0000000000908539
AUTHOR
Salvatore Accomando
showing 127 related works from this author
Un caso inusuale di anemia emolitica
2007
Ipertransaminasemia: analisi di una casistica di bambini ricoverati presso la UO "Clinica Pediatrica" Ospedale dei Bambini "G. Di Cristina" di Palerm…
2015
Infezione da EBV e malattia di Stevens-Johnson.
2008
Celiac Disease: a widespread emerging condition in mediterranean countries.
2010
Anemie emolitiche: analisi etiologica di una casistica annuale.
2010
OBSTRUCTED DEFECATION SYNDROME AND CHRONIC CONSTIPATION: CLINICAL AND SURGICAL ANALYSIS AND PSYCHOLOGICAL IMPLICATIONS
2022
Chronic constipation and Obstructed defecation Syndrome (ODS) represent a high-incidence pathological status that severely compromise of Quality of Life (QoL). Our multidisciplinary study is aimed to investigate how the resolution of ODS by surgical technique can improve long-term clinical symptoms and the state of physical and mental health and QoL, focusing on the dual interaction between psyche and intestine Chronic constipation and Obstructed Defectaion Syndrome represent a high-incidence pathological status that severely compromise of Quality of Life. Our multidisciplinary study is aimed to investigate how the resolution of ODS by surgical technique can improve long-term clinical sympt…
Un caso inusuale di malattia emolitica.
2007
Malattia di Kawasaki tipica resistente a immunoglobuline e steroidi: uso di Infliximab.
2009
RABDOMIOLISI IN CORSO DI INFEZIONE DA VIRUS PARAINFLUENZALE TRATTATA CON PARACETAMOLO
2009
Dietary habits in children of immigrant families from developing countries: an Italian multicentre study
2006
Objectives. The aim of this study was to investigate the dietary habits of immigrant children who come to Italy from developing countries, and of their families. Methods. A multicentre cross-sectional study was carried out from Jan. 1st 2003 to Dec. 31st 2004. The study population comprised 1284 immigrant mothers, 629 infants, and 767 children with more than 2 years of age. A structured questionnaire was employed to inquire retrospectively on dietary habits and, on breastfeeding, complementary breastfeeding, bottle-feeding and weaning. Results. Exclusive and complementary breastfeeding was more frequent and of longer duration among immigrant infants than Italian infants, but not compared to…
Gastroenterite Eosinofila ed asa triad.
2005
I polimorfismi del gene IRGM sono associati al comportamento fistolizzante della malattia di Crohn.
2008
Un problema emergente: il rachitismo carenziale nei bambini adottati dall’estero.
2006
Sclerodermia sistemica: descrizione di un caso in età pediatrica.
2007
Rabdomiolisi in corso di infezione da virus parainfluenzale: descrizione di un caso in età pediatrica.
2009
Studio neurofisiologico dei potenziali evocati uditivi e visivi in bambini affetti da malattia di Kawasaki: contributo personale.
2007
Immunization status of internationally adopted children in Italy
2006
An increasing number of internationally adopted children is coming to Italy, and their immunization status is unknown. We evaluated the immunization status of such children in Palermo, Italy. We searched for the presence of a BCG scar in 88 children, 49 boys and 39 girls (mean age 76+/-32 months), most of whom (98%) came from Eastern Europe. Presence of BCG scar was observed in 59 (67.1%) of them, included five children without any pre-adoptive medical records. Twenty-three out of 29 children without any evidence of BCG scar were tested by Mantoux. Seven (30.4%) of 23 were tuberculin positive and diagnosed as having latent tuberculosis infection. We also examined immunization status against…
MALATTIA DI KAWASAKI: MODALITA’ DI ESORDIO E DECORSO CLINICO
2007
La Malattia Celiaca: Nuove implicazioni in una antica condizione
2006
Utilizzo dei latti speciali: uso ed abuso.
