6533b851fe1ef96bd12aa0ca

RESEARCH PRODUCT

Polymer Complexes in Biological Applications

Seah Ling KuanHeiko J. LuhmannManfred SchmidtFrauke KuehnKlaus MüllenYuzhou WuTanja WeilEweline PietrowskiSandra MuthMike SahlJana Hedrich

subject

chemistry.chemical_classificationMaterials scienceNanotechnologyPolymerHuman serum albuminPolyelectrolyteCaveolae-mediated endocytosisPlasmid dnachemistryDendrimerDrug deliverymedicineOrganic chemistryTopology (chemistry)medicine.drug

description

This chapter summarizes the influence of polyelectrolyte topology on biological functions and biomedical applications such as cell uptake, drug delivery, and gene transfection. Polyelectrolytes utilized are spherical structures derived from dendrimers and albumin or cylindrical brushes, all of which are decorated with various polypeptide chains.

https://doi.org/10.1007/12_2013_229