showing 36 of ~574560 from 574555 documents
Prospects of Decarbonizing Industrial Areas in the Baltic States by Means of Alternative Fuels
2022
This work has been supported by the National Research Programme, project “Trends, Challenges and Solutions of Latvian Gas Infrastructure Development” (LAGAS), No. VPP-EM-INFRA-2018/1-0003.
Valodniecība. Literatūrzinātne. Folkloristika: tēžu krājums
2022
Machine Learning–Enabled Multimodal Fusion of Intra-Atrial and Body Surface Signals in Prediction of Atrial Fibrillation Ablation Outcomes
2022
Background: Machine learning is a promising approach to personalize atrial fibrillation management strategies for patients after catheter ablation. Prior atrial fibrillation ablation outcome prediction studies applied classical machine learning methods to hand-crafted clinical scores, and none have leveraged intracardiac electrograms or 12-lead surface electrocardiograms for outcome prediction. We hypothesized that (1) machine learning models trained on electrograms or electrocardiogram (ECG) signals can perform better at predicting patient outcomes after atrial fibrillation ablation than existing clinical scores and (2) multimodal fusion of electrogram, ECG, and clinical features can furt…
Analysis of digital competence in future teachers through a mixed design
2022
Digital competence is not only a desirable skill for any citizen, but also a responsibility for the training of future teachers. Using a mixed methodology combining a questionnaire based on the Common Framework for Digital Competence in Teaching and open items, this paper aims to analyse the level of digital competence of 230 future teachers (Primary and Secondary Education), as well as to explore possible differences based on some basic variables. A study is also carried out on the perceived level of digital competence and the true level of digital competence, exploring, finally, the perceptions of the uses of technology in the educational environment. The results show that the level of di…
How accurate are teachers and support specialists when judging students' literacy skills? Special educational service as an external factor influenci…
2022
The aim of the study was to examine the accuracy of Estonian teachers' and support specialists' judgements of students' spelling skills and reading fluency and to investigate the provision of special education services to students as a factor influencing teachers' judgements. The sample included 11 classroom teachers, 8 support specialists, and 187 third-grade students. The judgements were collected using scales, and students' literacy skills were assessed using group and individual tests. The results indicated that judgements of reading fluency were less accurate than those of spelling skills. In addition, the provision of special education services influenced teachers' judgements, directi…
The RMQS-Biodiversity as a project of large-scale soil biodiversity monitoring in France
2022
International audience
Potencialidades del consorcio microbiano Curvularia kusanoi -Trichoderma pleuroticola como pretratamiento biológico para la degradación de fuentes fi…
2022
Objective. To evaluate the potentiality of the microbial consortium Curvularia kusanoi L7- Trichoderma pleuroticola as biological pretreatment of high fiber sources destined for animal production. Materials and methods. The Strains used where Curvularia kusanoi L7 and Trichoderma pleuroticola. The degradative potential was evaluated through the production kinetics of cellulolytic (endo-1,4-β-glucanase and exo-1,4-β-glucanase) and ligninolytics enzymes (laccase and peroxidase) in solid submerged fermentation of bran wheat and sugarcane bagasse. The growth of the co culture in plates was analyzed. The effect of the consortium on the carbon mineralization of raw wheat straw was determined and …
Transcriptome changes induced by Arbuscular mycorrhizal symbiosis in leaves of durum wheat (Triticum durum Desf.) promote higher salt tolerance
2022
AbstractThe salinity of soil is a relevant environmental problem around the world, with climate change raising its relevance, particularly in arid and semiarid areas. Arbuscular Mycorrhizal Fungi (AMF) positively affect plant growth and health by mitigating biotic and abiotic stresses, including salt stress. The mechanisms through which these benefits manifest are, however, still unclear. This work aimed to identify key genes involved in the response to salt stress induced by AMF using RNA-Seq analysis on durum wheat (Triticum turgidum L. subsp. durum Desf. Husn.). Five hundred sixty-three differentially expressed genes (DEGs), many of which involved in pathways related to plant stress resp…
Treatment of recurrent aphtous stomatitis: A systematic review
2022
Background: Recurrent Aphtous Stomatitis (RAS) is the most common process affecting the oral mucosa. It is painful, multifactorial and generally recurrent. The aim of this systematic review is to know the last treatment approaches and their effectivity.Material and Methods: we compared the outcome of different kind of treatments in terms of the improvement of the lesions, reduction of the size of those lesions and the time needed for their healing. Inclusion criteria were: clinical trials, articles written in English or Spanish and published less than 5 years ago.Results: we used the following keywords: treatment, aphtous stomatitis, canker sores; combined with Bool-ean operators AND y OR. …
Impact of abutment geometry on early implant marginal bone loss. A double‐blind, randomized, 6‐month clinical trial
2022
Objectives The objective of this study was to analyze the impact of the abutment width on early marginal bone loss (MBL). Material and Methods A balanced, randomized, double-blind clinical trial with two parallel experimental arms was conducted without a control group. The arms were “cylindrical” abutment and “concave” abutment. Eighty hexagonal internal connection implants, each with a diameter of 4 × 10 mm, were placed in healed mature bone. The main variable was the peri-implant tissue stability, which was measured as MBL at 8 weeks and 6 months. Results The final sample consisted of 77 implants that were placed in 25 patients. 38 (49.4%) were placed using the cylindrical abutment, and t…
Spatially segregated transmission of Co-occluded baculoviruses limits virus–virus interactions mediated by cellular coinfection during primary infect…
2022
This article belongs to the Section General Virology.
