6533b7d6fe1ef96bd1266bf0

RESEARCH PRODUCT

PADDIAG: Plasmon-Acoustic Device for in vitro Diagnosis

Rabah ZeggariJean-françois ManceauReda YahiaouiEric LesniewskaWilfrid Boireau

subject

[SPI.NANO] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics

description

The aim of the project is to develop a plasmon-acoustic device for the real time detection of biomolecular interactions, in the prospect of cancer markers detection in blood samples from patients. In the context of early diagnosis, the detection of infinitesimal quantities of biomarkers is possible thanks to the breakdown of the equilibrium state of biochemical reactions. This could be obtained by the activation of the biological media using a system composed of a microdevice for generating acoustic waves coupled with a fluidic network. The latter system will be integrated on a detection device based on surface plasmon resonance. Here, we present design, realization and characterization of the acoustic activation device fabricated on silicon thanks to technological facilities of MIMENTO and ARCEN platforms

https://hal.science/hal-00967043