0000000001303537

AUTHOR

E. Jijy

showing 11 related works from this author

Palladium-Catalyzed Skeletal Rearrangement of Spirotricyclic Olefins: A Facile One-Pot Strategy for the Synthesis of a Novel Motif with Cyclopentene …

2013

The first utilization of acyclic cyclopropane bearing spirocyclic olefines for the generation of stereospecific complex fused ring systems with an achiral catalyst is reported.

StereochemistryOrganic Chemistrychemistry.chemical_elementGeneral ChemistryCatalysisCoupling reactionCatalysisCyclopropanePyrazolidinechemistry.chemical_compoundStereospecificitychemistryCyclopenteneBenzofuranta116PalladiumChemistry - A European Journal
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An easy access to fused chromanones via rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins

2016

Abstract Herein we describe a detailed study on the rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins such as diazabicyclic olefins and urea-derived bicyclic olefins. The developed method provides an ideal route to fused chromanone systems in a single synthetic step. Moreover, the scope of this methodology was extended to different oxa/aza-bridged bicyclic urea derivatives.

diazabicyclic olefinsBicyclic moleculechromanone010405 organic chemistryOrganic Chemistrychemistry.chemical_elementrhodium catalyzedsalicylaldehyde010402 general chemistry01 natural sciencesBiochemistry0104 chemical sciencesRhodiumCatalysischemistry.chemical_compoundchemistrySalicylaldehydeDrug DiscoveryOrganic chemistryOxidative coupling of methaneUrea derivativesta116urea derived bicyclic olefinsTetrahedron
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Rhodium catalyzed oxidative coupling of salicylaldehydes with diazabicyclic olefins: a one pot strategy involving aldehyde C–H cleavage and π-allyl c…

2013

An efficient one pot strategy for the synthesis of cyclopentene fused chromanone derivatives through the direct oxidative coupling of salicylaldehydes with bicyclic olefins in the presence of a rhodium-copper catalyst system is described. This is the first report on the ring opening-ring closing of bicyclic hydrazines via metal catalyzed oxidative coupling reaction.

chemistry.chemical_elementAlkenesRing (chemistry)Medicinal chemistryAldehydeCatalysisCatalysisRhodiumchemistry.chemical_compoundMaterials ChemistryOrganic chemistryMoleculeCyclopenteneRhodiumta116chemistry.chemical_classificationAldehydesAza CompoundsMolecular StructureOxidative CouplingBicyclic moleculeMetals and AlloysGeneral ChemistrySurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryChromonesCyclizationCeramics and CompositesOxidative coupling of methaneChemical Communications
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ChemInform Abstract: Rhodium(III)-Catalyzed Ring-Opening of Strained Olefins Through C-H Activation of O-Acetyl Ketoximes: An Efficient Synthesis of …

2014

An efficient strategy for the stereoselective synthesis of functionalized cyclopentenes and spiro[2.4]heptenes from strained olefins via C–H activation of aryl ketone O-acetyl ketoximes using [RhCl2Cp∗]2 catalyst is described. The results revealed that a wide range of readily accessible aryl and heteroaryl ketoximes are compatible in this method for the ring opening of bicyclic and spirotricyclic olefins.

chemistry.chemical_compoundchemistryBicyclic moleculeArylchemistry.chemical_elementOrganic chemistryStereoselectivityGeneral MedicineAryl ketoneRing (chemistry)Medicinal chemistryRhodiumCatalysisChemInform
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ChemInform Abstract: Palladium-Catalyzed Skeletal Rearrangement of Spirotricyclic Olefins: A Facile One-Pot Strategy for the Synthesis of a Novel Mot…

2013

The first utilization of acyclic cyclopropane bearing spirocyclic olefines for the generation of stereospecific complex fused ring systems with an achiral catalyst is reported.

