAgedThalamotomybusiness.industryMagnetic resonance imagingthalamotomySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Diseases of the nervous systemSettore MED/36 - Diagnostica Per Immagini E RadioterapiaTomography X-Ray ComputedbusinessMR-guided Focused Ultrasound030217 neurology & neurosurgeryNeurosciencePreoperative imaging
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Non Invasive Imaging of Myocardial Infarction with Computed Tomography and Magnetic Resonance

2012

Myocardial infarction is a major cause of death and disability worldwide. Myocardial infarction may represent a major catastrophic event leading to severe hemodynamic failure or sudden death or it may occur repeatedly in patients with established heart disease. In this context, the role of imaging techniques may become useful for the understanding of the determinants in a preclinical setting before acute coronary events, and for an accurate and correct diagnosis of myocardial infarction. Three-dimensional noninvasive imaging techniques, such as Cardiac CT (CCT) and Cardiac MR imaging (CMR) were widely developed in the last two decades. These imaging techniques may provide new insights into …

medicine.medical_specialtyHeart diseaseContext (language use)Coronary Artery DiseaseSudden deathInternal medicineMedicineHumanscardiovascular diseasesMyocardial infarctionPharmacologymedicine.diagnostic_testbusiness.industryCoronary StenosisElectrocardiography in myocardial infarctionMagnetic resonance imagingmedicine.diseaseCoronary arteriesMyocardial infarctionmedicine.anatomical_structurecardiovascular systemCardiologyRadiologyMyocardial infarction diagnosisCardiology and Cardiovascular MedicinebusinessMagnetic Resonance AngiographyTomography Emission-Computed
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Role of cardiac computed tomography in the evaluation of coronary artery stenosis in patients with ascending aorta aneurysm detected at transthoracic…

2016

OBJECTIVE The aim of our study was to evaluate the diagnostic performance of cardiac computed tomography (CCT) in the evaluation of coronary artery stenosis in patients with ascending aorta aneurysm detected at transthoracic echocardiography. METHODS We conducted a retrospective analysis of patients with an aneurysm 45 mm or greater at transthoracic echocardiography who underwent CCT from 2012 to 2014 in our hospital. We calculated the sensitivity, specificity, and positive and negative predictive values of CCT for the assessment of coronary artery stenosis (<50% or ≥50% stenosis) in patients who underwent conventional coronary angiography. RESULTS We included 104 patients (73 men, aged 64 …

Malemedicine.medical_specialtyRadiology Nuclear Medicine and ImagingTransthoracic echocardiography030204 cardiovascular system & hematologyCoronary AngiographyMultimodal ImagingSensitivity and Specificity030218 nuclear medicine & medical imagingCoronary artery disease03 medical and health sciencesAortic aneurysm0302 clinical medicineAneurysmmedicine.arteryPositive predicative valueInternal medicineAscending aortamedicineCardiac CTHumansAortaAortabusiness.industryCoronary StenosisReproducibility of ResultsMiddle Agedmedicine.diseaseAneurysmAortic AneurysmStenosismedicine.anatomical_structureEchocardiographyCardiologyFemaleRadiologyTomography X-Ray ComputedbusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaArtery
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Technical development in cardiac CT: current standards and future improvements—a narrative review

2020

Non-invasive depiction of coronary arteries has been a great challenge for imaging specialists since the introduction of computed tomography (CT). Technological development together with improvements in spatial, temporal, and contrast resolution, progressively allowed implementation of the current clinical role of the CT assessment of coronary arteries. Several technological evolutions including hardware and software solutions of CT scanners have been developed to improve spatial and temporal resolution. The main challenges of cardiac computed tomography (CCT) are currently plaque characterization, functional assessment of stenosis and radiation dose reduction. In this review, we will discu…

medicine.medical_specialtyCardiac computed tomographyPrognosiComputed tomography030204 cardiovascular system & hematology030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicineMedical physicsmedicine.diagnostic_testbusiness.industryContrast resolutionRadiation doseCoronary artery disease (CAD)Coronary arteriesmedicine.anatomical_structureAtherosclerosiCt scannersNarrative reviewTherapyReview Article on Impact of Cardiac CT in Clinical PracticeCardiology and Cardiovascular MedicinebusinessCardiac computed tomography (CCT)DiagnosiCardiovascular Diagnosis and Therapy
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The spectrum of risk factors for contrast induced nephropathy in patients undergoing coronary angiography or intervention