2009
Un problema emergente : il rachitismo carenziale nei bambini adottati
2006
INFLIXIMAB IN THE TREATMENT OF PEDIATRIC IBD: A SINGLE CENTRE EXPERIENCE
2010
The global village of celiac disease
2004
In the last years our knowledge on epidemiology of celiac disease has increased: there is a wide spectrum of its clinical presentation (classical, atypical, silent and latent forms of celiac disease), and of its pathological mucosal intestinal features, which range from early and mild pictures to severe villous atrophy (Marsh stages). In addition, a strong genetic component, associated with the susceptibility to the disease (HLA and non HLA genes), has been found. This knowledge, together with the availability of new high sensitive and specific serological tests (antigliadin, antiendomysium and antitransglutaminase antibodies), has led us to the realization that celiac disease is the most c…
Deficit di G6PD: diagnosi fenotipica e genetica. Prevalenza e caratterizzazione molecolare delle varianti genetiche nella popolazione pediatrica sici…
2015
INFLIXIMAB THERAPY IN MANAGING PEDIATRIC IBD
2012
Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy.
2008
AIM: To investigate gene variants in a large Italian inflammatory bowel disease (IBD) cohort, and to analyze the correlation of sub-phenotypes (including age at diagnosis) and epistatic interaction with other IBD genes. METHODS: Total of 763 patients with Crohn's disease (CD, 189 diagnosed at age < 19 years), 843 with ulcerative colitis (UC, 179 diagnosed < 19 years), 749 healthy controls, and 546 healthy parents (273 trios) were included in the study. The rs2241880 [autophagy-related 16-like 1 (ATG16L1)], rs11209026 and rs7517847 [interleukin 23 receptor (IL23R)], rs2066844, rs2066845, rs2066847 (CARD15), rs1050152 (OCTN1), and rs2631367 (OCTN2) gene variants were genotyped. RESULTS: The f…
1001 infusions of Infliximab in children with IBD: a 10 years study from the Italian Society of Pediatric Gastroenterology Hepatology and Nutrition
2009
Corticosteroidi nella HSP: l’enigma continua…
2009
Changes in immunohistochemical levels and subcellular localization after therapy and correlation and colocalization with CD68 suggest a pathogenetic …
2011
In an earlier work, the role of heat shock protein (Hsp60) in the pathogenesis of ulcerative colitis (UC) was suggested by its significant increase in the pathological mucosa parallel with an increase in inflammatory cells. More data in this direction are reported in this work. We analyzed by immunohistochemistry biopsies of colon tissue from 2 groups of patients with UC and treated with either 5-aminosalicylic acid (5-ASA) alone or in combination with a probiotic. We looked for inflammatory markers and Hsp60. Both the treatments were effective in reducing symptoms but the group treated with both 5-ASA and probiotics showed better clinical results. Amelioration of symptoms was associated wi…
Neuropatia periferica in corso di infezione da Helicobacter pylori e Mycoplasma Pneumoniae.
2008
Utilità degli ASCA nel follow up della malattia di Crohn.
2005
Manifestazioni extrapolmonari da Mycoplasma Pneumoniae.
2009
Un caso di polmonite nosocomiale in un paziente appendicectomizzato
2009
Multiple food intolerance or refractory celiac sprue?
2006
Infliximab and emerging biological treatment for pediatric Crohn’s disease.
2009
The pediatric endoscopy practice in Italy: A nationwide survey on behalf of the Italian society of pediatric gastroenterology, hepatology and nutriti…
2019
Nuovi markers sierologici in corso di Malattia Infiammatoria Cronica Intestinale [New serological markers in IBD diagnosis]
2011
IBD diagnosis, in spite of clinically suspected form, lies on upper and lower endoscopy. Nevertheless endoscopic investigation is an invasive diagnostic tool especially in pediatric age. For this reason pediatricians are looking for mini invasive diagnostic algorithm in order to avoid unnecessary endoscopy. Up to date, while fecal calprotectin is a well established and confirmed intestinal inflammatory marker, on the other hand, new perspectives are opening on serological markers helpful in suspected diagnosis of IBD
Coeliac disease and depression: two related entities?
