6533b7d5fe1ef96bd12648b1

RESEARCH PRODUCT

Morphea after silicone gel breast implantation for cosmetic reasons in an HLA-B8,DR3-positive woman

G. Di LorenzoGiuseppina CandoreM. MellusoDiego CignaGiuseppe Barbagallo SangiorgiPasquale MansuetoCalogero Caruso

subject

Adultmusculoskeletal diseasesmedicine.medical_specialtyBreast implantationBreast ImplantsMammaplastyImmunologyMammary glandCD4-CD8 RatioSiliconesHLA-B8 AntigenScleroderma Localizedchemistry.chemical_compoundHLA-DR3 AntigenSiliconeLocalized morpheamedicineHumansImmunology and AllergySurgery Plasticskin and connective tissue diseasesGlucocorticoidsbusiness.industrytechnology industry and agricultureGeneral Medicinemedicine.diseaseConnective tissue diseaseSurgeryPlastic surgerymedicine.anatomical_structurechemistryImmunologyPrednisoneFemalebusinessMorpheaCircumscribed scleroderma

description

We describe an HLA-B8, DR3-positive patient with localized morphea after silicone gel breast implantation for cosmetic reasons. We believe that this case suggests that a genetic background, i.e. HLA-B8, DR3 haplotype, is involved in the autoimmune response to silicone.

yearjournalcountryeditionlanguage
1997-01-01
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031060697&partnerID=MN8TOARS