2014

Abstract Introduction Contrast induced nephropathy is an unfavorable acute event which can complicate the clinical course of patients undergoing coronary angiography. Clinical characteristics predisposing to its occurrence are still rather obscure. Methods We enrolled 591 patients (mean age 64.2 ± 10.98; 449 male and 142 female) who underwent emergency or elective Coronary angiography/Angioplastic in our Cardiologic Division between 10/2006 and 06/2008, paying attention to their Cardiovascular risk factors, dose and type of contrast medium, type and number of affected coronary arteries, pharmacological therapies, baseline renal function and extracoronary atherosclerosis. We performed a univ…

medicine.medical_specialtyCreatininebusiness.industryContrast-induced nephropathyRenal functionFibrinogenmedicine.diseaseCoronary arteriessymbols.namesakeContrast mediumchemistry.chemical_compoundmedicine.anatomical_structurechemistryInternal medicineDiabetes mellitusmedicineCardiologysymbolsbusinessFisher's exact testmedicine.drugJournal of Indian College of Cardiology
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Clinical relevance of myocardial bridging detected by coronary CT angiography in patients with atypical chest pain

2019

MaleChest Painmedicine.medical_specialtycoronary CT angiography atypical chest painMyocardial bridgingComputed Tomography AngiographyMyocardial BridgingCoronary Angiographycoronary CT angiographyHumansMedicineClinical significanceIn patientCoronary VesselAgedbusiness.industryAngiographyAtypical chest painCoronary ct angiographyatypical chest painMiddle AgedCoronary VesselsFemaleRadiologyTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessHumanMinerva Cardioangiologica
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Working in the mirror: The safety and effectiveness of closure access leading venous advanced gain new ability in a patient with dextrocardia

2018

The evolution of devices in serious cardiac rhythm pathology management and in other medicine areas and its optimal management have progressively become a worldwide serious challenge. We present an upgrading to dual chamber im-plantable cardioverter-defibrillator (ICD) without complications in a 68 year old woman through closure access leading venous advanced gain new ability, complementing the mechanical multiple venous entry-site approach extraction. This is another of the few cases present in literature about ICD in patients with dextrocardia and it focuses on the safety and effectiveness of our simple technique also in a patient with dextrocardia.

DeflibrillatorGeneral MedicineDextrocardiaCardiacArrhythmia
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Infarct characterization using CT

2017

Myocardial infarction (MI) is a major cause of death and disability worldwide. The incidence is not expected to diminish, despite better prevention, diagnosis and treatment, because of the ageing population in industrialized countries and unhealthy lifestyles in developing countries. Nowadays it is highly requested an imaging tool able to evaluate MI and viability. Technology improvements determined an expansion of clinical indications from coronary plaque evaluation to functional applications (perfusion, ischemia and viability after MI) integrating additional phases and information in the mainstream examination. Cardiac computed tomography (CCT) and cardiac MR (CMR) employ different contra…

medicine.medical_specialtycoronary arterieIschemiaReview Article030204 cardiovascular system & hematologyPharmacological stress030218 nuclear medicine & medical imagingIodinated contrast media03 medical and health sciences0302 clinical medicineImaging Toolcardiovascular diseasemedicineMyocardial infarctionmyocardial infarction (MI)Cause of deathbusiness.industrycomputed tomographymedicine.diseaseCoronary arteriesmedicine.anatomical_structureAtherosclerosiRadiologyCardiology and Cardiovascular MedicinebusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaPerfusionCardiovascular Diagnosis and Therapy
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Imaging features of adrenal masses

2019

Abstract The widespread use of imaging examinations has increased the detection of incidental adrenal lesions, which are mostly benign and non-functioning adenomas. The differentiation of a benign from a malignant adrenal mass can be crucial especially in oncology patients since it would greatly affect treatment and prognosis. In this setting, imaging plays a key role in the detection and characterization of adrenal lesions, with several imaging tools which can be employed by radiologists. A thorough knowledge of the imaging features of adrenal masses is essential to better characterize these lesions, avoiding a misinterpretation of imaging findings, which frequently overlap between benign …

Adenomalcsh:Medical physics. Medical radiology. Nuclear medicinemedicine.medical_specialtyAdenomalcsh:R895-920ReviewImaging modalitiesAdrenal massesMagnetic resonance imagingMedicineRadiology Nuclear Medicine and imagingAdrenal imagingAdrenalComputed tomographyNeuroradiologymedicine.diagnostic_testbusiness.industryMagnetic resonance imagingInterventional radiologymedicine.diseaseSettore MED/18 - Chirurgia GeneraleOncology patientsRadiologySettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessChemical shift imagingInsights into Imaging
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MR-guided focused ultrasound application for moving target tumor ablation in abdominal area: Coil selection

