Near threshold photoproduction of eta mesons off the proton.

1995

We have measured precise total and differential cross sections for the reaction $\ensuremath{\gamma}p\ensuremath{\rightarrow}p\ensuremath{\eta}$ from threshold to 790 MeV at the MAMI accelerator in Mainz with the neutral meson spectrometer TAPS. Resonance parameters of the ${S}_{11}$(1535) resonance and the electromagnetic coupling $\ensuremath{\gamma}p\ensuremath{\rightarrow}{S}_{11}$ have been extracted from the data. Contributions from the ${D}_{13}$(1520) resonance to $\ensuremath{\eta}$ photoproduction in the threshold region have been identified for the first time via interference terms in the angular distributions.

Spin Glasses on Thin Graphs

1995

In a recent paper we found strong evidence from simulations that the Isingantiferromagnet on ``thin'' random graphs - Feynman diagrams - displayed amean-field spin glass transition. The intrinsic interest of considering such random graphs is that they give mean field results without long range interactions or the drawbacks, arising from boundary problems, of the Bethe lattice. In this paper we reprise the saddle point calculations for the Ising and Potts ferromagnet, antiferromagnet and spin glass on Feynman diagrams. We use standard results from bifurcation theory that enable us to treat an arbitrary number of replicas and any quenched bond distribution. We note the agreement between the f…

O6-methylguanine-DNA methyltransferase activity in breast and brain tumors.

1995

The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) is a main determinant of resistance of tumor cells to the cytostatic activity of chemotherapeutic alkylating agents (methylating and chloroethylating nitrosoureas) and is effective in protecting normal cells against genotoxic and carcinogenic effects resulting from DNA alkylation. Therefore, the level of expression of MGMT is significant for the response of both the tumor and the non-target tissue following application of nitrosoureas in tumor therapy. To determine the expression of MGMT in tumor tissue, we have assayed MGMT activity in 68 breast carcinomas and 38 brain tumors. There was a wide variation of MGMT expression…

WEAK DIPOLE MOMENTS AT ${\bf e^+e^-}$ COLLIDERS

1995

The weak dipole moments of leptons and quarks, \ie those related to their $Z$--coupling, are reviewed. Standard Model predictions and experimental results may result in a stringent test for both their pointlike structure and also for the Standard Model. Special attention is devoted to the anomalous weak--magnetic dipole moment and to the $CP$--violating weak--electric dipole moment.

Intérêt des modèles cellulaires d'interaction dans l'étude du pouvoir pathogène des colibacilles producteurs de CNF et des colibacilles responsables …

1995

Cytotoxines et fimbriae produites par des souches Escherichia coli isolées de veaux diarrhéiques en Algérie

1995

National audience

Synthesis of 8,9-dihydrodipyrazolo[3,4-b:4′,3′-f][1,5]diazocin-10(1H)-one. A new ring system

1995

8,9-Dihydrodipyrazolo[3,4-b:4′,3′-f][1,5]diazocin-10(1H)-ones 7 were prepared by cyclization of 1-ethyl-N,3-dimethyl-4-acetamido-N-(1-R1-3-R2-1H-pyrazol-5-yl)-1H-pyrazole-5-carboxamides 6 by a Bischler-Napieralski cyclization. A complete assignment of the chemical shifts to the carbon atoms of compound 7 was performed by different nmr experiments, such as DEPT and XHDEPT for onebond CH correlations and COLOC experiments for long-range C-H correlations.

Substituent effects on13C NMR parameters of chlorinated diphenyl ethers. A multiple linear regression analysis

1995

13C NMR chemical shifts and nJ(C,H) coupling constants of polychlorinated diphenyl ethers (PCDEs) were measured and analysed. The chlorine substituent effects on the chemical shifts and the coupling constants were determined by a multiple linear regression analysis. The 13C NMR chemical shifts depend on the conformational preferences in PCDEs. In addition to single substituent effects, corrective terms reflecting the conformational state of the molecule and the mutual steric interactions of two chlorine atoms had to be taken into account for the reliable prediction of the 13C chemical shifts. In contrast to chemical shifts, conformational effects play a minor role in the substituent effects…

