0000000000239904
AUTHOR
Ml Neamtu
PO-0359 How To Select The Sweat Test Candidate. 10 Years Of Experience In Screening For Cystic Fibrosis In Children
Background Sweat test (ST) remains gold standard in cystic fibrosis (CF) diagnosis. Alarm symptoms are age-related. Aims Retrospective review of cases subjected to ST. Methods Patients were selected by paediatricians, neonatologists, surgeons, based on suggestive symptoms, personal (PH) and familial history (FH). Inclusion criteria: for 0–1 month age group, patients with PH of atelectasis, meconium ileus, intussusception; 1–12 months, recurrent wheezing (RW), failure to thrive (FTT); 1–5 years, previous group symptoms, plus chronic cough/diarrhoea; >5 years, 1–5 years symptoms, plus recurrent pancreatitis/sinusitis. For all age, patients with PH of salty taste of sweat (STS), salt wasting s…
PO-0779 Which Parameters Are Mandatory In Urinary Tract Infection In Children?
Background The protocol of investigations in urinary tract infection (UTI) in children mandatory includes urianalysis, uroculture, reactive C protein (RCP), blood urea (BUN), renal ultrasonography and scintigraphy. Each one of these has limits to perform in children. Aims To establish the correlations between UTI investigations for argumentation the therapeutic decision. Methods Retrospective study of hospitalised paediatric patients for UTI. The study parameters were: age, symptoms, RCP, BUN, uroculture, renal ultrasonography, urinanalysis (leukocytes, nitrites, pH, density, proteins, erythrocytes, ascorbic acid-AA). Results Were studied 243 hospitalised and treated with antibiotics UTI. U…
487 The Influence of Inhaled Corticotherapy on the Growth and Development in Asthmatic Children
Background Inhaled corticotherapy is the main anti-inflammatory controller type therapy in asthmatic children. Impaired growth as a result of long-term corticotherapy remains a disputed issue of topical interest for both endocrinologists, pneumologists and pediatricians. Objective The study evaluates the influence of long term small dose inhaled corticotherapy on growth and somatic development in asthmatic children. Methods Observational analytical study on 2 samples of subjects. The study group: 100 asthmatic children with small dose inhaled corticotherapy (beclomethasone dipropionate Becotide 200–400 µg/day or fluticasone propionate Flixotide 100–300 µg/day), for 24 months therapy. The co…
Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone
BACKGROUND The safe and appropriate use of long-acting beta-agonists (LABAs) for the treatment of asthma has been widely debated. In two large clinical trials, investigators found a potential risk of serious asthma-related events associated with LABAs. This study was designed to evaluate the risk of administering the LABA salmeterol in combination with an inhaled glucocorticoid, fluticasone propionate. METHODS In this multicenter, randomized, double-blind trial, adolescent and adult patients (age, ≥12 years) with persistent asthma were assigned to receive either fluticasone with salmeterol or fluticasone alone for 26 weeks. All the patients had a history of a severe asthma exacerbation in t…
PO-0322 The Effective Dose Of Sodium Bicarbonate In Severe Acute Dehydration And Metabolic Acidosis Due To Acute Diarrhoea In Children
Background Still exist controversies about sodium bicarbonate (SB) effectiveness in metabolic acidosis (MA). The SB dose finally remain at discretion of physician. Aims Proving SB efficiency in severe acute dehydration (SAD) with MA secondary to acute diarrhoea (AD) in children. Methods Retrospective study conducted between May–September 2013, in 0–5 years old patients hospitalised for AD with SAD and MA. We chose the propitious age group and season for acute gastrointestinal pathology. We considered SAD loss >10% of body weight and severe MA pH Results In A Group, at admission, 57,14% presented pH 15; at 4 H, all presented alkalosis. In B Group, at admission, 50% presented severe MA; at 1 …
770 Risk Factors Associated with Anemia and Nutritional Status in Infants
Background Growth assessment is an integral part of infants health. An understanding of anemia risk factors is essential to identify the groups that are more vulnerable. The Aim of the study was to identify the risk factors for malnutrition in the vulnerable age group of 6 to 12 months and to evaluate possible related risk factors with anemia. Methods The cross-sectional study which evaluated 206 infants aged between 6–12 months who attended the Pediatric Clinic during the years 2010–2011 for inadequate growth. Mothers were interviewed to collect informations regarding socioeconomic status and nutrition practices. Nutritional status was evaluated by anthropometric measurements using growth …