2020

PubMed: 32276552

SwineThermal ablationMagnetic Resonance Imaging InterventionalTumor ablationFocused ultrasound030218 nuclear medicine & medical imagingMagnetic resonance guided focused ultrasound surgery03 medical and health sciencesCE marking0302 clinical medicineEcho planar imagingAbdomenAnimalsHumansMedicineRadiology Nuclear Medicine and imagingRadiological and Ultrasound TechnologyEcho-Planar ImagingPhantoms Imagingbusiness.industryCoils magnetic resonance thermometry tracking echo planar imaging magnetic resonance-guided focused-ultrasound surgery CE marking validation verificationTrackingLiver NeoplasmsVerificationSettore MED/37 - NeuroradiologiaCoilsGeneral MedicineFocused ultrasound surgeryDisease Models AnimalLiverMagnetic resonance thermometryElectromagnetic coil030220 oncology & carcinogenesisHigh-Intensity Focused Ultrasound AblationbusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaMri guidedMagnetic resonance thermometryBiomedical engineering
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Transcranial Magnetic Resonance Imaging-Guided Focused Ultrasound with a 1.5 Tesla Scanner: A Prospective Intraindividual Comparison Study of Intraop…

2021

Background: High-quality intraoperative imaging is needed for optimal monitoring of patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy. In this paper, we compare the intraoperative imaging obtained with dedicated FUS-Head coil and standard body radiofrequency coil in tcMRgFUS thalamotomy using 1.5-T MR scanner. Methods: This prospective study included adult patients undergoing tcMRgFUS for treatment of essential tremor. Intraoperative T2-weighted FRFSE sequences were acquired after the last high-energy sonication using a dedicated two-channel FUS-Head (2ch-FUS) coil and body radiofrequency (body-RF) coil. Postoperative follow-ups were performed at 48 h usin…

Scannerhigh-intensity focused ultrasound ablationmedicine.medical_treatmentArticleFocused ultrasoundlcsh:RC321-571030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineMcNemar's testmedicinemagnetic resonance imagingimage qualityessential tremorlcsh:Neurosciences. Biological psychiatry. Neuropsychiatrymedicine.diagnostic_testSettore MED/27 - Neurochirurgiabusiness.industryThalamotomyGeneral NeuroscienceMR-guided focused ultrasoundSettore MED/37 - NeuroradiologiaMagnetic resonance imagingstereotaxic techniquesElectromagnetic coilStereotaxic techniquefocused ultrasoundSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessNuclear medicine030217 neurology & neurosurgeryRadiofrequency coilBrain Sciences
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Role of computed tomography and magnetic resonance imaging in local complications of acute pancreatitis

2019

Acute pancreatitis (AP) represents a pancreas inflammation of sudden onset that can present different degrees of severity. AP is a frequent cause of acute abdomen and its complications are still a cause of death. Biliary calculosis and alcohol abuse are the most frequent cause of AP. Computed tomography (CT) and magnetic resonance imaging (MRI) are not necessary for the diagnosis of AP but they are fundamental tools for the identification of the cause, degree severity and AP complications. AP severity assessment is in fact one of the most important issue in disease management. Contrast-enhanced CT is preferred in the emergency setting and is considered the gold standard in patients with AP.…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryComputed tomographyMagnetic resonance imagingGold standard (test)Review Articlemedicine.diseaseAcute pancreatitis (AP)SepsisVenous thrombosisAcute abdomenmedicineAcute pancreatitisSurgeryRadiologyMagnetic resonance imaging (MRI)medicine.symptombusinessAcute pancreatitis (AP) Computed tomography (CT) Magnetic resonance imaging (MRI)Settore MED/36 - Diagnostica Per Immagini E RadioterapiaComputed tomography (CT)Cause of death
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Updated diagnosticprognostic paradigm for CAD: a narrative review.

