risultati dello studio pilota del progetto spin uti: un modello per la valutazione ed il monitoraggio dei programmi in sanità pubblica

RISULTATI PRELIMINARI DELLA SORVEGLIANZA AMBIENTALE DURANTE I LAVORI DI CANTIERE NELL'AOUP P. GIACCONE DI PALERMO

Linee guida per il controllo delle infezioni in odontoiatria

Rischio biologico e prevenzione delle infezioni occupazionali

Outbreak of ST395 KPC-Producing Klebsiella pneumoniae in a Neonatal Intensive Care Unit in Palermo, Italy

Indagine sulla presenza di anticorpi "R.conori" (reazione di microimmunofluorescenza) in sieri di soggetti sani nella sicilia occidentale

VACCINATION AND IMMUNIZATION STATUS AGAINST VACCINE-PREVENTABLE DISEASES IN AN ITALIAN SAMPLE OF HEALTH-CARE WORKERS OPERATING IN GYNAECOLOGY AND OBSTETRICS HOSPITAL DEPARTMENTS

Healthcare workers (HCWs) are an important group of professionals exposed to infectious diseases transmitted through several ways. Nevertheless, vaccination coverages of HCWs are often lower than standards recommended by international Public Health authorities. Recently, the Italian Ministry of Health has issued the guidelines for recommended vaccination during pregnancy, child-bearing age and feeding-time. This study aimed at investigating knowledge, attitudes, practices and immunization status in a sample of Italian HCWs employed in gynaecology and obstetrics departments. A survey was conducted between November 2017 and February 2018 throughout an online self-administered questionnaire, p…

Health effects of mercury ingested through consumption of seafood

It is known world-wide literature that seafood consumption is the main source of mercury intake in people not occupationally exposed. Several studies on the presence of mercury in sea water, sediment and fish and its effects on human health have been carried out in many countries in the Mediterranean area such as Greece, Italy and Jugoslavia. Few data have been published on Sicilian coastal population, consumers of high amounts of fish and on seawater status as the starting point of alimentary chains involving marine food. This study was carried out in July 1991 and July 1992 to determine total mercury and methylmercury levels in selected populations of the coast of Sicily: fishermen in a l…

Rischio biologico nei laboratori di microbiologia: epidemiologia e prevenzione

Effetti delle campagne di vaccinazione attiva contro l'influenza tra il personale dell'Azienda Ospedaliera Universitaria Policlinico

Man-made garbage pollution on the Mediterranean coastline

Abstract Measurements of persistent litter on 13 beaches in Spain, Italy (Sicily), Turkey, Cyprus and Israel between 1988 and 1989 show that plastic items are the most abundant in the litter composition, followed by wood, metal and glass items. Remnants of fishing gear are rather rare. It appears that the quantity of litter on a beach is inversely related to its geographical distance to a population center and directly related to the number of visitors frequenting it. Seasonal fluctuations in coastal litter are caused by storm waves which wash the litter landward, leaving the beach clean during winter, and by bathers who pollute it during summer. Based on the nature of the garbage, there ar…

Pregnancy and internet: sociodemographic and geographic differences in e-health practice. Results from an Italian multicenter study

Since the new millennium, the number of e-health users has significantly increased. Among these, a particular category of people who are interested by this phenomenon is the one of pregnant women. The aim of the present study is to assess the sociodemographic and geographic differences existing in a sample of Italian pregnant women who search for information on the web.Multicenter cross-sectional survey.The present study has been conducted from November 2011 to September 2012, in seven Italian cities, located in the North, in the Centre and in the South of Italy. Data were collected through an anonymous questionnaire, administered in waiting rooms of outpatient departments by trained medica…

The effects of dexametasone on the synthesis of protein, DNA, RNA, and hyaluronic acid in human synovial cells in culture

Valutazione della qualità della Sala Operatoria in funzione della prevenzione del rischio [Evaluation of operating theatre for the risk prevention]

In this study we analyse factors that predispose to risk and we value the importance of quality and reliability into operating theatre. Patient safety result from ability to plan and manage organizations able to reduce probability of mistakes (Prevention) and to recover and contain their consequences (Protection). The principal motives of mistakes are: - deficiency of sharing procedures between different professional figures for risk prevention; - deficiency of an effective integration between professional figures in operating theatre; - deficiency of charitable precise run to guarantee the continuity of interventions on patient. A risk management program have to take care on this sentinel …

La fissazione del complemento nella diagnosi di febbre esantematica del Mediterraneo

