0000000001268403
AUTHOR
Kibrom Berihu Girum
Deep Generative Model-Driven Multimodal Prostate Segmentation in Radiotherapy
Deep learning has shown unprecedented success in a variety of applications, such as computer vision and medical image analysis. However, there is still potential to improve segmentation in multimodal images by embedding prior knowledge via learning-based shape modeling and registration to learn the modality invariant anatomical structure of organs. For example, in radiotherapy automatic prostate segmentation is essential in prostate cancer diagnosis, therapy, and post-therapy assessment from T2-weighted MR or CT images. In this paper, we present a fully automatic deep generative model-driven multimodal prostate segmentation method using convolutional neural network (DGMNet). The novelty of …
Automatic Myocardial Infarction Evaluation from Delayed-Enhancement Cardiac MRI using Deep Convolutional Networks
In this paper, we propose a new deep learning framework for an automatic myocardial infarction evaluation from clinical information and delayed enhancement-MRI (DE-MRI). The proposed framework addresses two tasks. The first task is automatic detection of myocardial contours, the infarcted area, the no-reflow area, and the left ventricular cavity from a short-axis DE-MRI series. It employs two segmentation neural networks. The first network is used to segment the anatomical structures such as the myocardium and left ventricular cavity. The second network is used to segment the pathological areas such as myocardial infarction, myocardial no-reflow, and normal myocardial region. The segmented …
3D landmark detection for augmented reality based otologic procedures
International audience; Ear consists of the smallest bones in the human body and does not contain significant amount of distinct landmark points that may be used to register a preoperative CT-scan with the surgical video in an augmented reality framework. Learning based algorithms may be used to help the surgeons to identify landmark points. This paper presents a convolutional neural network approach to landmark detection in preoperative ear CT images and then discusses an augmented reality system that can be used to visualize the cochlear axis on an otologic surgical video.
Learning With Context Feedback Loop for Robust Medical Image Segmentation
Deep learning has successfully been leveraged for medical image segmentation. It employs convolutional neural networks (CNN) to learn distinctive image features from a defined pixel-wise objective function. However, this approach can lead to less output pixel interdependence producing incomplete and unrealistic segmentation results. In this paper, we present a fully automatic deep learning method for robust medical image segmentation by formulating the segmentation problem as a recurrent framework using two systems. The first one is a forward system of an encoder-decoder CNN that predicts the segmentation result from the input image. The predicted probabilistic output of the forward system …
Stereo calibration of non-overlapping field of view heterogeneous cameras for calibrating surgicalmicroscope with external tracking camera
International audience
Use of Super Paramagnetic Iron Oxide Nanoparticles as Drug Carriers in Brain and Ear: State of the Art and Challenges
International audience; Drug delivery and distribution in the central nervous system (CNS) and the inner ear represent a challenge for the medical and scientific world, especially because of the blood–brain and the blood–perilymph barriers. Solutions are being studied to circumvent or to facilitate drug diffusion across these structures. Using superparamagnetic iron oxide nanoparticles (SPIONs), which can be coated to change their properties and ensure biocompatibility, represents a promising tool as a drug carrier. They can act as nanocarriers and can be driven with precision by magnetic forces. The aim of this study was to systematically review the use of SPIONs in the CNS and the inner e…
Automatic Myocardial Infarction Evaluation from Delayed-Enhancement Cardiac MRI Using Deep Convolutional Networks
In this paper, we propose a new deep learning framework for an automatic myocardial infarction evaluation from clinical information and delayed enhancement-MRI (DE-MRI). The proposed framework addresses two tasks. The first task is automatic detection of myocardial contours, the infarcted area, the no-reflow area, and the left ventricular cavity from a short-axis DE-MRI series. It employs two segmentation neural networks. The first network is used to segment the anatomical structures such as the myocardium and left ventricular cavity. The second network is used to segment the pathological areas such as myocardial infarction, myocardial no-reflow, and normal myocardial region. The segmented …
Inferring postimplant dose distribution of salvage permanent prostate implant (PPI) after primary PPI on CT images
International audience; PURPOSE:To evaluate the dose distribution of additional radioactive seeds implanted during salvage permanent prostate implant (sPPI) after a primary permanent prostate implant (pPPI).METHODS AND MATERIALS:Patients with localized prostate cancer were primarily implanted with iodine-125 seeds and had a dosimetric assessment based on day 30 postimplant CT (CT1). After an average of 6 years, these patients underwent sPPI followed by the same CT-based evaluation of dosimetry (CT2). Radioactive seeds on each CT were detected. The detected primary seeds on CT1 and CT2 were registered and then removed from CT2 referred as a modified CT2 (mCT2). Dosimetry evaluations (D90 and…
Real-Time Augmented Reality for Ear Surgery
International audience; Transtympanic procedures aim at accessing the middle ear structures through a puncture in the tympanic membrane. They require visualization of middle ear structures behind the eardrum. Up to now, this is provided by an oto endoscope. This work focused on implementing a real-time augmented reality based system for robotic-assisted transtympanic surgery. A preoperative computed tomography scan is combined with the surgical video of the tympanic membrane in order to visualize the ossciles and labyrinthine windows which are concealed behind the opaque tympanic membrane. The study was conducted on 5 artificial and 4 cadaveric temporal bones. Initially, a homography framew…
Artificial intelligence for image-guided prostate brachytherapy procedures
Radiotherapy procedures aim at exposing cancer cells to ionizing radiation. Permanently implanting radioactive sources near to the cancer cells is a typical technique to cure early-stage prostate cancer. It involves image acquisition of the patient, delineating the target volumes and organs at risk on different medical images, treatment planning, image-guided radioactive seed delivery, and post-implant evaluation. Artificial intelligence-based medical image analysis can benefit radiotherapy procedures. It can help to facilitate and improve the efficiency of the procedures by automatically segmenting target organs and extrapolating clinically relevant information. However, manual delineation…