6533b871fe1ef96bd12d11ef
RESEARCH PRODUCT
[Hearing impairment in patients with rheumatoid arthritis].
Carlos De Paula VernettaFrancisco Javier García CallejoIgnacio Alonso CastañeiraNoemi Conill TobíasNoelia Muñoz FernándezJaime Marco Algarrasubject
AdultMalemedicine.medical_specialtyHearing lossArthritisArthritis RheumatoidInternal medicinemedicineHumansIn patientHearing Lossmedicine.diagnostic_testbiologybusiness.industryCase-control studyGeneral MedicineMiddle Agedmedicine.diseaseSurgeryRheumatoid arthritisCase-Control Studiesbiology.proteinFemalePure tone audiometryAudiometryAntibodymedicine.symptombusinessdescription
To evaluate the characteristics of hearing loss (HL) in patients with rheumatoid arthritis (RA).A comparative case-control study was performed with 194 patients and 107 healthy subjects. All of them were submitted to pure-tone audiometry and detection of inflammatory parameters and Western blot for anticochlear antibodies.HL was detected in 42.7 % of patients with RA (15.9 % in controls; P.001). This was sensorineural in 38.6 %. Three or more altered blood parameters appeared in 28.9 % of patients with RA (17.6 % in controls; P.01). We observed positive Western blot in 12 % of patients with RA and HL and none among healthy controls.There is a predisposition to HL, mainly sensorineural, in RA. In view of this prevalence, audiologic reviews must be performed to try to determine if this disorder shows an immunomediated aspect so that a therapeutic alternative could modify the course of HL.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-08-01 | Acta otorrinolaringologica espanola |