IL RISCHIO INFETTIVO NEL RIUNITO ODONTOIATRICO

UTILIZZO DI INTERNET IN GRAVIDANZA: RISULTATI PRELIMINARI DI UN’INDAGINE MULTICENTRICA SU UN CAMPIONE DI GESTANTI

Osservazioni sulla prevalenza e incidenza delle infezioni ospedaliere nel Policlinico Universitario di Palermo

Influenza vaccination among healthcare workers and absenteeism from work due to influenza-like illness in a teaching hospital in Palermo

<p><strong>Background</strong>: Annual flu vaccination of healthcare workers (HCWs) is recommended worldwide as the best way to prevent influenza and to avoid its transmission. However, in several European Countries, vaccination rate among HCWs is still less than 25%. The aim of this study was to determine the HCW vaccination coverage during a three year period in a large University Hospital, identifying socio demographic and occupational variables involved in the decision to accept influenza vaccination. Moreover, for the 2007-2008 season, we also assessed the effectiveness of influenza vaccination in reducing influenza-related absenteeism.</p><p><strong&gt…

l'Igiene del paziente senz'acqua

igiene, paziente,acqua

Operational efficiency of a pilot plant for wastewater reuse

Reuse of wastewaters for non-potable uses needs a higher than normal reliability in treatment plant operation and management, in order to ensure higher safety margins for public health and environmental protection. After a two-years research project on a pilot plant designed for agricoltural reuse, all control parameters used for the plant operation have been examined, in order to obtain useful observations on efficiency of each of the treatment units, for best overall performance. It was concluded that this type of package plant was able to produce a high quality effluent under various conditions, providing a good confidence on the reliability of the system. Reuse of wastewaters for non-po…

Network SPIN-UTI: valutazione degli aspetti organizzativi ed operativi del ProgettoSPIN

CONTROLLO DI Contaminazione microbica AMBIENTALE NEGLI Ambulatori Odontoiatrici DELL'AOUP Paolo Giaccone di Palermo.

Sorveglianza delle ssi nel reparto di cardiochirurgia dell’a.o.u.p. di Palermo -

EPIDEMIOLOGICAL STUDIES ON POSSIBLE LONG-TERM EFFECTS OF EXTREMELY LOW FREQUENCIES ELECTRICAL AND MAGNETIC FIELDS

Stima delle richieste di risarcimento presso l'Azienda Ospedaliera Universitaria Policlinico (A.U.O.P.)"P.Giaccone " Palermo.

Vaccination against the 2009 pandemic influenza A (H1N1) among healthcare workers in the major teaching hospital of Sicily (Italy)

The aim of the study was to investigate factors involved in vaccination acceptance among healthcare workers (HCWs) and adverse reactions rates associated with pandemic influenza vaccination. The study was carried out in the major teaching hospital of Sicily from November 2009 to February 2010 on 2267 HCWs. A total of 407 (18%) HCWs were vaccinated against the 2009 pandemic influenza A (H1N1). A logistic regression analysis indicates an increased risk of non-vaccination against pandemic influenza in females (OR = 1.6; 95% CI = 1.3-2.1) compared to males, in nurses/technicians/administrative workers (OR = 1.7; 95% CI = 1.3-2.2) compared to doctors/biologists, and in HCWs who were non-vaccinat…

Risk of Bacillus cereus and Pseudomonas aeruginosa nosocomial infections in a Burns Centre: the microbiological monitoring of water supplies for a preventive strategy

This paper reports on an extensive epidemiological survey of the microbiological monitoring of the environment, staff, and patients in the Intensive Care Unit of the Palermo Bums Centre (Italy). The aim of the survey was to evaluate the presence and distribution of environmental sources of pathogens and opportunistic bacterial agents of nosocomial infection in immunocompromised hosts. Strains collected from air, tap water, and medical and nursing staff were compared with strains isolated from burn patients in order to study the potential transmission route of bacteria. The results showed environmental strains presenting a profile identical to that of the clinical strains, suggesting a link …

International Journal of Infections Diseases

SETIL: Italian multicentric epidemiological case–control study on risk factors for childhood leukaemia, non hodgkin lymphoma and neuroblastoma: study population and prevalence of risk factors in Italy

Background Aetiology of childhood leukaemia and childhood neoplasm is poorly understood. Information on the prevalence of risk factors in the childhood population is limited. SETIL is a population based case–control study on childhood leukaemia, conducted with two companion studies on non-Hodgkin Lymphoma (NHL) and neuroblastoma. The study relies on questionnaire interviews and 50 Hz magnetic field (ELF-MF) indoor measurements. This paper discusses the SETIL study design and includes descriptive information. Methods The study was carried out in 14 Italian regions (78.3% of Italian population aged 0–10). It included leukaemia, NHL and neuroblastoma cases incident in 0–10 year olds in 1998–20…