Bivergent extension in orogenic belts: The Menderes massif (southwestern Turkey)

1995

The central Menderes massif is characterized by an overall dome-shaped foliation pattern and a north-northeast-trending stretching lineation. The asymmetry of shear bands and quartz c-axis fabrics on either side of the structural dome demonstrate a top to the north-northeast shear sense in the northern part and a top to the south-southwest shear sense in the southern part of the submassif, i.e., a bivergent downdip movement. This suggests a symmetric collapse of the Alpine Menderes orogenic belt along two extensional shear zones. Conjugate shear bands and symmetric quartz c-axis fabrics in the east-trending transition zone demonstrate a coaxial deformation between the two extension domains.…

Expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental …

1995

In situ hybridization, RT-PCR and Northern blot analysis as well immunohistochemistry were used to examine the expression of C1q, a subcomponent of the rat complement system, in brains of rats infected with Borna disease virus (BDV) and rats afflicted with experimental allergic encephalomyelitis (EAE) induced by the adoptive transfer of myelin basic protein specific T cells. C1q mRNA, which was not detected in normal brain, became clearly detectable using RT-PCR analysis by d14 post infection (p.i.) with BDV. Maximal levels of C1q mRNA were reached 21 days p.i. when inflammatory reactions in the brain were also at a peak. Similarly, C1q mRNA was elevated when the clinical symptoms of EAE be…

The distribution of the rotational transition strength in warm nuclei studied through γ-ray correlations

1995

Abstract The study of damping of rotational motion applying te rotational plane mapping (RPM) method is presented and discussed. The aim of this technique is to extract the distribution of the rotational transition strength from an analysis of the shape of the “central valley” of two- and three-dimensional γ-ray spectra. The method is applied to a triple γ-coincidence data set of 162,163Tm nuclei formed in 37Cl+130Te reactions. The rotational transition strength is obtained as a function of rotational frequency for selected regions of entry states, and the width is found to be rather constant and approximately equal to 80 keV. This value is significantly smaller than the value predicted the…

Cell Systems for Use in Studies on the Relationship Between Foreign Compound Metabolism and Toxicity

1995

: Since the metabolism of most foreign compounds is predominantly controlled by hepatic in metabolism, isolated hepatocytes in most cases quite well predict the pattern of the overall metabolism of a given compound. Methods have been developed for cryopreserving isolated hepatocytes from man and other species with satisfactory maintenance of foreign compound metabolizing enzyme activities. The installation of a bank of cryopreserved hepatocytes from different species is possible and may be used for rational species extrapolation. It is necessary for some toxicological investigations to have hepatocytes which retain their differentiated status in culture for a sufficient time period. This mi…

Macrosocial determinants of social integration: Social class and area effect

1995

Theory and research on social support have paid little attention to the existence of important macrosocial variables determining level and content of social relationships. This study examines variations in social integration as a function of social class and residential area characteristics. Results for 234 subjects living in high and low risk neighbourhoods indicated that differences between higher and lower social class groups follow different patterns in different residential areas. Also, same social class position appeared to have different significance as a function of residential area characteristics. The levels of three social integration measures—community integration and satisfacti…

Diagnostische Möglichkeiten und Behandlungsstrategien für die Fraktur der Eminentia intercondylica im Wachstumsalter

1995

Between 1970 and 1993 29 fractures of the intercondylar eminence were seen in children with almost the same number of cases showing no or minor displacement as those requiring open reduction for major dislocation. Combined knee injury must be suspected the higher the patient's age and the more pronounced the displacement of the fragment. Magnetic resonance imaging (MRI) has gained diagnostic predominance. Arthroscopy remains important for surgical management, especially of associated meniscus and cartilage damage. Early puncture of hemarthrosis is essential. Closed management is the therapy for nondisplaced fragments or those with bone contact or only tuberculum fractures--while displaced f…

Dioecy and its correlates in the flowering plants

1995

Thermodynamic parameters for the formation of glycine complexes with magnesium(II), calcium(II), lead(II), manganese(II), cobalt(II), nickel(II), zin…

