Synthesis and biological evaluation of dehydroabietic acid derivatives.

6533b85efe1ef96bd12bfd85

RESEARCH PRODUCT

Synthesis and biological evaluation of dehydroabietic acid derivatives.

Ana Cecilia Mesa-arango Liliana Betancur-galvis Bibiana Zapata Julieth Correa-royero Miguel A. González Lee Agudelo David Perez-guaita

subject

Ketone Antifungal Agents Carboxylic acid Antineoplastic Agents Herpesvirus 1 Human Microbial Sensitivity Tests Aldehyde Chemical synthesis Antiviral Agents chemistry.chemical_compound Inhibitory Concentration 50 Cell Line Tumor Drug Discovery Organic chemistry Animals Humans Abietic acid Cytotoxicity Pharmacology chemistry.chemical_classification Organic Chemistry Fungi food and beverages General Medicine equipment and supplies Terpenoid chemistry Abietanes lipids (amino acids peptides and proteins)Diterpene Hydrophobic and Hydrophilic Interactions

description

A series of C18-oxygenated derivatives of dehydroabietic acid were synthesized from commercial abietic acid and evaluated for their cytotoxic, antimycotic, and antiviral activities.

year	journal	country	edition	language
2010-02-01	European journal of medicinal chemistry

10.1016/j.ejmech.2009.10.010 https://pubmed.ncbi.nlm.nih.gov/19892441

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