6533b834fe1ef96bd129cdfc

RESEARCH PRODUCT

RNA dependent DNA polymerase in cells of xeroderma pigmentosum

G. W. KortingRudolf K. ZahnZen-ichi YamazakiWerner E. G. M�llerG. Brehm

subject

Xeroderma pigmentosumHepatitis B virus DNA polymeraseDNA polymeraseDNA polymerase IIDeoxyribonucleotidesPolynucleotidesBiophysicsRNA-dependent RNA polymeraseTritiummedicine.disease_causeRauscher VirusBiochemistryMicemedicineAnimalsChemical PrecipitationHumansMolecular BiologySkinchemistry.chemical_classificationXeroderma Pigmentosumintegumentary systembiologyRNA virusDNATemplates GeneticCell BiologyRibonucleotidesmedicine.diseasebiology.organism_classificationVirologyMolecular biologyStimulation ChemicalEnzymechemistryAmmonium SulfateDNA Nucleotidyltransferasesbiology.proteinRNAFemaleGuanosine TriphosphateCarcinogenesis

description

Abstract Cells from X.P. ∗ skin contain an RNA dependent DNA polymerase, while in cells from normal skin this enzyme is lacking. This finding stimulates the thought that carcinogenesis in X.P. cells is due to an infection with an oncogenic RNA virus.

yearjournalcountryeditionlanguage
1971-07-16Biochemical and Biophysical Research Communications
https://doi.org/10.1016/0006-291x(71)90619-x