1995

Abstract Protonation constants and Mg 2+ , Ca 2+ , Pb 2+ , Mn 2+ -, Co 2+ , Ni 2+ , Cu 2+ , Zn 2+  and Cd 2+ glycine complex formation constants have been determined in different aqueous media at different temperatures. Salt effects are explained by a complex formation model which takes into account the formation of weak species. From the temperature dependence of the formation constants, thermodynamic parameters ΔH θ (and in some cases ΔC θ p ) have been obtained. A rigorous analysis of literature data, together with experimental findings, allows recommended formation parameters, in the ranges 0 ≤ I e ≤ 1 mol l −1 ( I e is the effective ionic strength) and 5°C ≤ T ≤ 45°C, to be obt…

Dielectric Measurements on SBN:Ce

1995

Seroquel (ICI 204 636), a putative "atypical" antipsychotic, in schizophrenia with positive symptomatology: results of an open clinical trial and cha…

1995

Preclinical data indicated that seroquel (ICI 204 636), a dibenzothiazepine with 5-HT2 and D2-like receptor antagonistic properties, might be an effective antipsychotic agent, causing fewer extrapyramidal side effects than typical neuroleptics. In the present study, 12 patients suffering from schizophrenia or schizophreniform disorder with predominantly positive symptomatology were treated in an open clinical trial for 4 weeks with seroquel at a maximum dosage of 750 mg/day. The drug was generally well tolerated, and virtually no adverse extrapyramidal side effects such as acute dystonia, parkinsonism or akathisia were observed. Total scores for BPRS (item score 0–6; baseline: 42.0±2.3; mea…

Testing Mode-Coupling Theory for a Supercooled Binary Lennard-Jones Mixture I: The van Hove Correlation Function

1995

We report the results of a large scale computer simulation of a binary supercooled Lennard-Jones liquid. We find that at low temperatures the curves for the mean squared displacement of a tagged particle for different temperatures fall onto a master curve when they are plotted versus rescaled time $tD(T)$, where $D(T)$ is the diffusion constant. The time range for which these curves follow the master curve is identified with the $\alpha$-relaxation regime of mode-coupling theory (MCT). This master curve is fitted well by a functional form suggested by MCT. In accordance with idealized MCT, $D(T)$ shows a power-law behavior at low temperatures. The critical temperature of this power-law is t…

Thermogravimetric and calorimetric studies of water absorbed in polyaniline

1995

Abstract Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) were used to study the behavior of residual water absorbed by an emeraldine base and a salt of chemically synthesized polyaniline (PANI—EB, PANI-ES). The matrix of PANI is shown to contain water molecules participating in both reversible and irreversible absorption. In its turn, the reversibly absorbed water consists of two components. The first component (WD 1 ) amounts to 5–7 wt.% and is removable from PANI-EB in a flow of dry nitrogen at room temperature. The second one (6–8 wt.%) of more strongly bonded water (WD 2 ) can be withdrawn from PANI-EB at temperatures from 70 to 150 °C depending on the measu…

Photoelectron spectroscopy of thin discontinuous metal films deposited onto a sapphire substrate

1995

Abstract The charging of small metallic clusters forming discontinuous gold and gallium films, condensed in vacuum onto an insulating substrate (sapphire), was experimentally studied by the method of ultraviolet photoelectron spectroscopy (UPS) for a photon energy of 5.4 eV. It seems that the charging is due to electron emission as well as to electron transfer from metal islands to the empty electron states in the metal-insulator interface.

Cellular and molecular mechanisms in the induction phase of contact sensitivity.

