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6533b859fe1ef96bd12b8106

RESEARCH PRODUCT

A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death

Blanche L. NdontsaYves M.m. NguekeuİLhami ÇElikRoukayatou MbouangouerePierre TaneVictor KueteThomas EfferthArmelle T. Mbaveng

subject

0301 basic medicineProgrammed cell deathCytotoxicitySaponinPharmaceutical ScienceApoptosisFlow cytometryCell Cycle Distribution03 medical and health sciencesArdisiacrispin BCell Line TumorDrug DiscoverymedicineFerroptosisHumansCytotoxic T cellOleanolic AcidCytotoxicityCaspaseMembrane Potential MitochondrialPharmacologybiologymedicine.diagnostic_testMitochondrial Membrane PotentialChemistryHep G2 CellsSaponinsHCT116 Cellsmedicine.diseaseAntineoplastic Agents PhytogenicDrug Resistance MultipleLeukemia030104 developmental biologyComplementary and alternative medicineDoxorubicinDrug Resistance NeoplasmApoptosisCaspasesCancer cellbiology.proteinCancer researchMolecular MedicineReactive Oxygen Species

description

WOS: 000432722700010

yearjournalcountryeditionlanguage
2018-04-01Phytomedicine
https://doi.org/10.1016/j.phymed.2018.03.035
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