Valutazione del monitoraggio microbiologico ambientale nwei complessi operatori dell'AOUP "Paolo Giaccone"

TUBERCOLOSI: DUE POPOLAZIONI A CONFRONTO. ITALIANI E STRANIERI NELL’A.O.U.P. “P. GIACCONE” DI PALERMO

REAZIONI AVVERSE CORRELATE ALLA VACCINAZIONE CONTRO L'INFLUENZA PANDEMICA (H1N1) PRESSO L'AZIENDA OSPEDALIERA UNIVERSITARIA "P. GIACCONE" (A.O.U.P.) DI PALERMO

Contributo alla conoscenza della reazione di Roemer e Schilipkoeter

Italian multicentricepidemiological case control strudy on risk factors for childhood leukemia,non hodgkin limphoma and neuroblastoma:study population and prevalence of risk factors in Italy

Background Aetiology of childhood leukaemia and childhood neoplasm is poorly understood. Information on the prevalence of risk factors in the childhood population is limited. SETIL is a population based case/control study on childhood leukaemia, conducted with two companion studies on non-Hodgkin Lymphoma (NHL) and neuroblastoma. The study relies on questionnaire interviews and 50 Hz magnetic field (ELF-MF) indoor measurements. This paper discusses the SETIL study design and includes descriptive information. Methods The study was carried out in 14 Italian regions (78.3% of Italian population aged 0?10). It included leukaemia, NHL and neuroblastoma cases incident in 0?10 year olds in 1998-20…

EPIDEMIOLOGIA DELLA LEISHMANIOSI IN SICILIA: STIMA DEL BURDEN DI MALATTIA ATTRAVERSO L’ANALISI DEI FLUSSI SANITARI CORRENTI.

INTRODUZIONE: La Sicilia è notoriamente terra endemica per la leishmaniosi, ma mancano, allo stato attuale, dei sistemi di sorveglianza attiva che permettano di quantificare precisamente il carico di malattia attribuibile a questa patologia protozoaria. Obiettivo del presente lavoro è stato quello di analizzare i flussi sanitari correnti disponibili al fine di stimare l’impatto della leishmaniosi sulla popolazione siciliana residente. MATERIALI E METODI: Lo studio ha analizzato due fonti: a) tutte le notifiche in classe II di leishmaniosi effettuate tra gennaio 2010 e dicembre 2013; b) le schede di dimissione ospedaliera (SDO) riportanti i codici ICD9-CM 085.1, 085.2, 085.3, 085.4, 085.5 ed…

Una rete nazionale di sorveglianza prospettica delle infezioni nosocomiali (IN) nelle terapie intensive (SPIN-UTI): la formazione per la standardizzazione delle procedure di rilevazione dei dati

Il contributo dell'epidemiologia analitica alla conoscenza della patologia da esposizione alle radiofrequenze (RF) e microonde (MO)

effetti biologici e sanitari dei campi elettrici e magnetici a frequenze estremamente basse

Valutazione metodologica della contaminazione microbica dell’aria in sala operatoria: campionamento attivo e campionamento passivo

OBIETTIVI: Valutazione della qualità microbiologica dell’aria nelle sale operatorie dell’A.O.U.P. “P. Giaccone” di Palermo mediante metodi di campionamento attivo e passivo. MATERIALI: Nel secondo semestre del 2009 sono stati effettuati campionamenti di aria in 20 sale operatorie (10 a flusso laminare e 10 a flusso turbolento) sia in condizioni di attività sia in condizioni di riposo. I punti di prelievo per il campionamento attivo sono stati: 1) il centro stanza 2) il VCCC; per il campionamento passivo 1) centro stanza 2) fondo stanza. Sono stati monitorati i seguenti parametri: carica batterica totale (CBT), carica micetica totale (CMT), Staphilococcus aureus ed Indice Microbico Aria (IMA…

The effects of dexamethasone on human synovial fibroblast-like cells, from ostheoarthritic joints, in culture

The effect of Dexamethasone (DEX) on cell division and macromolecular synthesis was investigated in a line (Mc Coy cells, A 9) of synovial fibroblast-like cells derived from human osteoarthritic joints. DEX markedly reduced the proliferation of Mc Coy cells in a time and dose-dependent manner. The maxiamal inhibition (45 %) was found at 500 nM DEX 24 h after incubation and was accompanied by the appearance of giant macrophage-like cells. After DEX treatment cells showed increased content of DNA, proteins and RNA together with the reduction of [3H]-thymidine incorporation into the TCA-precipitable fraction.