549 Prevention of Obesity Through Healthy Nutrition in the First Year of Life
Background Obesity, defined as excess body fat can be diagnosed at 6 months. In children, BMI percentiles are used, defining the overweight between 85–95 and obesity >95. The main predictors of primary obesity in infancy are high birthweight, parental obesity, low total energy expenditure and energy intake (EI). Aim Calculation of optimal EI in infants. Method Calculation of estimated energy requirements (EER) for infants was made according to the formulas: [(89×Gkg)-100]+175 between 0–3 months, [(89×Gkg)-100]+56, between 4–6 months, [(89×Gkg)-100]+22, between 7–12 months. Calculation of fluid requirements was made according to Apert formula: G g /10+200(300). Results Were studied 11 infant…
1712 Serum Electrolytes Variations in Treated Patients with Moderate Asthma Exacerbation
Background Salbutamol induces stimulation of beta 2 -receptors resulting in hypokalemia. Corticosteroids also induce plasma electrolytes variations. Aims To identify blood electrolytes changes following low dose inhaled short-acting beta 2 -agonists; To evaluate if concomitant inhaled corticosteroids treatment can amplify serum electrolytes changes. Methods We analyzed all children admitted for moderate asthma exacerbation during 6 months period. Inclusion criteria: children between 5–18 years of age; PEF >50–75% of predicted value; serum electrolytes normal ranges. Exclusion criteria: previously treated patients with Salbutamol; Salbutamol hypersensitivity; asthma exacerbation severity lev…
565 Reflection on a Case of Dopamine-Responsive Dystonia
Background Characteristic symptoms of Dopamine-responsive dystonia (DRD) are increased muscle tone and Parkinsonian features. Children with DRD are often misdiagnosed. The disorder responds well to treatment with Levodopa. Aim To reflect on a case of DRD. Method Case report of a 13 years old girl misdiagnosed with tetany. Results The girl was hospitalized for opisthotonus, positive Trousseau and Chvostek signs, diagnosed as tetany. The laboratory analysis have shown: normal serum of calcium (2.28 mmol/l), normal serum of magnesium (0.80 mmol/l), normal serum of phosphor (1.26 mmol/l), normal alkaline phosphatase (261 u/l) and normal PTH (27.9 pg/ml). Although the initial evolution was favor…
685 Food Allergy - Gastro-Esophageal Reflux Disease Association in Infants
Background Cow’s milk allergy is considered to be the first and most common type of allergy during early infancy. Gastro-esophageal reflux disease and cow’s milk allergy are two different diseases with common clinical features. The aim of the study was to evaluate the clinical data in relation with gastroesophageal reflux and cow’s milk allergy in infants. Material and Methods The prospective study includes 36 infants aged between 2–6 months who attended at Pediatric Clinic during the year 2011 for the clinical evocative manifestations of gastroesophageal reflux. Study protocol includes: clinical criteria, familial/personal atopic features, mother diet, duration of breastfeeding, infant for…
966 The Nonthyroidal Illness Syndrome in Septic Children
Backgroud The interpretation of thyroid function tests in the PICU patients can be difficult because thyroid hormone concentrations are affected by nonthyroidial stresses. Most patients fall into sick euthyroid syndrome or nonthyroidal illness syndrome (NTIS). The TH therapy during critical illness remains controversial. Aim To evaluate the NTIS in septic children. Method The prospective study conducted on 65 patients admitted in PICU during 12 months period. Inclusion criteria: age > 1 month, admission for critical illness, treatment with corticosteroids, no (documented) history of thyroid pathology. The patients were divided into 2 groups: sepsis and non-sepsis group (dehydration, poisoni…
756 The Effectiveness of RDW-CV in Differentiating Microcytic Anemia
Backround: Iron deficiency anemia (IDA) and thalassemia are the most common microcytic anemia in children. Sometimes, expensive or invasive investigations are necessary for their distinction. Red cell distribution - coefficient variation (RDW-CV) is a new generation marker more often used in differentiating IDA from thalassemia. A number of hematological indices are also useful (Mentzer, Shine&Lal, Green&King, Ricerca). Aim To demonstrate the effectiveness RDW - CV in differentiating microcytic anemia. Method Retrospective study conducted on a total of 215 patients with microcytic anemia. Criteria for study group selection: MCV and Hb below the minimum age reference (mild anemia, Hb between…