2020

Cardiovascular diseases are the first cause of death globally; early detection of coronary artery disease (CAD) is a challenge for clinicians and radiologists. Over the past 2 decades there have been several improvements in the methods for the assessment of diagnosis and prognosis in patients with suspected CAD; most of these methods are imaging methods and they operate with high-end technologies. Cardiac computed tomography (CCT) as we know it today was introduced in 1998 and has ever progressed with constant pace. The first decade was the technical validation phase of the method while the second decade was the clinical validation phase. CCT has developed an excellent diagnostic and progno…

medicine.medical_specialtyPharmacological therapyPrognosiEarly detectionCAD010501 environmental sciences01 natural sciencesCoronary artery disease03 medical and health sciences0302 clinical medicineOptimal medical therapy (OMT)MedicineIn patient030212 general & internal medicineIntensive care medicine0105 earth and related environmental sciencesCause of deathbusiness.industryTherapy.medicine.diseaseCoronary artery disease (CAD)AtherosclerosiCohortNarrative reviewReview Article on Impact of Cardiac CT in Clinical PracticeCardiology and Cardiovascular MedicinebusinessCardiac computed tomography (CCT)DiagnosiCardiovascular diagnosis and therapy
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Prognostic value of cardiac CT

2020

In the past decades, coronary computed tomography angiography (CCTA) has become a powerful tool in the management of coronary artery disease. The diagnostic and prognostic value of CCTA has been extensively demonstrated in both large observational studies and clinical trials among stable chest pain patients. The quantification of coronary artery calcium score (CACS) is a well-established predictor of cardiovascular morbidity and mortality in asymptomatic subjects. Besides CACS, the main strength of CCTA is the accurate assessment of the individual total atherosclerotic plaque burden, which holds important prognostic information. In addition, CCTA, by providing detailed information on corona…

medicine.medical_specialtyPrognosiComputed Tomography Angiographymedicine.medical_treatmentPerfusion scanningFractional flow reserveCoronary Artery DiseaseCoronary AngiographyRevascularizationChest painAsymptomatic030218 nuclear medicine & medical imagingCoronary computed tomographyCoronary artery diseaseChest pain03 medical and health sciences0302 clinical medicineInternal medicinemedicineCardiac CTHumansRadiology Nuclear Medicine and imagingCADVascular CalcificationNeuroradiologyFFR-CTRisk assessmentRandomized Controlled Trials as TopicVascular Calcification.Asymptomatic Diseasemedicine.diagnostic_testbusiness.industryCACSInterventional radiologyHeartGeneral MedicinePrognosismedicine.diseaseCardiovascular imaging030220 oncology & carcinogenesisAtherosclerosiAsymptomatic DiseasesCardiologyRisk factormedicine.symptomStratificationbusiness
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TAVI imaging: over the echocardiography

2020

Aortic valve stenosis (AS) is a common valvular heart disease. Recently, transcatheter aortic valve implantation (TAVI) has changed the treatment of severe AS in elderly patients with contraindications to traditional surgical replacement. Echocardiography is conventionally used as the first imaging modality to assess the presence and severity of AS and to provide anatomical and functional information. Nowadays, imaging techniques play a crucial role in the planning of TAVI to define suitable candidates. Computed tomography (CT) is essential to display the anatomy of the aortic valve complex (including aortic annulus, Valsalva sinuses, coronary arteries ostia, sinotubular junction), thoracoa…

Aortic valvemedicine.medical_specialtyAortic valve stenosisCoronary Angiography030218 nuclear medicine & medical imagingTranscatheter Aortic Valve Replacement03 medical and health sciences0302 clinical medicineMagnetic resonance imagingmedicineHumansRadiology Nuclear Medicine and imagingCardiac skeletonComputed tomographyNeuroradiologyAgedIncidental FindingsTranscatheter aortic valve implantationmedicine.diagnostic_testbusiness.industryvalvular heart diseaseSettore ING-IND/34 - Bioingegneria IndustrialeMagnetic resonance imagingInterventional radiologyGeneral Medicinemedicine.diseaseCoronary arteriesmedicine.anatomical_structureEchocardiography030220 oncology & carcinogenesisAortic valve stenosiscardiovascular systemRadiologybusinessTomography X-Ray ComputedSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Imaging dell'amiloidosi cardiaca in Risonanza Magnetica: Case Report.

2016

Amyloidosis is a rare group of diseases characterized by the deposition of amyloid protein level of various tissues and organs, including myocardial tissue, with progressive evolution towards heart failure. We report the case of a 76-year-old male patient with dyspnoea and easy fatigue, whose picture of Magnetic resonance imaging enabled the diagnosis of cardiac amyloidosis.

