0000000000057505
AUTHOR
Lorenzo Camarda
Qualità, efficacia, sicurezza per il paziente trapiantato: valutazione e confronto della stabilità di due sospensioni magistrali di Tacrolimus
Chemical composition and antimicrobial activity of some oleogum resin essential oils from Boswellia spp. (Burseraceae).
The chemical composition of Boswellia carteri (Somalia), B. papyrifera (Ethiopia), B. serrata (India) and B. rivae (Ethiopia) oleogum resin essential oils was investigated using GC-MS to identify chemotaxonomy marker components. Total ion current peak areas gave good approximations to relative concentrations based on GC-MS peak areas. B. carteri and B. serrata oleogum resin oils showed similar chemical profiles, with isoincensole and isoincensole acetate as the main diterpenic components. Both n-octanol and n-octyl acetate, along with the diterpenic components incensole and incensole acetate, were the characteristic compounds of B. papyrifera oleogum resin oil. Hydrocarbon and oxygenated mo…
Traditional medicine as a source of new therapeutic agents against psoriasis.
In the frame of traditional medicine, the use in the treatment of psoriasis of some plants typical of the flora of Sicily is reported. A preliminary search on some plants used for the treatment of psoriasis in Asia, South America and Africa is also reported.
Studio dei costituenti terpenoidici di oleo-resine di origine africana
ANTIPROLIFERATIVE ACTIVITY OF CITRUS JUICES AND HPLC EVALUATION OF THEIR FLAVONOID COMPOSITION
The antiproliferative activity of fresh fruit juices extracted from Citrus sinensis (cv. Washington Navel and cv. Sanguinello), C. deliciosa cv. Avana, C. clementina cv. Nules, C. aurantium subsp. myrtifolia , was evaluated against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. All the juices tested showed antiproliferative activity. Moreover, the pattern of the main flavanone compounds in the juices has been determined by HPLC analysis.
Essential oil of inflorescences of Eryngium campestre L. (Apiaceae)
Mass Spectrometry of Simple Indoles. Part 2: Fourier Transform Mass spectrometry, Fast Atom Bombardment, Laser Desorption and Electrospray Ionisation. TARGETS IN HETEROCYCLIC SYSTEMS: CHEMISTRY AND PROPERTIES
Volatile compounds of fresh fruits of Phillyrea latifolia L.
The volatiles constituents of fresh fruits of Phillyrea latifolia were submitted to investigation by GC-MS. The plants grows wild in different zones of the mediterranean region and its leaves and fruits are used as astringent, diuretic and anti-inflammatory. The volatiles were sampled by solid-phase microextraction (SPME), with a 100 mm polydimethylsiloxane fibre a 50 °C for 1 h. The headspace main components of fresh fruits of Phillyrea latifolia included limonene, β-cariophillene, eremophilene, α-muurolene, β -eudesmol e spatulenol.
Chemical investigation and antibacterial activity of some Boswellia essential oils
Gas-phase ion chemistry of protonated melatonin
The gas-phase ion chemistry of protonated melatonin has been investigated by mass spectrometric (MS) techniques involving chemical ionisation, fast atom bombardment and electrospray ionisation. Either naturally- occurring or collision-induced decomposition e-D derivatives obtained by exchange with D(2)O. The analysis of experimental results allows definite pathways for the formation of the ion at m/z 174 to be assigned and sheds some more light on the overall fragmentation pathways. Experiments on labelled derivatives evidenced H-D scrambling processes during fragmentation
ATTIVITA' ANTIBIOFILM DI OLI ESSENZIALI OTTENUTI DA RESINE NATURALI DEL GENERE BOSWELLIA (BURSERACEAE)
COMPOSIZIONE CHIMICA E ATTIVITA' BIOLOGICA DI OLI ESSENZIALI OTTENUTI DA RESINE NATURALI DEL GENERE BOSWELLIA(BURSERACEAE)
Gas-phase ion chemistry of protonated melatonin
The gas-phase ion chemistry of protonated melatonin has been investigated by mass spectrometric (MS) techniques involving chemical ionisation, fast atom bombardment and electrospray ionisation. Either naturally-occurring or collision-induced decomposition experiments have been carried out using side chain tetra-deuterium-labelled derivatives, as well as the corresponding N–D derivatives obtained by exchange with D2O. The analysis of experimental results allows definite pathways for the formation of the ion at m/z 174 to be assigned and sheds some more light on the overall fragmentation pathways. Experiments on labelled derivatives evidenced H–D scrambling processes during fragmentation.