1995

During the induction phase of contact sensitivity, hapten-specific Th1 cells are primed by epidermal Langerhans cells. These Langerhans cells present hapten on MHC class II molecules and provide costimulatory signals. This presentation discusses the induction of cytokines in Langerhans cells and keratinocytes by haptens and their regulatory effects on contact sensitivity. Haptens were painted on the skin of normal BALB/c mice and epidermal cells were prepared at various times thereafter. Langerhans cell-derived interleukin (IL)-1 beta mRNA was observed as early as 15 min after hapten paining. In keratinocytes, tumor necrosis factor-alpha, IL-1 alpha, IP-10, MIP-2 and IL-10 were found to be …

Measurement and Analysis of the Raman Intensities of 12CD4

1995

0022-2852; The stimulated Raman spectrum of 12CD4 was recorded at high resolution, in the spectral range 1963 to 2260 cm(-1). Intensities of the rovibrational transitions were estimated by fitting the line profiles. The recorded elementary spectrum was 1 cm(-1) wide; all recordings were then intensity calibrated. Afterward, the relative Raman intensities were analyzed by using a polarizability model developed previously [A. Boutahar and M. Loete, Can. J. Phys. 69, 26-35 (1991); J. P. Champion, M. Loete, and G. Pierre, in ''Spectroscopy of the Earth's Atmosphere and Interstellar Molecules'' (K. Narahari Rao and A. Weber, Eds.), pp. 388-397, Academic Press, Boston. 1992]. The investigated reg…

Special Relativity and the Single Antiproton: Fortyfold Improved Comparison ofp¯andpCharge-to-Mass Ratios

1995

The measured ratio of charge-to-mass ratios for the antiproton and proton is $1.0000000015\ifmmode\pm\else\textpm\fi{}0.0000000011$. This $1$ part in ${10}^{9}$ comparison ( $1$ ppb) is possible because a single $\overline{p}$ or $p$ is now directly observed while trapped in an open access Penning trap. The comparison is the most accurate mass spectrometry of particles with opposite charge, and is the most sensitive test of $\mathrm{CPT}$ invariance for a baryon system. It is 40 times more accurate than our earlier comparison with many trapped antiprotons and protons, and is more than 45 000 times more accurate than earlier comparisons made with other techniques.

Discreteness effects on the double sine-Gordon kink.

1995

A Palaeoenvironmental Study in Semi-arid Southeastern Spain: the Palynological and Sedimentological Sequence at Perneras Cave (Lorca, Murcia)

1995

Abstract Results are presented of palynological and sedimentological research at the Palaeolithic site of Perneras Cave (coastal Murcia, southeastern Spain). Sedimentological features point to a warm, somewhat humid phase corresponding with the lowermost part of the Mousterian sequence, which was followed by a climatic deterioration which lasted throughout the later Mousterian and Upper Palaeolithic. The palynological study described here barely allows palaeoclimatological inferences to be drawn, but it does highlight interesting paleobotanical data, namely, the presence of Ibero-Maghrebian and Mediterranean elements, which suggest that the site was an important refuge for thermophilous tax…

Dinuclear Rh(II) complexes in styrene hydroformylation. Enhancement of catalytic activity through orthometalation

1995

Three dirhodium(II) compounds including orthometalated PPh3 ligands have been tested as catalytic precursors for the hydroformylation of styrene. The activities obtained and the wide range of selectivities have been compared to the same reaction performed with RhH(CO)(PPh3)3, Rh2(O2CCH3)4 and various amounts of triphenylphosphine.

Die fiberendoskopische Intubation: Ausbildung in der Technik

1995

End-Group-Dominated Molecular Order in Self-Assembled Monolayers

1995

Dynamic properties of some β-chain mutant hemoglobins

1995

The thermal behavior of the Soret band relative to the carbonmonoxy derivatives of some beta-chain mutant hemoglobins is studied in the temperature range 300-10 K and compared to that of wild-type carbonmonoxy hemoglobin. The band profile at various temperatures is modeled as a Voigt function that accounts for homogeneous broadening and for the coupling with high- and low-frequency vibrational modes, while inhomogeneous broadening is taken into account with a gaussian distribution of purely electronic transition frequencies. The various contributions to the over-all bandwidth are singled out with this analysis and their temperature dependence, in turn, gives information on structural and dy…

Pathogenicity of live bacteria and extracellular products of motileAeromonasisolated from eels

