6533b85dfe1ef96bd12be044
RESEARCH PRODUCT
Obesity and Cardiometabolic Risk Factors : from Childhood to Adulthood
Artur MazurElke WühlVesna Herceg-čavrakDorota DrozdzMichał BrzezińskiJulio AlvarezRosita GabbianelliClaudio BorghiBeatriz González López-valcárcelMałgorzata WójcikEmpar Lurbesubject
EpigenomicsMaleGerontologyPediatric ObesityobesityInfants Alimentacióobesity ; cardiometabolic risk factors ; hypertension ; dyslipidemia ; tracking phenomenon ; nutrigenomicsReviewType 2 diabetesnutrigenomicPregnancytracking phenomenon.TX341-641ChildPrenatal Nutritional Physiological PhenomenaMetabolic Syndromeeducation.field_of_studyNutrition and Dieteticscardiometabolic risk factorNutrigenomicsCardiorespiratory FitnessCardiovascular DiseasesChild PreschoolObesitatFemaleAdulttracking phenomenonhypertensionAdolescentPopulationChildhood obesityYoung AdultnutrigenomicsmedicineMortalitatHumansAdultseducationbusiness.industryNutrition. Foods and food supplydyslipidemiaInfant NewbornInfantCardiorespiratory fitnessmedicine.diseaseObesitycardiometabolic risk factorsDietMetabolic syndromebusinessDyslipidemiaFood Sciencedescription
Obesity has become a major epidemic in the 21st century. It increases the risk of dyslipidemia, hypertension, and type 2 diabetes, which are known cardiometabolic risk factors and components of the metabolic syndrome. Although overt cardiovascular (CV) diseases such as stroke or myocardial infarction are the domain of adulthood, it is evident that the CV continuum begins very early in life. Recognition of risk factors and early stages of CV damage, at a time when these processes are still reversible, and the development of prevention strategies are major pillars in reducing CV morbidity and mortality in the general population. In this review, we will discuss the role of well-known but also novel risk factors linking obesity and increased CV risk from prenatal age to adulthood, including the role of perinatal factors, diet, nutrigenomics, and nutri-epigenetics, hyperuricemia, dyslipidemia, hypertension, and cardiorespiratory fitness. The importance of ‘tracking’ of these risk factors on adult CV health is highlighted and the economic impact of childhood obesity as well as preventive strategies are discussed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-01-01 |