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RESEARCH PRODUCT
Endoscopic ultrasonography in gastric lymphomas: appraisal on reliability in long-term follow-up
Calogero VetroCalogero VetroDaniela DonnarummaGiuseppe A. PalumboAlessandra RomanoAlessandra RomanoG. BonannoConcetta ConticelloAusilia GorgoneFrancesco Di RaimondoF. CoppolinoAnnalisa Chiarenzasubject
Cancer Researchmedicine.medical_specialtymedicine.diagnostic_testbusiness.industryMALT lymphomaRetrospective cohort studyHematologyGeneral Medicinemedicine.diseasedigestive system diseasesLymphomaSurgeryEndoscopyLymphatic systemOncologyimmune system diseaseshemic and lymphatic diseasesBiopsymedicineRadiologyYoung adultbusinessSurvival ratedescription
The reliability of endoscopic ultrasonography (EUS) in follow-up management of gastric lymphomas has not been clearly validated. We conducted a retrospective analysis on 23 patients, 12 affected by mucosa-associated lymphoid tissue (MALT) lymphoma, eight by diffuse large B-cell lymphoma, and three by high-grade lymphoma with low-grade component, all treated with a stomach-conservative approach. One hundred and twenty matched evaluations with both EUS and endoscopy with biopsy (E-Bx) were performed, according to validated guidelines and clinical judgment. At a median follow-up of 87 months ranged between 9.5 and 166 months, the analysis of progression-free survival and disease-free survival showed a strict relationship between the persistence of EUS abnormalities and the clinical outcome in patients with MALT lymphoma (p = 0.0079; p = 0.02) but not in patients with high-grade lymphoma. In conclusion, EUS evaluation does not seem reliable in follow-up management of high-grade lymphomas, although it could have a great clinical impact in the management of MALT lymphoma. Copyright © 2011 John Wiley & Sons, Ltd.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-12-20 | Hematological Oncology |