0000000000269547

AUTHOR

Laura M. Ilharco

0000-0001-6994-1464

showing 7 related works from this author

Enhanced Mechanical Properties in Organofluorosilica Thin Films

2008

Fluorinated hybrid organic-inorganic silicates (ORMOSIL) thin films display exceptional mechanical properties in terms of both hardness and elastic modulus that can be finely tuned by varying the angular velocity of the spin coating process. Hence, as traditional alkyl-modified silica xerogels generally show poor mechanical behavior, these materials offer a solution to a major limitation to applicability of ORMOSIL-based films.

Spin coatingMaterials scienceArticle Subjectlcsh:Technology (General)lcsh:T1-995General Materials ScienceAngular velocityThin filmComposite materialOrmosilElastic modulusJournal of Nanomaterials
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Neuroprotective and Mitoprotective Effects of Lemon IntegroPectin on SH-SY5Y Cells

2021

AbstractLemon IntegroPectin obtained via hydrodynamic cavitation of organic lemon processing waste in water shows significant neuroprotective activity in vitro, as first reported in this study investigating the effects of both lemon IntegroPectin and commercial citrus pectin on cell viability, cell morphology, reactive oxygen species (ROS) production and mitochondria perturbation induced by treatment of neuronal SH-SY5Y human cells with H2O2. Mediated by ROS including H2O2 and its derivatives, oxidative stress alters numerous cellular processes, including mitochondrial regulation and cell signaling, propagating cellular injury that leads to incurable neurodegenerative diseases. These result…

chemistry.chemical_classificationReactive oxygen speciesCell signalingSH-SY5YchemistrymedicineViability assayMitochondrionmedicine.disease_causeCell morphologyNeuroprotectionOxidative stressCell biology
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New neuroprotective effect of lemon integropectin on neuronal cellular model

2021

Lemon IntegroPectin obtained via hydrodynamic cavitation of organic lemon processing waste in water shows significant neuroprotective activity in vitro, as first reported in this study investigating the effects of both lemon IntegroPectin and commercial citrus pectin on cell viability, cell morphology, reactive oxygen species (ROS) production, and mitochondria perturbation induced by treatment of neuronal SH-SY5Y human cells with H2O2. Mediated by ROS, including H2O2 and its derivatives, oxidative stress alters numerous cellular processes, such as mitochondrial regulation and cell signaling, propagating cellular injury that leads to incurable neurodegenerative diseases. These results, and t…

Cell signalingantioxidantPhysiologyhesperidin;Antioxidant Flavonoids Hesperidin Mitochondria Neu-roprotective Neurological disease Oxidative stress PectinClinical BiochemistryRM1-950antioxidant;MitochondrionCell morphologymedicine.disease_causeBiochemistryNeuroprotectionArticleflavonoids;03 medical and health sciences0302 clinical medicinehesperidinmedicineoxidative stressViability assayneurological diseaseMolecular Biology030304 developmental biologychemistry.chemical_classificationpectinoxidative stress;neuroprotective;0303 health sciencesReactive oxygen speciespectin;neuroprotectiveCell BiologyCell biologymitochondriachemistryneurological disease;flavonoidsTherapeutics. PharmacologyCellular model030217 neurology & neurosurgeryOxidative stress
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Pectin: A Long-Neglected Broad-Spectrum Antibacterial.

2020

First reported in the late 1930s and first partly explained in 1970, the antibacterial activity of pectin remained almost ignored until the late 1990s. The concomitant emergence of research on natural antibacterials and on new usages of pectin polysaccharides, including those in medicine widely researched in Russia, has led to a renaissance of research in the physiological properties of this uniquely versatile polysaccharide ubiquitous in plants and fruits. Collecting scattered information, this study provides an updated overview on the subtle factors affecting the behaviour of pectin as antimicrobial. Less degraded pectin extracted via acid-free routes, we argue in the conclusions, will so…

Polymicrobial infection2019-20 coronavirus outbreakfood.ingredientPectinSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Biocompatible MaterialsMicrobial Sensitivity TestsBiology01 natural sciencesBiochemistrypectin polysaccharidesBroad spectrumfoodDrug DiscoveryCitrus PectinFood scienceGeneral Pharmacology Toxicology and PharmaceuticsPharmacologypectinBacteria010405 organic chemistryOrganic ChemistryThe Renaissancefood and beveragesAntimicrobialcitrus pectin0104 chemical sciencesantibacterial agents antimicrobial agents polysaccharides pectin citrus pectinAnti-Bacterial Agents010404 medicinal & biomolecular chemistryantibacterialMolecular MedicineantimicrobialPectinsChemMedChem
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Integral Extraction of Opuntia ficus-indica Peel Bioproducts via Microwave-Assisted Hydrodiffusion and Hydrodistillation