La valutazione degli ospedali generali di 1° livello: il caso dell'ospedale " G Giglio di Cefalù"

Valutazione del rischio biologico negli operatori sanitari

SORVEGLIANZA ATTIVA PROSPETTICA DELLE INFEZIONI NOSOCOMIALI NELLE TERAPIE INTENSIVE: PROGETTO PER UNA RETE

Healthcare-associated infections over an eight year period in a large university hospital in Sicily (Italy, 2011–2018)

Background: Up to 7% of hospitalised patients acquire at least one healthcare-associated infection (HAI). The aim of the present study was to quantify the burden of HAIs in an Italian hospital, identifying involved risk factors. Methods: Prevalence point study carried out from 2011 to 2018. For each recruited patient, a data entry form was compiled including information on demographics, hospital admission, risk factors, antimicrobial treatment, and infection if present. Results: A total of 2844 patients were included and 218 (7.03%) reported an infection. HAI prevalence rates showed a significant increase (average annual per cent change (AAPC) +33.9%; p=0.018) from 2011 to 2014 whereas from…

La bilicultura un'utile guida per la terapia antibiotica nella chirurgia delle vie biliari

Road Traffic Pollution and Childhood Leukemia: A Nationwide Case-control Study in Italy

Background The association of childhood leukemia with traffic pollution was considered in a number of studies from 1989 onwards, with results not entirely consistent and little information regarding subtypes. Aim of the study We used the data of the Italian SETIL case-control on childhood leukemia to explore the risk by leukemia subtypes associated to exposure to vehicular traffic. Methods We included in the analyses 648 cases of childhood leukemia (565 Acute lymphoblastic–ALL and 80 Acute non lymphoblastic-AnLL) and 980 controls. Information on traffic exposure was collected from questionnaire interviews and from the geocoding of house addresses, for all periods of life of the children. Re…

main routes of trasmission of human immunodeficiency virus (HIV) infection in a family setting in Palermo: some biological properties of the new isolated.

Indagine multicentrica sull’igiene orale di studenti universitari

RISULTATI DI UNA INDAGINE EFFETTUATA PRESSO L'AOUP “PAOLO GIACCONE” DI PALERMO PER LA VALUTAZIONE DEI COMPLESSI OPERATORI

Il metodo colturale tradizionale e la bioluminiscenza per la valutazione della sanificazione delle superfici. Correlazione tra i risultati di un'indagine condotta nelle degenze dell'AOUP "P. Giaccone" di Palermo.

Uno studio di intevento per la prevenzione delle infezioni ospedaliere

Applicazione di nuove metodiche di tipizzazione allo studio di stipiti batterici responsabili di infezioni ospedaliere.

Sicurezza in sala operatoria: il recepimento delle Direttive Ministeriali in due strutture ospedaliere della Provincia di Palermo.

Introduzione La necessità di migliorare la qualità delle prestazioni ospedaliere ha sensibilizzato il Ministero della Salute all’elaborazione ed emanazione di Linee Guida sulle attività di sala operatoria per avere su tutto il territorio nazionale un documento unico e ufficialmente riconosciuto, adattabile alle esigenze locali. Obiettivi L’iter operatorio si compone di almeno tre grandi variabili: la complessità intrinseca caratterizzante tutte le procedure chirurgiche, la multidisciplinarietà delle figure professionali coinvolte e la componente organizzativo-strutturale. Si è confrontato il recepimento delle Linee Guida ministeriali in materia di sicurezza in sala operatoria in due realtà …

Infezioni correlate all'assistenza sanitaria

A computation study to evaluate indoor gamma dose-rate on the basis of outdoor measurements

Impiego di un substrato fluorogeno per una prova rapida di conferma della colimetria in acque di mare.

Health effects of mercurv ingested through consumption of seafood

Rischio Biologico e operatori sanitari: risultati di 10 mesi di sorveglianza sugli incidenti occupazionali dell'AOUP di Palermo

valutazione della conoscenza della metodologia della prevenzione in studenti di odontoiatria del vecchio e del nuovo ordinamento

Valutazione dei requisiti per l’accreditamento nell’azienda ospedaliera universitaria -

Indagine conoscitiva sui requisiti organizzativi-strutturali dei complessi operatori svolta presso l'AOUP "Paolo Giaccone" di Palermo

Tobacco smoke and risk of childhood acute non-lymphocytic leukemia: findings from the SETIL study.

