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RESEARCH PRODUCT
Geometric Analysis of Type B Aortic Dissections Shows Aortic Remodeling After Intervention Using Multilayer Stents
Horatiu MoldovanJorn P. MeekelJorn P. MeekelCristian BucurenciuKak K. YeungKak K. YeungAnca M. ChiticGabriela CandeaCrina SolomonTatiana MelnicVictor S CostacheAndreea CostacheIulian Vasile Antoniacsubject
Materials scienceGeometric analysisHemodynamics3d modelcomputational fluid dynamics030204 cardiovascular system & hematologylcsh:TechnologyArticle03 medical and health sciences0302 clinical medicinemedicineMedical imagingGeneral Materials Scienceaortic dissectionlcsh:Microscopylcsh:QC120-168.85Aortic dissectionlcsh:QH201-278.5multilayer flow modulatorlcsh:Tmedicine.diseaseaortic remodelinggeometric analysisLumen DiameterFlow velocitylcsh:TA1-2040lcsh:Descriptive and experimental mechanicslcsh:Electrical engineering. Electronics. Nuclear engineeringlcsh:Engineering (General). Civil engineering (General)lcsh:TK1-9971030217 neurology & neurosurgeryBiomedical engineeringLumen (unit)description
Recently, multilayer stents for type B aortic dissections (TBAD) have been proposed to decrease false lumen flow, increase and streamline true lumen flow, and retain branch vessel patency. We aimed to provide a protocol with standardized techniques to investigate aortic remodeling of TBAD by multilayer flow modulators (MFM) in static geometric and hemodynamic analyses. Combining existing literature and new insights, a standardized protocol was designed. Using pre- and postoperative CT scans, geometric models were constructed, lumen dimensions were calculated, computational fluid dynamics (CFD) models were composed, and velocity and pressures were calculated. Sixteen TBAD cases treated with MFM were included for analysis. For each case, aortic remodeling was analyzed using post-processing medical imaging software. After 3D models were created, geometrical anatomical measurements were performed, and meshes for finite element analysis were generated. MFM cases were compared pre- and postoperatively
year | journal | country | edition | language |
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2020-05-01 | Materials |