Pyrazolidinechemistry.chemical_compoundStereospecificityChemistryCyclopentenechemistry.chemical_elementGeneral MedicineBenzofuranRing (chemistry)Combinatorial chemistryCatalysisPalladiumCyclopropaneChemInform
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Rhodium(III)-catalyzed ring-opening of strained olefins through C–H activation of O-acetyl ketoximes: an efficient synthesis of trans-functionalized …

2013

An efficient strategy for the stereoselective synthesis of functionalized cyclopentenes and spiro[2.4]heptenes from strained olefins via C–H activation of aryl ketone O-acetyl ketoximes using [RhCl2Cp∗]2 catalyst is described. The results revealed that a wide range of readily accessible aryl and heteroaryl ketoximes are compatible in this method for the ring opening of bicyclic and spirotricyclic olefins.

Bicyclic moleculeChemistryArylOrganic Chemistrychemistry.chemical_elementAryl ketoneRing (chemistry)BiochemistryMedicinal chemistryRhodiumCatalysischemistry.chemical_compoundDrug DiscoveryCyclopenteneStereoselectivityta116Tetrahedron Letters
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ChemInform Abstract: Rhodium Catalyzed Oxidative Coupling of Salicylaldehydes with Diazabicyclic Olefins: A One-Pot Strategy Involving Aldehyde C-H C…

2013

The title reaction involves the first example of ring opening and ring closing of bicyclic hydrazines (I) via metal catalyzed oxidative coupling reaction.

chemistry.chemical_classificationBicyclic moleculechemistry.chemical_elementGeneral MedicineRing (chemistry)Cleavage (embryo)Medicinal chemistryAldehydeRhodiumCatalysisMetalchemistryvisual_artvisual_art.visual_art_mediumOxidative coupling of methaneChemInform
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ChemInform Abstract: An Easy Access to Fused Chromanones via Rhodium Catalyzed Oxidative Coupling of Salicylaldehydes with Heterobicyclic Olefins.

2016

Diazabicyclic and urea-derived bicyclic olefins react with salicylaldehydes to produce various types of fused chromanone systems of biological interest in a single step (mechanism).

Bicyclic moleculeChemistrychemistry.chemical_elementOxidative coupling of methaneSingle stepGeneral MedicineCombinatorial chemistryCatalysisRhodiumChemInform
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An easy access to fused chromanones via rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins

2016

Herein we describe a detailed study on the rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins such as diazabicyclic olefins and urea-derived bicyclic olefins. The developed method provides an ideal route to fused chromanone systems in a single synthetic step. Moreover, the scope of this methodology was extended to different oxa/aza-bridged bicyclic urea derivatives. peerReviewed

diazabicyclic olefinschromanonerhodium catalyzedsalicylaldehydeurea derived bicyclic olefins
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CCDC 952087: Experimental Crystal Structure Determination

2014

Related Article: E. Jijy, Praveen Prakash, M. Shimi, S. Saranya, P. Preethanuj, Petri M. Pihko, Sunil Varughese, K.V. Radhakrishnan|2013|Tetrahedron Lett.|54|7127|doi:10.1016/j.tetlet.2013.10.089

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersDiisopropyl 1-(5-(2-(N-hydroxyethanimidoyl)phenyl)spiro[2.4]hept-6-en-4-yl)hydrazine-12-dicarboxylateExperimental 3D Coordinates
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CCDC 1449575: Experimental Crystal Structure Determination

2016

Related Article: Ajesh Vijayan, T.V. Baiju, E. Jijy, Praveen Prakash, M. Shimi, Nayana Joseph, Petri M. Pihko, Sunil Varughese, K.V. Radhakrishnan|2016|Tetrahedron|72|4007|doi:10.1016/j.tet.2016.05.031

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterst-butyl 1315-bis(benzyloxy)-1014-dioxo-3-oxa-131516-triazatetracyclo[10.3.1.0211.049]hexadeca-468-triene-16-carboxylateExperimental 3D Coordinates
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