2005
Rilievi clinici su una casistica di 118 bambini adottati dall’estero.
2006
Vantaggi della RMN intestinale a doppio contrasto nel monitoraggio del Crohn Pediatrico Fistolizzante
2009
Generalized anasarca as way of presentation of severe protein losing enteropathy.
2009
Dalla FUO alla sindrome da iper-IgD (HIDS).
2008
Hsp60 and Hsp10 increase in colon mucosa of Crohn's disease and ulcerative colitis.
2010
The purpose of this work was to determine in colon mucosa of Crohn’s disease (CD) and ulcerative colitis (UC) in relapse: a) the levels of the chaperonins Hsp60 and Hsp10; b) the quantity of inflammatory cells; and c) if the levels of chaperonins parallel those of inflammation cells. Twenty cases of CD and UC and twenty normal controls (NC) were studied using immunohistochemistry, Western blotting and immunofluorescence. Immunohistochemically, Hsp60 and Hsp10 were increased in both inflammatory bowel diseases (IBD) compared to NC. These results were confirmed by Western blotting. Hsp60 and Hsp10 occurred in the cytoplasm of epithelial cells in CD and UC but not in NC. Hsp60 and Hsp10 co-loc…
Efficacy of adalimumab as second-line therapy in a pediatric cohort of Crohn’s disease patients who failed infliximab therapy: the Italian Society of…
2019
Patrizia Alvisi,1 Serena Arrigo,2 Salvatore Cucchiara,3 Paolo Lionetti,4 Erasmo Miele,5 Claudio Romano,6 Alberto Ravelli,7 Daniela Knafelz,8 Stefano Martelossi,9 Graziella Guariso,10 Salvatore Accomando,11 Giovanna Zuin,12 Costantino De Giacomo,13 Lucio Balzani,14 Monia Gennari,15 Marina Aloi3 On behalf of the SIGENP IBD Working Group 1Pediatric Gastroenterology Unit, Pediatric Department, Maggiore Hospital, Bologna, Italy; 2Pediatric Gastroenterology and Endoscopy Unit, G Gaslini Children&rsquo;s Hospital, Genoa, Italy; 3Pediatric Gastroenterology and Liver Unit, Sapienza University of Rome, Rome, Italy; 4Gastroenterology and Nutrition Unit, Meyer Children&rsquo;s Hospital, Florenc…
Biochemical markers in Celiac disease.
2009
Celiac Disease is a worldwide spread condition affecting 1:100-1:200 individuals. It is a permanent food intolerance to ingested gluten in genetically predisposed subjects. In this review we analyze the biochemical markers of the disease going from laboratory findings to histology passing through genetics. Gluten intolerance is a unique model of autoimmune disease in which we can recognize the main environmental factor (gluten) and the more complex genetic background. In additional way, serological markers for monitoring the disease and a safe and effective therapy (gluten free diet) are also available. In deed the environmental factor such as gluten intake is necessary to trigger the disea…
Duodenal Giardiasis: a diagnosis we should not neglect
2008
HOME CARE AND AUTO INFUSION IN PEDIATRIC HAEMOPHILIAC PATIENTS
2004
Rilievi clinici su 139 bambini adottati dall’estero
2006
Miositi dell'età pediatrica: Analisi di una casistica biennale.
2015
Milk intolerance: a big trouble for little patients.
2008
TNFalfa,IFN gamma, IL-10 gene polymorphisms in a sample of Sicilian patients with coeliac disease
2005
Studio multicentrico italiano sui problemi scolastici del bambino immigrato.