Bayesian inference of the fluctuating proton shape in DIS and hadronic collisions
2022
We determine the likelihood distribution for the model parameters describing the event-by-event fluctuating proton geometry at small $x$ by performing a Bayesian analysis within the Color Glass Condensate framework. The exclusive $\mathrm{J}/\psi$ production data from HERA is found to constrain the model parameters well, and we demonstrate that complementary constraints can be obtained from simulations of Pb+Pb collisions at the LHC.
The Narrative Medicine Approach in the Treatment of Diabetic Macular Edema: An Italian Experience.
2022
The study retraces the healthcare pathway of patients affected by diabetic macular edema (DME) through the direct voice of patients and caregivers by using a “patient journey” and narrative method approach. The mapping of the patient’s journey was developed by a multidisciplinary board of health professionals and involved four Italian retina centers. DME patients on intravitreal injection therapy and caregivers were interviewed according to the narrative medicine approach. Narratives were analyzed through a quali-quantitative tool, as set by the narrative medicine method. The study involved four specialized retina centers in Italy and collected a total of 106 narratives, 8…
Water reuse from wastewater treatment: The transition towards circular economy in the water sector
2022
Water is crucial for economic development since it interacts with the agricultural, production, and energy sec-tors. However, the increasing demand and climate change put pressure on water sources. This paper argued the necessity of using reclaimed water for irrigation within the scope of a circular economy. The barriers (i.e., technological and economic, institutional/regulatory, and social) to water reuse practices were revealed. Lessons on how to overcome the barriers were learned from good practices. The roadmaps adopted in the European Union for the transition towards the circular economy were reviewed. It has been observed that these roadmaps are generally on the circularity of solid …
Towards More Sustainable Sports: Analyzing the Travel Behavior of Adolescent Soccer Players in Southern Norway
2022
Mitigating climate change is a global challenge demanding effort from all sectors, and sports are no exception. While transportation is one of the key issues regarding sustainable sports, the methods by which children and adolescents get to practice have not received much attention. The objectives of this study were, therefore, to present how adolescents in Southern Norway travel to soccer practice and assess how the mode of transportation is related to sex, socioeconomic status, age, ethnicity, and distance from home to practice. Cross-sectional data were collected from 558 adolescent soccer players (398 boys and 190 girls) representing 30 different clubs from settlements of varying rurali…
Recycled aggregates derived from excavation materials — mechanical performance and identification of weak minerals
2022
AbstractThe present study investigates the mechanical performance of recycled aggregates derived from excavation materials (REM). REM is blended with different quantities of recycled phyllite materials (RPM) and is investigated by Los Angeles (LA) and micro-Deval (MD) tests. X-ray diffraction (XRD) and acid solubility test are performed on the pulverized fractions < 1.6 mm obtained from the LA and MD tests to assess the respective degree of fragmentation and wear of mineral components. The results of the materials in unblended conditions showed considerable difference between MD performance while similar performance was found for LA. Furthermore, about 40% of RPM was sufficient to blend …
Parental Self-Efficacy and Intra- and Extra-Familial Relationships
2022
AbstractRelationships are at the heart of well-being. Parental self-efficacy emerges as a powerful construct for understanding parenting and parent–child relationships. However, person-centered approaches that allow identification of different family-specific configurations of mothers’ and fathers’ parental self-efficacy and potential within-family discrepancies remain scarce. Families are more than the sums of their parts, and holistic approaches are needed to deepen our understanding of potential family-level accumulation of relationship well-being and vulnerability. A latent profile analysis of 249 families of preadolescents identified four family profiles of parental self-efficacy: (1) …