Background Parental smoking and exposure of the mother or the child to environmental tobacco smoke (ETS) as risk factors for Acute non-Lymphocytic Leukemia (AnLL) were investigated. Methods Incident cases of childhood AnLL were enrolled in 14 Italian Regions during 1998–2001. We estimated odds ratios (OR) and 95% confidence intervals (95%CI) conducting logistic regression models including 82 cases of AnLL and 1,044 controls. Inverse probability weighting was applied adjusting for: age; sex; provenience; birth order; birth weight; breastfeeding; parental educational level age, birth year, and occupational exposure to benzene. Results Paternal smoke in the conception period was associated wit…

Main routes of trasmission of human immunodeficiency virus (HIV)infection in a family setting in Palermo, Italy.

A cross-sectional seroepidemiologic study was carried out on household contacts and sexual partners of human immunodeficiency virus (HIV) antibody-positive intravenous drug abusers in Palermo, Italy, in 1985 to evaluate factors that influenced HIV transmission. A total of 43 index cases, 36 spouses or heterosexual partners, 28 children, and 55 adult household members were enrolled. None of the household members without sexual contact, who had shared items and facilities and had interacted with the index cases, contracted HIV infection. However, six of 36 sexual partners had antibodies to HIV. It was observed that the risk of HIV infection was significantly associated with the frequency of s…

Efficacia della sorveglianza microbiologica e di un intervento tempestivo in una unita’ di terapia intensiva dell’A.O.U.P. di Palermo -

Studio di prevalenza europeo sulle infezioni correlate all'assistenza e sull'uso degli antibiotici negli ospedali per acuti

Impact of Candida species colonization and azoles resistance in a neonatal intensive care unit

Background: Candida species are among the top 10 most frequently isolated nosocomial bloodstream pathogens in Europe. In particular, in neonatal intensive care units (NICUs) Candida infections are an emerging concern because of the increasing incidence, the related high morbidity and mortality rates reported. Moreover, the epidemiology of Candida infection rapidly changed in these years leading to the selection of less sensitive strains and species. Surveillance studies are mandatory to identify the local distribution of species, their antifungal susceptibility profiles and the emergence of resistance strains. Material/methods: From December 2012 we performed a cohort prospective surveillan…

La vaccinazione antinfluenzale come Strumento di Sanità pubblica e di prevenzione. Esperienza dell'Azienda Ospedaliero Universitaria Policlinico (AOUP) "P. Giaccone "di Palermo. Analii

Condizioni igienico-sanitarie delle acque costiere della provincia di Palermo

Valutazione dell’adeguatezza dei comportamenti del personale nei complessi operatori dell’AOUP “P. Giaccone” di Palermo

Valutazione della qualità igienica del gruppo idrico nei riuniti della clinica odontoiatrica del Policlinico Universitario di Palermo

Uridine enhances the cytotoxic effect of D-glucosamine in rat C6 glioma cells.

This paper studies the influence of uridine on the effects exerted by D-glucosamine in rat C6 glioma cells. 2 mM uridine increased markedly both the cytotoxic effect of the aminosugar and the inhibition of thymidine incorporation into acid-insoluble fraction. Furthermore the complete resumption of the capacity to incorporate either 3H-thymidine or 3H-mannose which was observed after the removal of the aminosugar, was impeded when the cells were treated contemporaneously with D-glucosamine and uridine. An exposure for 4 hr to 20 mM glucosamine alone enhanced about 15-fold the cellular pool of UDP-N-acetylhexosamines; the addition of 2 mM uridine intensified the expansion of this pool, which …

Valutazione delle condizioni microclimatiche nelle sale di degenza e nelle terapie intensive.

Impianto di ventilazione e condizionamento a contaminazione controllata (VCCC),contaminazione microbica dell'aria e infezione del sito chirurgico in interventi di artroprotesi:il progetto ISChIA del GISIO-SITI

Coastal recreational water quality and human health

A survey of tubercolin reactivity in school children and Palermo University medícal school students

Predicting needlestick and sharps injuries in nursing students: Development of the SNNIP scale

© 2020 The Authors. Nursing Open published by John Wiley & Sons Ltd. Aim: To develop an instrument to investigate knowledge and predictive factors of needlestick and sharps injuries (NSIs) in nursing students during clinical placements. Design: Instrument development and cross-sectional study for psychometric testing. Methods: A self-administered instrument including demographic data, injury epidemiology and predictive factors of NSIs was developed between October 2018–January 2019. Content validity was assessed by a panel of experts. The instrument's factor structure and discriminant validity were explored using principal components analysis. The STROBE guidelines were followed. Results: E…

L'ospedale: realtà e futuro proponibile

In this work we run over hospital history from Middle ages to the present time. Hospitals were charitable institutions in fact they rise inside monasterys, churches or castles with an architecture in modum crucis as a symbolic expression of Christ crucifix. During Renaissance, new scientific Knowledges and the need of technical assistance in a suitable place, lead to a new kind of hospital included into the functional centres of the city were medical practice takes the places of spiritual assistance. In XVIII century hospital is like a "human diseases botanical garden" divided into departments with a circular structure in conformity with a functional model of control. To exceed the isolatio…

Correlation between staphylococcal skin infections and sea bathing: a case-control study.

building a benchmark througth active surveillance: the Italian Network SPIN-UTI

La vaccinazione antinfluenzale come Strumento di Sanità pubblica e di prevenzione. Esperienza dell'Azienda Ospedaliero Universitaria Policlinico (AOUP) "P. Giaccone "di Palermo. Analisi e confronto della copertura da vaccino negli anni 2005-2009.