2006
P609 New and old criteria for diagnosing celiac disease
2019
Background CD is an immune-mediated systemic disease elicited by gluten and related prolamines, it affects genetically susceptible individuals and it is characterized by the presence of gluten-dependent clinical manifestations, CD-specific antibodies, HLA-DQ2 or HLA-DQ8 haplotypes and enteropathy. According to the guidelines published by ESPGHAN in 2012, it is possible to diagnose celiac disease without intestinal biopsy, in symptomatic children and adolescents with very high levels of transglutaminases type-2 antibodies and positive HLA DQ2/DQ8. Aims The aim of our study is to analyse two groups of patients: one in which diagnosis was based on the new ESPGHAN criteria, and another based on…
DOUBLE BLIND PLACEBO CONTROLLED FOOD CHALLENGE USEFUL TO DISCONFIRM OVER ESTIMATED DIAGNOSIS OF CMPA IN CHILDREN
2009
Mycoplasma Pneumoniae: analisi di una casistica annuale.
2008
Increased Percentages of Tumor Necrosis Factor-α+/Interferon-T+Lymphocytes and Calprotectin+/Tumor Necrosis Factor-A+ Monocytes in Patients with Acut…
2012
In vivo exposure to microorganisms resident in the oral cavity is considered as a possible cause of Kawasaki disease (KD), and some epitopes derived from streptococci display homology with Factor H of Complement. Additionally, calprotectin, a major calcium binding protein released by neutrophils and activated monocytes, could be directly involved in endothelial damage occurring in KD. The aim of our study is to evaluate the percentages of IFN-γ+ and/or TNF-α+ lymphocytes and double positive calprotectin/TNF-α monocytes (CD14+) after in vitro stimulation with streptococcal- and/or Factor H-derived peptides, in patients with acute KD. Peripheral Blood Mononuclear Cells (PBMCs) obtained from …
Internationally adopted children: a new challenge for pediatricians.
2006
Children adopted from abroad by Italian families have increased during the last years. Since 2001 to 2004 they have been more than 10,000, mainly from Eastern Europe, and all indications suggest that they will continue to increase. Most of the internationally adopted children reside in orphanage before adoption where they may experience malnutrition, exposure to infectious diseases, environmental deprivation, neglect. Moreover, their pre-adoptive records are scarcely reliable and their immunization status is not always adequate. The most common long-term problems of internationally adopted children concern developmental and scholastic delay especially if they come from a long and severely d…
Trattamento delle piastrinopenie: esperienza annuale
2010
Analysis of risk and prognostic factors in a population of pediatric patients hospitalized for acute malnutrition at the Chiulo hospital, Angola
2021
Abstract Background Malnutrition is a multifactorial pathology in which genetic, epigenetic, cultural, environmental, socio-economic factors interact with each other. The impact that this disease has on the health of children worldwide is dramatic. Severe acute malnutrition in particular is a disease affecting nearly 20 million preschool children worldwide, most of them in Africa and South East Asia. Objectives This work aims to investigate potential prognostic factors in the clinical evolution of acute malnutrition and potential risk factors for the development of the disease. Methods Our study was carried out at the “Hospital da Missão Catolica do Chiulo”, in Angola, where the NGO Doctors…
DFGI: Dinamica osservazione di una casistica pediatrica
2015
Real-Life Use of Biosimilars in Pediatric Inflammatory Bowel Disease: A Nation-Wide Web Survey on Behalf of the SIGENP IBD Working Group
2022
Objective: The aim was to assess the awareness and real-life use of biosimilars in inflammatory bowel disease (IBD) among the members of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP). Methods: An anonymous web survey involving all SIGENP IBD units which can prescribe biosimilars was conducted between July 1st and December 1st, 2020. The questionnaire included 18 questions addressing the most relevant aspects of biosimilars in pediatric IBD, i.e., advantages, disadvantages, costs, traceability, general knowledge, and real-life use. A descriptive analysis of responses was performed. Results: Responses came from 26 pediatric IBD units in Italy, with repre…
School problems among immigrant students
2004
p Natural polyphenols as anti-inflammatory agents p
2009
Celiac Disease is a worldwide spread condition affecting 1:100-1:200 individuals. It is a permanent food intolerance to ingested gluten in genetically predisposed subjects. In this review we analyze the biochemical markers of the disease going from laboratory findings to histology passing through genetics. Gluten intolerance is a unique model of autoimmune disease in which we can recognize the main environmental factor (gluten) and the more complex genetic background. In additional way, serological markers for monitoring the disease and a safe and effective therapy (gluten free diet) are also available. In deed the environmental factor such as gluten intake is necessary to trigger the disea…
Celiac disease: to screen or not to screen the general population?
