6533b7d6fe1ef96bd12665c0
RESEARCH PRODUCT
Use of neural networks for dosage individualisation of erythropoietin in patients with secondary anemia to chronic renal failure.
Gustavo Camps VallsAntonio LópezJosé David Martín GuerreroJuan José Pérez RuixoEmilio Soria OlivasN. Víctor Jiménez Torressubject
medicine.medical_specialtymedicine.diagnostic_testAnemiaSecondary anemiabusiness.industrymedicine.medical_treatmentHealth InformaticsAnemiamedicine.diseaseRecombinant ProteinsComputer Science ApplicationsTherapeutic drug monitoringErythropoietinmedicineQuality of LifeChronic renal failureHumansKidney Failure ChronicIn patientHemodialysisNeural Networks ComputerIntensive care medicinebusinessErythropoietinmedicine.drugdescription
The external administration of recombinant human erythropoietin is the chosen treatment for those patients with secondary anemia due to chronic renal failure undergoing periodic hemodialysis. The goal is to carry out an individualised prediction of the erythropoietin dosage to be administered. It is justified because of the high cost of this medication, its secondary effects and the phenomenon of potential resistance which some individuals suffer. One hundred and ten patients were included in this study and several factors were collected in order to develop the neural models. Since the results obtained were excellent, an easy-to-use decision-aid computer application was implemented.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-07-01 | Computers in biology and medicine |