6533b855fe1ef96bd12b0afd

RESEARCH PRODUCT

Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination

Sergio IndelicatoSerena IndelicatoConcetta ArcadipaneErnesto TranchinaLeopoldo CerauloFilippo GiambartinoDavid BongiornoGiuseppe Avellone

subject

medicine.medical_specialtyArticle SubjectGeneral Chemical EngineeringMetabolitePopulationlcsh:Analytical chemistrySpme gc msUrineSevofluraneAnalytical Chemistrychemistry.chemical_compoundDesfluraneanesthetics desflurane sevofluranehexafluoroisopropanolMedicineeducationInstrumentationeducation.field_of_studylcsh:QD71-142Chromatographybusiness.industryContaminationComputer Science ApplicationsSurgeryUrine levelschemistrybusinessResearch Articlemedicine.drug

description

In this work, a new sensitive analytical method has been developed and evaluated for the determination of the most commonly used gaseous anesthetics, desflurane, sevoflurane, and this latter’s hepatic metabolite hexafluoroisopropanol (HFIP) in the urine. In addition, an evaluation of anesthetics exposition on the urine levels of a small population of surgical operators has been performed and results are briefly discussed.

https://doi.org/10.1155/2014/753237