6533b837fe1ef96bd12a27a6
RESEARCH PRODUCT
Pharmacological properties of the methanol extract from Mentha suaveolens Ehrh.
L. MorenoJuan V. EspluguesEduardo Primo-yúferaR. Bellosubject
PainStimulationPharmacognosyCarrageenanlaw.inventionchemistry.chemical_compoundMicefoodIn vivolawmedicineAnimalsEdemaRats WistarPain MeasurementPharmacologyAnalgesicsTraditional medicinebusiness.industryPlant ExtractsMentha suaveolensAnti-Inflammatory Agents Non-SteroidalBiological activityfood.foodRatsPlant LeaveschemistryFemalePhytotherapybusinessHistamineAcetylcholinemedicine.drugMenthaPhytotherapydescription
The present study analyses the pharmacological activity in in vivo and in vitro models of the methanol extract obtained from the leaves and steams of Menta suaveolens Ehrh. This extract lacked toxicity, but exhibited a central nervous system depressant action; an analgesic effect in models of chemical and mechanical stimulation suggesting the induction of a peripheral analgesic response. The extract also exhibited an antiinflammatory action inhibiting the rat paw oedema induced by carrageenin. Moreover, the in vitro studies showed a significant diminution in the contractile effects induced by histamine, serotonin and acetylcholine.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2002-04-05 | Phytotherapy research : PTR |