Introduzione Le Linee guida per la prevenzione e controllo dell'influenza, emanano Ogni anno dal Ministero della Salute, raccomandano la vaccinazione per tutti Coloro Che svolgono Funzioni lavorative di primario interesse collettivo. Il personale sanitario rappresenta, un tal Riguardo, un obiettivo strategico della campagna da vaccino antinfluenzale SIA per la possibile trasmissione dell'influenza aviaria Pazienti SIA Perchè l'eventuale assenteismo Potrebbe inficiare la qualità e la Capacità dell'Assistenza erogata. La trasmissione dell'influenza ad un Paziente è sicuramente un importante Rischio nosocomiale in Quanto l'Infezione virale PUÒ portare ad un aggravamento dello stato di salute d…

Management of pandemic influenza A (H1N1)2009 in the major University Hospital of Sicily

La reazione di emoagglutinazione(TPHA) nella sierologia della sifilide

La contaminazione indoor da Legionella spp: risultati preliminari di una indagine multicentrica italiana Legionella spp contamination in indoor air: preliminary results of an italian multicenter study

Sorveglianza delle Infezioni Nosocomiali in una Unità di Cardiochirurgia di Palermo.

Valutazione del rischio infettivo occupazionale nell’A.O.U.P. di Palermo: dieci anni di sorveglianza

Nel presente lavoro sono stati esaminati gli eventi infortunistici occupazionali a rischio biologico avvenuti nell’Azienda Ospedaliera Universitaria Policlinico di Palermo nel decennio 2000-2011 al fine di rilevarne l’incidenza, anche in considerazione degli interventi di prevenzione adottati, le circostanze dell’evento, le categorie professionali maggiormente a rischio, le caratteristiche dell’operatore sanitario e, se noto, il quadro sierologico del paziente fonte. A tale scopo è stato esaminato un data-base dell’Azienda in cui vengono inseriti i suddetti dati al momento dell’incidente occupazionale a rischio infettivologico. Dall’elaborazione degli stessi è emerso che nell’anno 2000 l’in…

Risk of bacillus cereus and pseudomonas aeruginosa nosocomial infections in a burns centre: the microbiological monitoring of water supplies for a preventive strategy

Opportunist bacteria are a potentially very serious problem in hospital burns units, particularly where the quantity and quality of water supplies may not be reliable, and patients are especially vulnerable. A programme of routine microbiological monitoring is described which minimises the risk to patients.

MAIN ROUTES OF TRANSMISSION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION IN A FAMILY SETTING IN PALERMO, ITALY1

A cross-sectional seroepidemiologic study was carried out on household contacts and sexual partners of human immunodeficiency virus (HIV) antibody-positive intravenous drug abusers in Palermo, Italy, in 1985 to evaluate factors that influenced HIV transmission. A total of 43 index cases, 36 spouses or heterosexual partners, 28 children, and 55 adult household members were enrolled. None of the household members without sexual contact, who had shared items and facilities and had interacted with the index cases, contracted HIV infection. However, six of 36 sexual partners had antibodies to HIV. It was observed that the risk of HIV infection was significantly associated with the frequency of s…

AIDS in Sicily: prevalence of antibodies to human immunodeficiency virus (HIV) in low and high risck groups

Valutazione del rischio biologico negli operatori sanitari;infezioni correlate all'assistenza sanitaria (ICA)

A model of microbiological monitoring for prevention of H.A.I. in a Burns Centre.

Stima delle richieste di risarcimento presso l'Azienda Ospedaliera Universitaria Policlinico (A.O.U:P.) "P. Giaccone" di Palermo

Gestione di un evento epidemico in un reparto ad alto rischio

Aspergillosi invasiva nosocomiale e cantieri in opspedale

Il metodo colturale tradizionale per la valutazione della sanificazionme delle superfici. Correlazione tra i risultati di un'indagine condotta nelle degenze dell'A.U.O.P. "P.Giaccone"di Palermo

The Carini experimental station for wastewater reuse in agricolture.

attività del gruppo di lavoro di Igiene in odontoiatria

Prevention of hospital-acquired infection in the Palermo Burns Center.

