6533b7d8fe1ef96bd126a4a1

RESEARCH PRODUCT

Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum

Bart P. F. RuttenBart P. F. RuttenJulio SanjuánJ. Van OsJ. Van OsJ. Van OsS. Andric PetrovicAlp ÜçOkJulio BobesN. MaricSilvia AmorettiP.a. SáizMichael Conlon O'donovanGonzalo LópezJair Lício Ferreira SantosGisela MezquidaKöksal AlptekinKöksal AlptekinHalis UlaşBerna YalınçetinE. ŞAhin CankurtaranPhilippe DelespaulJurjen J. LuykxJurjen J. LuykxManuel ArrojoMiguel BernardoLotta-katrin PriesM. Paz García-portillaJavier González-peñasGunter KenisCelso ArangoTolga BinbayTijana MirjanicAlexander RichardsBurçin CihanM. ParelladaHaldun SoygürM. Can SakaBochao LinS. Ulusoy KaymakCem AtbaşoğluVesile AltınyazarAngel CarracedoBerna Binnur AkdedeGüvem Gümüş-akayMarina MihaljevicEstela Jiménez-lópezGenetic RiskG. A. Dal FerroS. TosatoSinan GuloksuzEduardo J. Aguilar

subject

AdultMaleExposomePsychosisMultifactorial InheritanceEpidemiologyBIRTHSchizotypystructured interviewGENE-ENVIRONMENTPopulationschizotypypopulationEnvironment03 medical and health sciences0302 clinical medicineMedicineHumansSpectrum disorderGenetic Predisposition to DiseasegeneticspsychosiseducationMETAANALYSISvalidationRISKeducation.field_of_studychildhood traumareliabilitybusiness.industryPublic Health Environmental and Occupational HealthAbsolute risk reductionassociationRegression analysisGenomicsmedicine.disease3. Good health030227 psychiatryPsychiatry and Mental healthPsychotic DisordersSchizophreniaSchizophreniaFemaleGene-Environment InteractionSchizophrenic PsychologyOriginal Articlebusiness030217 neurology & neurosurgeryClinical psychology

description

The EUGEI project was supported by the European Community’s Seventh Framework Program under grant agreement no. HEALTH-F2-2009-241909 (Project EU-GEI). Dr O’Donovan is supported by MRC programme grant (G08005009) and an MRC Centre grant (MR/ L010305/1). Dr Rutten was funded by a VIDI award number 91718336 from the Netherlands Scientific Organisation. Drs Guloksuz and van Os are supported by the Ophelia research project, ZonMw grant number: 636340001. Dr Arango was supported by the Spanish Ministry of Science and Innovation; Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/024); CIBERSAM; Madrid Regional Government (B2017/BMD-3740, AGES-CM-2); Fundación Familia Alonso and Fundación Alicia Koplowitz.

yearjournalcountryeditionlanguage
2020-11-17Epidemiology and Psychiatric Sciences
10.1017/s2045796020000943https://doi.org/10.1017/S2045796020000943