6533b831fe1ef96bd12984b5
RESEARCH PRODUCT
Association between Proinflammatory Markers, Leukocyte–Endothelium Interactions, and Carotid Intima–Media Thickness in Type 2 Diabetes: Role of Glycemic Control
Francisco CanetVictor M. VictorAranzazu M. De MarañónMilagros RochaZaida Abad-jiménezSandra López-domènechPedro Díaz-pozoIldefonso Roldan-torresFrancesca IannantuoniCarlos Morillassubject
medicine.medical_specialtyEndotheliumPopulationlcsh:MedicineInflammationType 2 diabetes030204 cardiovascular system & hematologyGastroenterologyArticleProinflammatory cytokine03 medical and health scienceschemistry.chemical_compound0302 clinical medicineendothelial functionInternal medicinemedicineeducationcarotid intima–media thickness030304 developmental biologyGlycemic0303 health scienceseducation.field_of_studybusiness.industrylcsh:RGeneral Medicinemedicine.diseasemedicine.anatomical_structurechemistryIntima-media thicknessinflammationGlycated hemoglobintype 2 diabetesmedicine.symptombusinessglycated hemoglobindescription
Glycated hemoglobin monitorization could be a tool for maintaining type 2 diabetes (T2D) under control and delaying the appearance of cardiovascular events. This cross-sectional study was designed to assess the role of glycemic control in modulating early-stage markers of cardiovascular complications. One hundred and eight healthy controls and 161 type 2 diabetic patients were recruited and distributed according to their glycemic control, setting the threshold at 6.5% (good control). Biochemical and anthropometrical parameters were registered during the initial visit, and peripheral blood was extracted to obtain polymorphonuclear cells and analyze inflammatory markers, adhesion molecules, leukocyte&ndash
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-08-05 | Journal of Clinical Medicine |