6533b834fe1ef96bd129cb71

RESEARCH PRODUCT

Altered neural responses to social fairness in bipolar disorder

Eva Elisa SchneiderMichèle WessaGiannis LoisAleksandra Kaurin

subject

Audiologylcsh:RC346-4290302 clinical medicineSocial decision makingRATING-SCALEBRAINSocial informationhealth care economics and organizationsBrain Mappingmedicine.diagnostic_test05 social sciencesRegular ArticleMagnetic Resonance ImaginghumanitiesNeurologyFMRIECONOMIC DECISION-MAKINGlcsh:R858-859.7Fairness ; Bipolar disorder ; Ambiguity ; Ultimatum game ; Social decision-makingmedicine.symptomPsychologyPsychosocialpsychological phenomena and processesUltimatum gamemedicine.medical_specialtyAmbiguityFairnessSocial decision-makingBipolar disorderCognitive NeuroscienceDecision MakingImpulsivitylcsh:Computer applications to medicine. Medical informaticsbehavioral disciplines and activities050105 experimental psychologyMECHANISMS03 medical and health sciencesmental disordersmedicineContextual informationHumans0501 psychology and cognitive sciencesRadiology Nuclear Medicine and imagingBipolar disorderSocial BehaviorINSULAMETAANALYSISlcsh:Neurology. Diseases of the nervous systemPERFORMANCEmedicine.diseaseGames ExperimentalIMPULSIVENESSNeurology (clinical)Functional magnetic resonance imagingInsula030217 neurology & neurosurgery

description

Highlights • Bipolar disorder is characterized by impaired processing of social fairness. • BD patients exhibit increased rejection of moderate unfairness in Ultimatum Game. • BD patients display decreased response to moderate unfairness in anterior insula. • BD patients deactivate posterior and middle insula in response to unfairness. • Trait impulsivity positively correlated with deactivations in posterior insula.

yearjournalcountryeditionlanguage
2020-01-01NeuroImage: Clinical
10.1016/j.nicl.2020.102487http://www.sciencedirect.com/science/article/pii/S2213158220303247