Characterization ofBacillus thuringiensisisolated from infections in burn wounds

Four strains of Bacillus thuringiensis were isolated from infections in burn wounds and from water used in the treatment of burn wounds. The strains produced large parasporal inclusion bodies composed of 141, 83, and 81 kDa protoxins. The four strains were tested for insecticidal activity against larvae of Pieris brassicae and Aedes aegypti but showed no activity; Vero cell assays for the production of enterotoxins were also negative. Attempts to classify the strains according to flagellar H-serotype showed them all to be non-flagellated. Apart from two occupational health accidents that occurred during the handling of highly concentrated B. thuringiensis fluids, this is the first report of…

la prevenzione del rischio biologico negli operatori sanitari

Knowledge about tuberculosis among undergraduate health care students in 15 Italian universities: a cross-sectional study

Background: The Italian Study Group on Hospital Hygiene of the Italian Society of Hygiene, Preventive Medicine and Public Health conducted a multicentre survey aiming to evaluate undergraduate health care students’ knowledge of tuberculosis and tuberculosis control measures in Italy. Methods: In October 2012–June 2013, a sample of medical and nursing students from 15 Italian universities were enrolled on a voluntary basis and asked to complete an anonymous questionnaire investigating both general knowledge of tuberculosis (aetiology, clinical presentation, outcome, screening methods) and personal experiences and practices related to tuberculosis prevention. Data were analysed through multiv…

Bacterial and chemical indicator of coastal water pollution.

This study has been carried out to compare the presence of some organic compounds of long environmental persistance (OCLEP) and heavy metals, in sea water samples, with faecal pollution indicators. Along the Sicily coast line three sites with different grade of pollution (urban, agricultural, industrial) were sampled. 69 samples were obtained from October 1987 to May 1990. Only indicators of faecal pollution were found linked to human settlements, while the other investigated anthropogenic activity related substances were found independently from sampling area.

Microclima nei reparti di degenza - Dati preliminari

Il Management in sala operatoria: l'esperienza dell'A.O.U.P. "Paolo Giaccone" -palermo

Effects of dexamethasone on human synovial fibroblast-like cells, from osteoarthritic joints, in culture.

The effect of Dexamethasone (DEX) on cell division and macromolecular synthesis was investigated in a line (McCoy cells, A 9) of synovial fibroblast-like cells derived from human osteoarthritic joints. DEX markedly reduced the proliferation of McCoy cells in a time and dose-dependent manner. The maximal inhibition (45%) was found at 500 nM DEX 24 h after incubation and was accompanied by the appearance of giant macrophage-like cells. After DEX treatment cells showed increased content of DNA, proteins and RNA together with the reduction of [3H]-thymidine incorporation into the TCA-precipitable fraction.

Exposure to benzene and childhood leukaemia: a pilot case-control study

Objectives Main purpose To evaluate the feasibility of a measurement-based assessment of benzene exposure in case-control studies of paediatric cancer; Additional aims To identify the sources of exposure variability; to assess the performance of two benzene biomarkers; to verify the occurrence of participation bias; to check whether exposures to benzene and to 50 Hz magnetic fields were correlated, and might exert reciprocal confounding effects. Design Pilot case-control study of childhood leukaemia and exposure to benzene assessed by repeated seasonal weekly measurements in breathing zone air samples and outside the children9s dwellings, with concurrent determinations of cotinine, t-t-muco…

malattie Infettive: notifica dell'Azienda Ospedaliera Universitaria Policlinico di Palermo

Millimeter wave effects in Candida albicans cells

prestazioni erogate dal laboratorio centralizzati dell'AOUP "Paolo Giaccone" di Palermo

Control and prevention measures for legionellosis in hospitals: A cross-sectional survey in Italy

Abstract Risk assessment, environmental monitoring, and the disinfection of water systems are the key elements in preventing legionellosis risk. The Italian Study Group of Hospital Hygiene of the Italian Society of Hygiene, Preventive Medicine, and Public Health and the Italian Multidisciplinary Society for the Prevention of Health Care-Associated Infections carried out a national cross-sectional survey to investigate the measures taken to prevent and control legionellosis in Italian hospitals. A multiple-choice questionnaire was developed, comprising 71 questions regarding hospital location, general characteristics, clinical and environmental surveillance, and control and preventive measur…

Serological and molecular identification of Legionella spp. isolated from water and surrounding air samples in Italian healthcare facilities

Abstract Background Legionella is an intracellular microorganism living in natural and artificial aquatic environments. Although its transmission to humans is linked to the inhalation of contaminated aerosols, there is no validated air sampling method for the control and prevention of the disease. The aim of the present study was to provide more information on the distribution of Legionella spp. in indoor environments and to determine whether the same Legionella strains are isolated from air and water samples. Methods Ten healthcare facilities located in seven regions of Italy were enrolled. The serological typing of Legionella spp. from water samples and the surrounding air by active and p…

Vaccination against the 2009 pandemic influenza A (H1N1) among healthcare workers in the major teaching hospital of Sicily (Italy).