2005
Effectiveness and safety of biologics in pediatric inflammatory boweldisease: Real-life data from the Sicilian Network
2019
Background: Biological therapies have modified the disease course of pediatric inflammatory bowel disease (IBD) and are routinely used in clinical practice. Our observational study aims to evaluate effectiveness and safety of biologics in IBD. Method: Clinical benefit and safety data of 93 children with IBD, receiving biologics (Infliximab – IFX, Adalimumab – ADA, Golimumab – GOL) from January 2013 to December 2017, were extracted from the cohort of the Sicilian Network of IBD. Results: Among 87 children aged 7–17 years (63 Crohn's disease [CD], 24 Ulcerative colitis [UC]), 101 out of 108 biologic treatments were considered. Evaluation of 74 biologic treatments in CD patients at 26, 52, 104…
ROLE OF NAKED CUTICLE HOMOLOG 1 GENE ON CHR 16Q12 IN INFLAMMATORY BOWEL DISEASE.
2010
Association Between Previously Identified Disease Loci At Chr12q15 and Chr1p36 and UC in Italian Population
2009
797 Infliximab in the Treatment of Pediatric Ibd: A Single Centre Experience
2010
Background and aims: The biological treatment of IBD acts on different stages of immunophysiopathological processes of the disease. We describe evolution and clinical response to Infliximab in paediatric patients affected by IBD diagnosed and followed at our centre. Methods: In the last triennial period at our Department of Paediatrics in Palermo 53 infusions of Infliximab were administrated to our patients affected by severe forms of IBD. All patients but one were affected by several forms of CD. Only one child was affected by U.C. associated to pyoderma gangrenosum. The total number of infusions were administrated according the ACCENT 1 study at a dose of 5 mg/Kg. All the infusions were p…
Serological Screening of Celiac Disease: Choosing the best tests under two years.
2005
Infliximab administration effective in the treatment of refractory Kawasaki Disease
2010
TRATTAMENTO CON INFLIXIMAB IN UN LATTANTE CON MALATTIA DI KAWASAKI RESISTENTE ALLE TERAPIE CONVENZIONALI
2009
MYCOPLASMA PNEUMONIAE INFECTIONS IN PAEDIATRIC AGE: CLINICAL VARIABILITY
2013
TNFalpha, IFNgamma and IL-10 gene polymorphisms in a sample of Sicilian patients with coeliac disease.
2005
Coeliac disease is associated with DQ2 and DQ8 alleles, but other genes also confer an additional genetic risk.Defining whether the genetic profiles of interleukin-10, tumour necrosis factor alpha and interferon gamma are associated with an increased coeliac disease risk.The functionally gene polymorphisms of tumour necrosis factor alpha (-308G/A), interferon gamma (+874T/A) and interleukin-10 (-1082G/A) were typed using sequence specific primer-polymerase chain reaction in 110 Sicilian coeliac disease patients and in 220 Sicilian healthy controls.No differences in genotype frequencies of interleukin-10 polymorphisms were found between coeliac disease patients and healthy controls. A signif…
Changes in immunohistochemical levels and subcellular localization after therapy and correlation and colocalization with CD68 suggest a pathogenetic …
2011
In an earlier work, the role of heat shock protein (Hsp60) in the pathogenesis of ulcerative colitis (UC) was suggested by its significant increase in the pathological mucosa parallel with an increase in inflammatory cells. More data in this direction are reported in this work. We analyzed by immunohistochemistry biopsies of colon tissue from 2 groups of patients with UC and treated with either 5-aminosalicylic acid (5-ASA) alone or in combination with a probiotic. We looked for inflammatory markers and Hsp60. Both the treatments were effective in reducing symptoms but the group treated with both 5-ASA and probiotics showed better clinical results. Amelioration of symptoms was associated wi…
Un caso di malattia di Kawasaki refrattaria
2021
Novità in tema di Mycoplasma e Chlamydia
2009
Intolleranza al latte: nuovo algoritmo diagnostico.