2019

The microwave-assisted hydrodiffusion extraction process affords high quality pectin and betanin from the peel of red and green Opuntia ficus-indica fruits under mild conditions. An aqueous mixture of valued bioproducts is readily obtained from the fruit peel cell water itself, without any water addition. The integral extract can be used as such to formulate nutraceutical beverages and products or, upon straightforward separation, to isolate pectin and betanin devoid of chemical contaminants suitable as ingredients for products ranging from food and beverage to cosmetic and pharmaceutical sectors. Betanin shows exceptional stability thanks to the high amounts of antioxidant polyphenols in t…

food.ingredientPectinSettore CHIM/10 - Chimica Degli AlimentiGeneral Chemical EngineeringOpuntia ficus02 engineering and technology010402 general chemistry01 natural sciencesMicrowave assistedBetaninchemistry.chemical_compoundfoodBioproductsEnvironmental ChemistryChemical Engineering (all)Renewable EnergyFood scienceBetaninSustainability and the EnvironmentRenewable Energy Sustainability and the EnvironmentChemistryChemistry (all)Extraction (chemistry)Prickly pearOpuntiaGeneral Chemistry021001 nanoscience & nanotechnologyPectin0104 chemical sciencesAnti-inflammatory; Antioxidant; Betanin; Biophenol; Opuntia; Pectin; Prickly pear; Chemistry (all); Environmental Chemistry; Chemical Engineering (all); Renewable Energy Sustainability and the EnvironmentBiophenolAnti-inflammatoryAntioxidant0210 nano-technology
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Economic and Technical Feasibility of Betanin and Pectin Extraction from Opuntia ficus-indica Peel via Microwave-Assisted Hydrodiffusion

2019

Investigating the feasibility of betanin and pectin extraction from Opuntia ficus-indica peel via microwave-assisted hydrodiffusion and gravity, this study identifies selected important economic and technical aspects associated with this innovative production route starting from prickly pear fruit discards. Which benefits would be derived from this process? Would production be limited to Opuntia-growing countries or, likewise to what happens with dried lemon peel chiefly imported from Argentina, would production take place abroad also? Can distributed manufacturing based on clean extraction technology compete with centralized production using conventional chemical processes?

Opuntia ficus-indicafood.ingredientSettore CHIM/10 - Chimica Degli AlimentiPectinGeneral Chemical EngineeringOpuntia ficusbetainMicrowave assistedArticlelcsh:Chemistrychemistry.chemical_compoundfoodBetanin and Pectin Extraction Opuntia ficus-indica Microwave-Assisted HydrodiffusionbioeconomyBetaninpectinLemon peelExtraction (chemistry)circular economyGeneral ChemistryPulp and paper industryTechnical feasibilitylcsh:QD1-999chemistryPrickly Pear Fruitmicrowave assisted hydrodiffusionEnvironmental science
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Polymers of Limonene Oxide and Carbon Dioxide: Polycarbonates of the Solar Economy

2018

Limonene epoxide (1,2 limonene oxide) readily reacts with carbon dioxide in a ring opening copolymerization reaction with insertion of CO2 and formation of polycarbonates of exceptional chemical and physical properties. Both poly(limonene carbonate) and poly(limonene dicarbonate) can be synthesized using low cost Zn or Al homogeneous catalysts. This study addresses selected relevant questions concerning the technical and economic feasibility of limonene and carbon dioxide polymers en route to the bioeconomy.

General Chemical EngineeringOxidepoly(limonene carbonate)Epoxidebiopolymers010402 general chemistry01 natural sciencesCatalysislcsh:Chemistrychemistry.chemical_compoundLimonene oxideCopolymerOrganic chemistryChemical Engineering (all)Dicarbonateorganic_chemistrybioeconomychemistry.chemical_classificationLimonene010405 organic chemistrylimonene epoxideChemistry (all)General ChemistryPolymer0104 chemical scienceschemistryChemical engineeringlcsh:QD1-999PerspectiveCarbon dioxideSettore CHIM/07 - Fondamenti Chimici Delle TecnologieChemistry (all); Chemical Engineering (all)
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