Settore MED/36 - Diagnostica Per Immagini E Radioterapiaamiloidosi cardiaca risonanza magnetica
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Coartazione aortica in tomografia computerizzata multistrato

2016

Aortic coarctation (CA) is a congenital focal narrowing of the aortic lumen forming part of an arteriopathy generalized (5-8% of all congenital heart diseases). Classically distinct in a predeterminal and postductal form, at present this classification is not used much. Clinical manifestations of affected patients range from systolic hypertension of the originating vessels a upstream of the part coarctated to the hypotension dependent on those downstream and strictly depend on the degree of stenosis.

coartazione aortica tc multistrato
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Assessment of volume and density of epicardial fat: comparison between CT calcium score and CT coronary angiography scans.

2015

Aims and objectives Methods and materials Results Conclusion Personal information References

Computer Applications-Generalgenetic structuresArteriosclerosisSettore MED/36 - Diagnostica Per Immagini E RadioterapiaCardiacCT-Angiographyepicardial fat CT calcium score CT coronary angiography
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Risonanza Magnetica (RM) renale per la valutazione quantitativa del sovraccarico di ferro con sequenze T2*: valori normali per età e sesso.

2016

The objective of this study is to examine the reliability and reproducibility of multi-echo gadient-echo (ME-GRE) T2 sequences for the measurement of global and regional renal T2 values, establish normal cut-offs in healthy patients and evaluate the correlation of values ​​obtained with age and sex.

Risonanza Magnetica renale ferroSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Gestione della dose in Cardio-TC

2016

Exposure to ionizing radiation for diagnostic investigations has aroused much concern in recent years both in scientific literature and in the media. The exposure has dramatically increased in the last two decades; in fact, CT represents 11% of diagnostic tests, but contributes 68% to the collective dose. On the other singing, a plethora of TC investigations, including screening of the thorax in smokers, virtual colonoscopy and the study of coronary, they are affirmed for the relative simplicity of execution and high diagnostic performance, sometimes alternatively to traditional and more expensive invasive techniques. Between these investigations, the Cardio TC (CTC) has achieved a remarkab…

Settore MED/36 - Diagnostica Per Immagini E Radioterapiadose radiazioni ionizzanti tc
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ANOMALIE DI MOVIMENTO DEL VENTRICOLO SINISTRO NEI PAZIENTI CON TALASSEMIA MAJOR

2014

TALASSEMIA MAJOR
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La TC coronarica nel paziente stabile: approccio clinico e aspetti di imaging

2016

Describe the clinical use of coronary CT and the characteristic aspects of imaging in the stable patient.

TC coronaricaSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Cardiac Magnetic Resonance with Delayed Enhancement of the Right Ventricle in patients with Left Ventricle primary involvement: diagnosis and evaluat…

2020

: Cardiac Magnetic Resonance (CMR) allows an accurate Right Ventricle (RV) assessment that could be of great relevance in diseases causing inflammation or fibrosis. The aim of this study was to evaluate the concomitant involvement of the RV in patients with delayed enhancement (DE) of the Left Ventricle (LV-DE) using CMR. We retrospectively enrolled 95 (male n. 66; age 55±18years; BMI 26±5kg/m2) consecutive patients with LV-DE who underwent a CMR (Achieva 1.5 T, Philips) for different indications: post-ischemic dilated cardiopathy (PDM), hypertrophic cardiomyopathy (HCM), myocardial infarction (MI), myocarditis/pericarditis (MP) and congenital heart disease (CD). We assessed the presence an…

AdultHeart Defects CongenitalMaleMagnetic Resonance SpectroscopyHeart VentriclesStroke VolumeMiddle AgedDelayed EnhancementMagnetic Resonance ImagingRight VentricleHumansCardiac Magnetic ResonanceCardiomyopathiesSettore MED/36 - Diagnostica Per Immagini E RadioterapiaLeft VentricleAgedRetrospective StudiesActa bio-medica : Atenei Parmensis
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Studio quantitativo della densità ossea dell’ottava vertebra toracica in pazienti sottoposti a TC del cuore

2016

The location of vertebral fractures due to osteoporosis is more frequent in the middle thoracic tract (T8) and in the thoraco-lumbar junction (T12-L1): the T8 vertebra is included in the CT scan volume of the heart. The purpose of the study is to evaluate the density T8 bone in relation to cardiovascular risk factors and the severity of the pathology found in the CT of the heart.