2005
PA1 INFLIXIMAB AND TOPICAL TACROLIMUS ADMINISTRATION EFFECTIVE IN THE TREATMENT OF PYODERMA GANGRENOSUM
2009
Infliximab administration effective in the treatment of refractory Kawasaki Disease
2010
A Propensity Score-matched Comparison of Infliximab and Adalimumab in Tumour Necrosis Factor-α Inhibitor-naïve and Non-naïve Patients with Crohn's Di…
2019
Background and aims There is an unmet need to better understand the effectiveness of different biologics in inflammatory bowel diseases. We aimed at performing a multicentre, real-life comparison of the effectiveness of infliximab [IFX] and adalimumab [ADA] in Crohn's disease [CD]. Methods Data of consecutive patients with CD treated with IFX and ADA from January 2013 to May 2017 were extracted from the cohort of the Sicilian Network for Inflammatory Bowel Disease. We used propensity score-matching accounting for the main baseline characteristics in TNF-α inhibitor-naive and non-naive patients. Results A total of 632 patients [735 total treatments] were included. Among naive patients, a cli…
Infliximab in children with inflammatory bowel disease in Italy: Efficacy.
2007
Local Complications And Adverse Drug Reactions In Paediatric Inflammatory Bowel Disease
2014
Analysis of functionally Relevant Single nucleotide polymorphisms of TNFα and of IFN-gamma in Celiac Disease
2004
CUTANEOUS MANIFESTATIONS IN PEDIATRIC COELIAC DISEASE
2013
PO-0994 Ltri In Paediatrics: Analysis Of An Annual Survey
2014
Background and aims Lower tract respiratory infections (LTRI) are very frequent in paediatric population. We collected epidemiological, etiological and clinical data and correlated them to some variables. Methods We performed an observational study of all children with a LTRI, admitted to our Paediatric Unit from February 2013 to January 2014. The population was grouped in three classes of ages (0–2yr, 3–6yr, >6yr). All patients underwent to a questionnaire focused on exposition to protective and risk factors for respiratory diseases. Results 83 children were included. We grouped them according to discharge diagnosis and analysed the distribution for ages, sex and season of onset. At the ad…
Utilità del test di provocazione orale in doppio cieco nell'esclusione della diagnosi di APLV
2009
A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease
2007
BACKGROUND: Treatment of celiac disease (CD) is based on the avoidance of gluten-containing food. However, it is not known whether trace amounts of gluten are harmful to treated patients. OBJECTIVE: The objective was to establish the safety threshold of prolonged exposure to trace amounts of gluten (ie, contaminating gluten). DESIGN: This was a multicenter, double-blind, placebo-controlled, randomized trial in 49 adults with biopsy-proven CD who were being treated with a gluten-free diet (GFD) for > or =2 y. The background daily gluten intake was maintained at < 5 mg. After a baseline evaluation (t0), patients were assigned to ingest daily for 90 d a capsule containing 0, 10, or 50 mg glute…
Amido di mais nel management della dumping syndrome: una lezione maturata dalla malattia di Von Gierke.
2008
Analysis of functionally relevant single nucleotide polymorphisms of TNF alfa and IFN gamma genes in celiac diseases
2004
Non sempre la MICI viaggia da sola.
2006
Mycoplasma pneumonias distribution, epidemiology and prevalence in a triennial survey.
