6533b820fe1ef96bd1279c91

RESEARCH PRODUCT

Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study

Gregorio SerraMario GiuffrèGiovanni SavarinoMaurizio CartaMarcello CimadorGiovanni CorselloIngrid Anne Mandy SchierzAntonio Corsello

subject

MaleParenteral Nutritionmedicine.medical_specialtyPediatricsEnteral formulasPreterm newbornsPopulationGestational AgeInfant Premature DiseasesPediatric surgeryPediatricsEnteral administrationRJ1-570Enteral NutritionPediatric nutritionEnterocolitis NecrotizingNecrotizing enterocolitismedicineHumansInfant Very Low Birth WeightNecrotizing enterocolitiProspective StudieseducationProspective cohort studyPediatric gastroenterologySurvival ratePediatric gastroenterologyVery low birth weight infantsPreterm newborneducation.field_of_studyEnteral formulabusiness.industryResearchMortality rateInfant NewbornNECVitaminsInfant Low Birth Weightmedicine.diseasedigestive system diseasesParenteral nutritionNecrotizing enterocolitisFemaleNeonatologybusinessInfant Premature

description

AbstractNecrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC.

yearjournalcountryeditionlanguage
2021-11-01Italian Journal of Pediatrics
https://doi.org/10.1186/s13052-021-01180-8