6533b85efe1ef96bd12bf461

RESEARCH PRODUCT

The Structure and the Stereochemistry of Atractyliretin

Conrado PascualLeopoldo CerauloLorenzo CamardaVincenzo SprioMirella Ferrugia

subject

PharmacologyStereochemistryChemistryOrganic ChemistryPharmaceutical ScienceToxic substanceAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicineDrug DiscoveryMolecular MedicineMoleculeAcid hydrolysisAtractylosideDiterpeneChemical decompositionAtractylis gummifera

description

The nor-kaurane diterpene Atractyliretin was obtained by acid hydrolysis of Atractyloside, a toxic substance isolated from ATRACTYLIS GUMMIFERA L (Compositae). On the basis of spectral (IR, (1)H-NMR, (13)C-NMR and MS) analysis and chemical degradation its structure and stereochemistry was identified as 4.

https://doi.org/10.1055/s-2007-969185