Metodiche analitiche per la determinazione di fitofarmaci in matrici acquose
In vitro anti-biofilm activity of Boswellia spp. oleogum resin essential oils
Aims: To evaluate the anti-biofilm activity of the commercially available essential oils from two Boswellia species. Methods and Results: The susceptibility of staphylococcal and Candida albicans biofilms was determined by methyltiazotetrazolium (MTT) staining. At concentrations ranging from 217·3 μg ml−1 (25% v/v) to 6·8 μg ml−1 (0·75% v/v), the essential oil of Boswellia papyrifera showed considerable activity against both Staphylococcus epidermidis DSM 3269 and Staphylococcus aureus ATCC 29213 biofilms. The anti-microbial efficacy of this oil against S. epidermidis RP62A biofilms was also tested using live/dead staining in combination with fluorescence microscopy, and we observed that …
Essential Oil of Leaves and Fruits ofAthamanta siculaL. (Apiaceae)
Abstract The essential oils obtained separately from the leaves and the fruits of Athamanta sicula L. collected in Sicily were studied by capillary GC/MS. The main component in the leaf oil was myristicin (97.6%), while β-pinene (2.8%), β-phellandrene (5.8%), δ-3-carene (22.6%), terpinolene (20.5%) and myristicin (41.3%) were the main components of the fruit oil.
Analisi qualitativa dei costituenti cumarinici presenti in campioni di manna prodotti da esemplari di Fraxinus angustifolia (Oleaceae) delle Madonie
Composizione chimica dell'olio essenziale di Ptilostemon greuteri (Compositae)
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 7-SUBSTITUTED1-ETHYL-3,4,10-TRIMETHYL-1,10-DIHYDRO-11H-PYRAZOLO(3,4-c)(1,6)BENZODIAZOCIN-11-ONE: A NEW RING SYSTEM
Derivatives of the title ring system of type 10 were obtained in good yield by fusion of the intermediates 12. Attempt to cyclize the acetylamino derivative 9 under Bischler-Napieralski conditions failed because of the insufficient electronic density in the position 4 of the pyrazole ring created by the adjacent carbonyl moiety. The derivatives of the new ring system, assayed as anxiolytic agents, showed no significant activity.
Valutazione della stabilità in due sospensioni magistrali di Tacrolimus
Homoisoflavonoids analysis in Dracaena draco fruits by HPLC-DAD-ESI-MS.
Gas-phase ion chemistry of protonated melatonin: naturally occurring and collision induced fragmentation
Chemical composition and antimicrobial activity of some oleogum resin essential oils from Boswellia spp. (Burseraceae)
The chemical composition of Boswellia carteri (Somalia), B. papyrifera (Ethiopia), B. serrata (India) and B. rivae (Ethiopia) oleogum resin essential oils was investigated using GC-MS to identify chemotaxonomy marker components. Total ion current peak areas gave good approximations to relative concentrations based on GCMS peak areas. B. carteri and B. serrata oleogum resin oils showed similar chemical profiles, with isoincensole and isoincensole acetate as the main diterpenic components. Both n-octanol and n-octyl acetate, along with the diterpenic components incensole and incensole acetate, were the characteristic compounds of B. papyrifera oleogum resin oil. Hydrocarbon and oxygenated mon…
In Vitro Antiproliferative properties and flavanone profiles of six grapefruit (Citrus paradisi Macf.) cultivars
Costituenti flavonoidici isolati da Dracaena draco (Dracaenaceae)
Rapid determination of volatile constituents of Cachrys Sicula L. (Apiaceae) by gas chromatography-mass spectrometry with solid-phase microextraction
The Structure and the Stereochemistry of Atractyliretin
The nor-kaurane diterpene Atractyliretin was obtained by acid hydrolysis of Atractyloside, a toxic substance isolated from ATRACTYLIS GUMMIFERA L (Compositae). On the basis of spectral (IR, (1)H-NMR, (13)C-NMR and MS) analysis and chemical degradation its structure and stereochemistry was identified as 4.
Chemical Composition of Essential Oils from Athamanta sicula
The genus Athamanta L. (Apiaceae) consists of about nine species, which are distributed mainly in southeastern Europe. Some of the Athamanta species are used in traditional medicine as antiseptics, diuretics, and in the therapy of sclerosis [1]. Phytochemical studies of species from the genus Athamanta report the presence of coumarins [2–5], flavonoids [6], and fatty acids [7]. Athamanta sicula L. is an annual perennial herb, growing to a height of 30 to 100 cm. It occurs in calcareous vertical cliffs 100 meters to 1500 meters above sea level and is widespread in South Italy, particularly in Sicily. In the popular medicine, it is known as “spaccapietre” (rock splitters), and infusions of it…