Aderenza alle linee guida sulla profilassi antibiotica delle infezioni della ferita chirurgica nel Policlinico Universitario "P. Giaccone" di Palermo

Indagine sul Rischio Biologico (RB) in un azienda ospedaliera: operatori sanitari e odontoiatri (gennaio 2000- maggio 2005)

Setil:Italian multicentric epidemiological study on risk factors for childhood leukemia, non Hodgkin lymphoma and neuroblastoma

Sicurezza nei luoghi di lavoro

Come predisporre un protocollo per la sorveglianza delle infezioni nei reparti per ustionati

An intercalibration study of the use of 4-Methyumbelliferyl-ß-D-glucuronide for the specific enumeration of Escherichia coli in seawater and marine sediments.

A fluorogenic assay for the specific detection of Escherichia coli on the basis of its β-glucuronidase activity (MUG method) was applied to seawater and marine sediments with different contamination levels. The study was carried out in three Mediterranean areas (Malaga-Spain, Nice-France and Palermo-Sicily), using strictly standardized methods (membrane filtration), media (mFC and Chapman-TTC agars) and reagents, to evaluate statistically its sensitivity and specificity according to the origin and contamination of samples, the workers performing the tests and the selected culture media. The results obtained indicate that the MUG method is highly specific (94.5%) and sensitive (90.8%) for th…

The Carini Experimental Station for Wastewater Reuse in Agriculture – Preliminary Indications

A two year experiment, to study the feasibility of wastewater reuse for a safe irrigation in the Sicilian context, has been initiated. Eight plots in two fields, totalling 629 m2, were planted with cowpeas (Vigna unguiculata L. Walp.), the irrigation water being supplied by a pilot plant treating 22 m3/day of municipal wastewater. The plant consists of an extended aeration biological system followed by rapid sand filtration and a choice of disinfection systems. Analyses performed on all waters used in the experiment indicate that safe irrigation water, virtually pathogen-free, can be produced if careful operational techniques are adopted. Despite all possible care, however, soil samples tak…

La gestione del rischio infettivo in un Policlinico Universitario

Sorveglianza delle Infezioni Nosocomiali nel reparto di Cardiochirurgia dell'AOUP di Palermo

microwave effects on isolated chick embrio heart

This study was designed to examine the effects of microwaves on the electric activity of hearts as a means of elucidating interactive mechanisms of nonionizing radiation with cardiac tissue. Experiments were performed on isolated hearts of 9-12-day-old chick embryos placed in small petri dishes. Oxygenated isotonic Ringer's solution at 37 degrees C permitted heart survival. Samples were irradiated at 2.45 GHz with a power density of 3 mW/cm2. The heart signal was detected with a glass micropipet inserted into the sinoatrial node and examined by means of a Berg-Fourier analyzer. Pulsed microwaves caused the locking of the heartbeat to the modulation frequency, whereas continuous wave irradia…

Riflessioni sulla didattica relativa all'insegnamento dell'Igiene Ospedaliera nei corsi di laurea delle professioni sanitarie

Management delle Sale Operatorie: esperienza condotta presso l'AOUP di Palermo

Ristorazione Ospedaliera : Indagine conoscitiva svolta presso le UU.OO. dell'AOUP "Paolo Giaccone" di Palermo

Gestione di un evento epidemico di scabbia nell'AUOP

Modified most-probable-number technique for the specific determination of Escherichia coli from environmental samples using a fluorogenic method

A specific and senstive modification of the most-probable-number (MPN) technique by addition of 4-methylumbelliferyl-β-D-glucuronide (MUG) to both presumptive and confirmatory media was performed. The use of this modification allows the precise determination of Escherichia coli from marine samples (seawater, sediment and shellfish) within 7 days compared to 10–12 days required by using of the standard methodology. No false-positive isolates for fluorescence reaction have been observed, although one E. coli strain fluorescent-positive on agar was isolated from nonfluorescent tubes. Klebsiella pneumoniae was the species most frequently detected from tubes with gas and fluorescence production …

linee guida per la sterilizzazione a vapore

linee guida per il lavaggio delle mani