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RESEARCH PRODUCT
Echocardiographic reference ranges for normal cardiac chamber size: Results from the NORRE study
Daniele BaroneMonica BaroniNico Van De VeireKrasimira HristovaSeisyou KouChristine HenriDamien VoilliotGeorge KacharavaJulien MagneLuigi P. BadanoJosé Juan Gómez De DiegoRalph Stephan Von BardelebenDragos VinereanuAlessandro SalustriMartin PenickaJens-uwe VoigtAndreas HagendorffJose David Rodrigo CarboneroRoberto M. LangCarla De SousaBogdan A. PopescuGeorge AthanassopoulosPatrizio LancellottiTolga OzyigitTeresa LópezErwan DonalNuno CardimGonzalo De La MorenaJosé Luis ZamoranoRaluca Elena DulgheruLuis Caballerosubject
MaleLower blood pressureSex FactorHeart VentricleCohort StudiesChamber size and function; Reference values; Two-dimensional echocardiography; Cardiology and Cardiovascular Medicine; Radiology Nuclear Medicine and Imaging; Medicine (all)Nuclear Medicine and ImagingAge FactorReference ValueYoung adultBody surface areaObserver VariationMedicine (all)Age FactorsGeneral MedicineStroke volumeMiddle AgedEchocardiographyCardiologyFemaleCardiology and Cardiovascular MedicineRadiologyHumanCohort studyAdultmedicine.medical_specialtyHeart VentriclesReproducibility of ResultChamber size and functionRisk AssessmentReference valuesYoung AdultSex FactorsTwo-dimensional echocardiographyInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingHeart AtriaAgedbusiness.industryReproducibility of ResultsMean ageStroke VolumeMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREOriginal ArticlesCardiac chamberReference valuesCohort Studiebusinessdescription
AimsAvailability of normative reference values for cardiac chamber quantitation is a prerequisite for accurate clinical application of echocardiography. In this study, we report normal reference ranges for cardiac chambers size obtained in a large group of healthy volunteers accounting for gender and age. Echocardiographic data were acquired using state-of-the-art cardiac ultrasound equipment following chamber quantitation protocols approved by the European Association of Cardiovascular Imaging.MethodsA total of 734 (mean age: 45.8 ± 13.3 years) healthy volunteers (320 men and 414 women) were enrolled at 22 collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study. A comprehensive echocardiographic examination was performed on all subjects following pre-defined protocols. There were no gender differences in age or cholesterol levels. Compared with men, women had significantly smaller body surface areas, and lower blood pressure. Quality of echocardiographic data sets was good to excellent in the majority of patients. Upper and lower reference limits were higher in men than in women. The reference values varied with age. These age-related changes persisted for most parameters after normalization for the body surface area.ConclusionThe NORRE study provides useful two-dimensional echocardiographic reference ranges for cardiac chamber quantification. These data highlight the need for body size normalization that should be performed together with age-and gender-specific assessment for the most echocardiographic parameters. © 2014 The Author.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-01-01 |