2005
OBJECTIVES. To evaluate: (1) the incidence of pneumonia monthly distribution; (2) the rate of pneumonitis due to Mycoplasma Pneumoniae; (3) the suitability of choosing an empirical-based antibiotic-therapy; (4) the need of a critical revision of Mycoplasma serological data. PATIENTS AND METHODS. We studied 188 patients admitted to the Palermo University Pediatrics Department, from september 1998 to august 2001, with admission diagnosis of pneumonia. RESULTS. The highest incidence of pneumonia was in december and march as in both months 28 cases occurred in the whole period 1998-2001 (average of 9.3 cases per each month). The highest rate of pneumonias by Mycoplasma Pneumoniae was in may wit…
Osteogenesi imperfetta e deficit di GH: descrizione di una rara associazione.
2008
Two strange cases of hypereosinophilia and child's relapsing angio-oedema.
2003
Trappole nella diagnosi di APLV in età pediatrica.
2011
DOUBLE BLIND PLACEBO CONTROLLED FOOD CHALLENGE USEFUL TO DISCONFIRM OVER ESTIMATED DIAGNOSIS OF CMPA IN CHILDREN
2010
Sicurezza dell’Infliximab in bambini con malattia infiammatoria cronica intestinale (IBD): Registro pediatrico italiano di terapia biologica per le I…
2008
Analysis of functionally relevant single nucleotide polymorphisms of TNF alfa and of IFN gamma in celiac disease
2004
Functional gastrointestinal disorders: Dynamic observation of pediatric cases
2015
Introduction: Functional gastrointestinal disorders (FGID) are a variable set of clinical cases characterized by recurrent/chronic symptoms not associated with an organic pathology. These disorders are classified using the Rome III criteria. Objective: The study wanted to evaluate the prevalence by gender and age of FGIDs in a pediatric population recruited on the basis of recurrent/chronic abdominal pain, and to follow up patients for six months by administering questionnaires aimed at verifying any changes in symptoms. We also evaluated the possible involvement of factors responsible for these changes. Results: 62 patients between 4 and 17 years of age (27 males and 35 females) were inclu…
Epidemiological and clinical features in immigrant children with celiac disease : an italian multicentre study
2004
Mycoplasma Pneumoniae e neuropatia periferica.
2008
Idatidosi polmonare in età pediatrica: descrizione di un caso.
2008
Rachitismo carenziale in bambini adottati dall’estero: un problema emergente
2006
Coeliac disease : to screen or not to screen the general population ?
2005
Infliximab indispensabile per la remissione clinica nella malattia di Crohn refrattaria alla terapia tradizionale.
2005
Increased percentages of calprotectin and TNF-Α double-positive monocytes in the acute phase of Kawasaki disease
2011
Background The acute phase of KD is characterized by a deficiency of suppressor T cells, marked activation of the immune system and increased secretion of cytokines by immune effector cells. Moreover, it has been shown that myeloid-related protein (MRP-8 and MRP-14) and S100proteins, the major calcium-binding proteins secreted by activated neutrophils and monocytes, contribute to cause inflammation in acute lesions of KD, and indeed one of the more common hematological alteration in KD is the increase of peripheral blood monocytes. Calprotectin, one of the major calcium-binding proteins, can lead to direct and indirect effects that result not only in inflammation but also in modification of…
ASSOCIATION BETWEEN CELIAC DISEASE AND ENDOCRINE AUTOIMMUNE PATHOLOGIES
2013
Efficacia di FK506 per uso topico e Infliximab nel trattamento del coinvolgimento cutaneo nelle malattie infiammatorie croniche intestinali.