1995

The pathogenic activities in vitro and in vivo of live bacteria and extracellular products (ECP) of 24 motile Aeromonas strains were investigated. Most Aer. hydrophila and Aer. jandaei isolates were pathogenic for eels (LD50 105·4‐107·6 cfu fish‐1) but no Aer. sobria, Aer. caviae and Aer. allosaccharophila caused mortality in eels at doses of > 108·4 cfu fish‐1. Of these Aeromonas strains, Aer. hydrophila and Aer. jandaei in particular produced elastases and haemolysins against fish erythrocytes. ECP from Aer. hydrophila and Aer. jandaei caused degenerative changes in fish cell lines and were strongly toxic for eels (LD50 1·0–3·2 μg (g fish)‐1) reproducing the symptoms associated with natur…

Feasibility of 1 arcmin resolution gamma-ray air-Čerenkov multiple telescope experiment

1995

Abstract In this paper we discuss the feasibility of a ground based detector exploiting the technique of Cerenkov light stereo imaging of air showers for the detection of discrete cosmic sources of γ-rays with energy threshold of 100 GeV, angular resolution (HWHM) of 1 arcmin ( 1 3 mrad), cosmic ray background rejection ≥ 99%. This experiment will make possible a deep survey of the sky with sensitivity of 1 100 of the Crab in 45 h of exposure.

Combined description of N-barN scattering and annihilation with a hadronic model.

1995

A model for the nucleon-antinucleon interaction is presented which is based on meson-baryon dynamics. The elastic part is the {ital G}-parity transform of the Bonn {ital NN} potential. Annihilation into two mesons is described in terms of microscopic baryon-exchange processes including all possible combinations of {pi},{eta},{rho},{omega},{ital a}{sub 0},{ital f}{sub 0},{ital a}{sub 1},{ital f}{sub 1},{ital a}{sub 2},{ital f}{sub 2},{ital K},{ital K}{sup *}. The remaining annihilation part is taken into account by a phenomenological energy- and state-independent optical potential of Gaussian form. The model enables a simultaneous description of nucleon-antinucleon scattering and annihilatio…

Leucocytozoon muscicapa n. sp. (Leucocytozoidae: Apicomplexa) from the pied flycatcherFicedula hypoleuca (Pallas) (Passeriformes: Muscicapinae)

1995

Leucocytozoon muscicapa n. sp. is described from the pied flycatcherFicedula hypoleuca (Pallas) (Passeriformes: Muscicapinae) from Finland and compared with other leucocytozoids of the family Muscicapidae.

‘‘Improved’’ lattice study of semileptonic decays ofDmesons

1995

We present results of a lattice computation of the matrix elements of the vector and axial-vector currents which are relevant for the semi-leptonic decays $D \rightarrow K$ and $D \rightarrow K^*$. The computations are performed in the quenched approximation to lattice QCD on a $24^3 \times 48$ lattice at $\beta=6.2$, using an $O(a)$-improved fermionic action. In the limit of zero lepton masses the semi-leptonic decays $D \rightarrow K$ and $D \rightarrow K^*$ are described by four form factors: $f^{+}_K,V,A_1$ and $A_2$, which are functions of $q^2$, where $q^{\mu}$ is the four-momentum transferred in the process. Our results for these form factors at $q^2=0$ are: $f^+_K(0)=0.67 \er{7}{8}$…

Equilibrium studies in natural waters: Speciation of phenolic compounds in synthetic seawater at different salinities

1995

Interactions between some phenolic compounds and macro-constituents of synthetic seawater (Na{sup +}, K{sup +}, Ca{sup 2+}, Mg{sup 2+}, Cl{sup {minus}}, and SO{sub 4}{sup 2{minus}}), at 20, 35, and 45 {per_thousand} salinity, have been investigated potentiometrically by using the [H]-glass electrode. The formation constants of phenol, o- and p-cresol, o-a dn p-nitrophenol complexes with sodium, potassium, calcium, and magnesium ions have been determined in the ionic strength range 0 {le} I {le} 1 mol/L. A comparison between the apparent protonation constants of phenols determined in synthetic seawater, and those simulated by a suitable complex formation model, is discussed. The possibility …