densità ossea TC cuoreSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Direct and indirect involvement of HCV infection in the pathogenesis of myocardial fibrosis in Thalassemia Major

2014

Cardiac MR Diagnostic procedure
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VALUTAZIONE DEL GRASSO EPICARDICO MEDIANTE TC

2021

grasso epicardico TC del cuoreSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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A mistaken case of non-q wave acute infarction

2012

Over the last few years, enormous progress has been made in Cardiovascular imaging. Myocarditis is today an underdiagnosed cause of acute sudden death, heart failure, and chronic dilated cardiomyopathy. Its diagnosis is frequently missed or delayed and it can simulate an acute coronary syndrome because of its clinical presentation and elevation of cardiac enzymes. Cardiac Magnetic Resonance has become the leading modality for its noninvasive diagnosis, and it often replaces endomyocardial biopsy in clinical practise.

Myocardial infarctionSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Ruolo della Cardio TC in pazienti con aneurisma dell’aorta ascendente.

2016

The aim of our study is to evaluate the diagnostic accuracy of cardio CT (CTC) in patients with ascending aortic aneurysm displayed at Transthoracic Echocardiography (ETT).

Settore MED/36 - Diagnostica Per Immagini E RadioterapiaCardio-TC aneurisma aorta
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TRANS-FUSIMO: preliminary in-vivo animal results of MR-guided focused ultrasound of liver under respiratory motion

2019

Purpose: Treating liver tumors using Focused Ultrasound (FUS) is a great challenge. Prior to human applications, an in-vivo animal trial using the TRANS-FUSIMO treatment system (TTS) is ongoing in order to evaluate the safety and the technical efficacy and efficiency of generating predefined necrotic lesions. Methods and Materials: The trial includes a crossbred porcine model of thirty large white swine (all females; 55-85Kg) that will be treated using the TTS under general anaesthesia with intubation. All treatments haven been performed under ventilator-controlled breathing and using an improved non-clinical prototype FUS transducer integrated with a 1,5T MRI unit; a set of interventional …

focused ultrasound liver motion tracking interventional radiology interventional magnetic resonance imagingSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Imaging evaluation of cardiac stem cells transplantation

2012

Cardiovascular Disease is the number one cause of death in the World. Although advances in treatment and intervention have reduced the mortality rate in patients with coronary artery disease, the number of patients with refractory myocardial ischemia and congestive heart failure is rapidly increasing. “Cellular therapy” represents an important new approach in the treatment of cardiovascular disease and the scientific community needs to establish not only the appropriate type and timing of cellular administration but also the diagnostic gold standard to better enable the study of subjects before and after cellular therapy

cells transplantationSettore MED/36 - Diagnostica Per Immagini E RadioterapiaImaging
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Quantificazione del grasso epicardico mediante TC del cuore: associazione con i fattori di rischio cardiovascolare e con l'aterosclerosi coronarica

2014

grasso epicardico TC del cuoreSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Prevalenza delle anomalie coronariche in 4000 pazienti con sospetta malattia coronarica sottoposti a TC del cuore

2016

The aim of this work is to retrospectively study the prevalence of coronary abnormalities in a large population of patients undergoing CT of the heart.

anomalie coronariche TCSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Quantificazione del tessuto adiposo epicardico in Calcium Score e Cardio-TC: confronto tra valori di attenuazione, spessore e volumi.

2016

The aim of the study is to compare the characteristics of epiphonic adipose tissue (TAE) studied using Calcium Score (CS) and Cardio-CT (CTC).

tessuto adiposo epicardico TCSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Integrated non invasive approach to atherosclerosis with cardiac CT and carotid ultrasound in patients with suspected coronary heart disease.

2015

The aim of the study was to compare the atherosclerotic disease in the coronary and carotid arteries in patients who underwent non-invasive imaging for suspected stable coronary artery disease (CAD).

carotid ultrasoundcardiac CTcoronary heart disease
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Combined approach to atrial and ventricular function for assessment of diastole through MRI: Hypertrophic Cardiomyopathy (HCM) vs Healthy Controls (H…

2013

Purpose Methods and Materials Results Conclusion References Personal Information

CongenitalCongenital Imaging sequences MR CardiacMRImaging sequencesSettore MED/36 - Diagnostica Per Immagini E RadioterapiaCardiac
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Patients with acute chest pain, elevated troponin and normal coronary arteries, could be the Cardiovascular Magnetic Resonance advantageous?

2013

Cardiac MR Diagnostic procedure Image verification
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