2010
Echinococcosi polmonare: un caso clinico
2008
Epidemiological trends of pediatric IBD in Italy: A 10-year analysis of the Italian society of pediatric gastroenterology, hepatology and nutrition r…
2022
Introduction: The present study aimed at evaluating Italian epidemiological trends of pediatric inflammatory bowel diseases (IBD) over the period 2009–2018. Materials and methods: Data from 1969 patients enrolled in the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition Registry, by 49 pediatric IBD centers throughout the country, were analyzed, comparing three different time intervals (2009–2012, 2013–2015, 2016–2018). Results: The number of new IBD diagnoses ranged from 175 to 219 per year, evenly distributed over the examined period of time. From 2009 to 2018, the minimal incidence ranged from 1.59 to 2.04 /105 inhabitants aged < 18 years, with an overall slight p…
Analysis of Candidate Genes in Celiac Disease: A Tool to Identify Life-Threatening Associated Genes?
2006
The authors have recently reported that celiac patients show a proinflammatory cytokine genetic profile characterized by the contemporaneous presence of both the tumour necrosis factor-alpha-308A and the interferon-gamma +874T allele-positive genotypes. The same alleles are considered risk factors for aging associated disease, whereas an anti-inflammatory cytokine genotype profile might be associated with an extended life expectancy. This paper reports data on the 1249-1250InsACAA/Non-Ins transforming growth factor (TGF)-beta2, a multifunctional anti-inflammatory cytokine, polymorphism distribution in 88 celiac disease (CD) patients, 99 age- and sex-matched controls, and 2895-year-old healt…
Malattia di Kawasaki: modalità di esordio e decorso clinico
2007
IBD does not always travel alone.
2007
Lo scorbuto in età pediatrica: descrizione di due casi recenti
2008
Association between previously identified disease loci at Chr 21q22 and MHC and UC in Italian population.
2009
Genotype / Phenotype analysis of a panel of genes in pediatric patients with IBD. A SIGENP multicentre study.
2006
Quando la MICI va dal reumatologo
2006
Familial Protein Losing Enteropathy
2006
Epstein-Barr virus-associated acute pancreatitis: a clinical report and review of literature.
2022
Abstract Background Acute pancreatitis is a disorder of reversible inflammation of the pancreas. Only a few cases are related to infections and the most common pathogens are the viruses responsible for mumps, parotitis, and influenza. Epstein-Barr virus (EBV)-associated acute pancreatitis is a rare condition and it may occur in children and adults. Case presentation A 3-year-old female was admitted to the “G. Di Cristina” Children's Hospital in Palermo for vomiting and abdominal pain. Laboratory investigations revealed elevated amylase and lipase, with normal liver function tests. Abdominal ultrasound demonstrated an enlarged pancreas, with hypoechogenic areas; no biliary lithiasis was obse…
UN CASO INUSUALE DI ANEMIA EMOLITICA
2007
AIG: Quanto si paga il ritardo diagnostico
2009
Effetti dell'allattamento al seno e dell'epoca di introduzione del glutine sullo sviluppo della malattia celiaca
2010
SCLERODEMIA SISTEMICA: DESCRIZIONE DI UN CASO IN ETA’ PEDIATRICA
2007
Associazione tra i geni identificati sul cromosoma 21q22 ed MHC e la RCU nella popolazione italiana adulta e pediatrica.
2009
Infliximab and topical tacrolimus administration effective in the treatment of Pyoderma Gangrenosum.
2009
Tricotiodistrofia
2005
855 Double Blind Placebo Controlled Food Challenge Useful to Disconfirm Over Estimated Diagnosis of Cmpa in Children
2010
Background and aims: The incidence of CMPA in infancy seems to be approximately 3%. In Italy diagnosis of CMPA is often over estimated. The double-blind, placebo controlled food challenge(DBPCFC) is widely considered as the “gold standard” for the diagnosis of food allergy. Methods: 14 patients, (12 months-12 yrs) previously diagnosed as having CMPA, underwent our diagnostic algorithm in order to confirm or to exclude diagnosis. Diagnostic algorithm includes: total blood cell count, serum IgE assay, RAST, betalactotest, Prick by prick with fresh milk, chemical examination and eosinophilic cell count of the stools. DBPCFC was performed with extensively hydrolyzed formula (as placebo) VS a la…