Assessing Climate Change Adaptation and Risk Management Programmes: Stakeholder Participation Process and Policy Implications for Transport, Energy a…
2022
Climate change is a critical sustainability challenge for islands and their main economic sectors. Rising sea levels, extreme temperatures, and drier conditions are the impacts with the most significant potential to amplify the economic damage on islands. However, their isolation and natural conditions bring about some leeway to respond to climate impacts on their terms. This paper aims to provide a local-level analysis and ranking of alternative adaptation pathways in an island context through the stakeholders’ lens. This study reviews the latest advancements in adaptation science and proposes a catalogue of adaptation and risk management options that feed a participatory assessment …
Elusive active faults in a low strain rate region (Sicily, Italy): Hints from a multidisciplinary land-to-sea approach
2022
Low Strain Rate regions (LSRrs), i.e., areas undergoing tectonic deformation at rates of 1 mm/yr or less, often host important cities and highly vulnerable anthropogenic assets, and due to their subdued topography and relatively infrequent seismicity, are often considered low seismic hazard areas. Despite this, infrequent but high-magnitude earthquakes in such regions suggest that identifying active structures in the LSRr is one of the primary challenges for both the scientific community and modern societies. In such regions, one of the main issues in identifying active faults is the lack of valuable outcrop data due to erosional/sedimentation rates overwhelming the fault deformation, causi…
A 2D-FEM Model of Nonlinear Ultrasound Propagation in Trans-cranial MRgFUS Technique
2022
Magnetic Resonance guided Focused Ultrasound (MRgFUS) is a non-invasive technique based on the thermal ablation of a target using high intensity focused ultrasound. MRgFUS treatment applied to brain is challenging due to the skull presence that attenuates ultrasound, leading to heating effects in bone region. In this study, we simulate trans-cranial nonlinear ultrasound propagation considering the detailed structure of bone tissue. We developed a 2D Finite Element (FE) model that mimics the propagation of focused ultrasound through skin, skull and brain tissue. The skull is represented as a three-layered system with two cortical tables packing a layer of trabecular bone. We assume that the …
Identification of the Gene Repertoire of the IMD Pathway and Expression of Antimicrobial Peptide Genes in Several Tissues and Hemolymph of the Cockro…
2022
This article belongs to the Special Issue Antimicrobial Peptides and Immunology.
More wood but less biodiversity in forests in Finland: a historical evaluation
2022
National forest inventories (NFI) in Finland provide empirical evidence for a marked increase in tree growth, total forest area, and total timber volume over the past century. Meanwhile, the assessments of threatened forest species and habitats indicate continuous degradation of biodiversity in Finnish forests. To shed light on this seeming paradox, we summarized the temporal patterns of forest characteristics (indicators) that have major influence on biodiversity, comparing the structure of current Finnish forests with natural and historical references. Using a variety of data sources, we estimated the proportion of area of old-growth forest and of deciduous-dominated forests, the density …
Empiric treatment of patients with sepsis and septic shock and place in therapy of cefiderocol: a systematic review and expert opinion statement
2022
AbstractCarbapenem-resistant Gram-negative bacteria are frequent causes of sepsis and septic shock in intensive care unit (ICU) and thus considered a public health threat. Until now, the best available therapies consist of combinations of preexisting or new antibiotics with β-lactamase inhibitors (either new or preexisting). Several mechanisms of resistance, especially those mediated by metallo-β-lactamases (MBL), are responsible for the inefficacy of these treatments, leaving an unmet medical need. Intravenous cefiderocol has been recently approved by the American Food and Drug Administration (FDA) and European Medicines Agency (EMA) for the treatment of complicated urinary tract infection…
An unusual case of chronic diarrhea: a case report
2022
Gastroenteropancreatic-neuroendocrine neoplasms or tumors (GEP-NEN or NETs) are rare tumors arising from the diffuse neuroendocrine system. This clinical case highlights the complexity of the diagnostic process and the difficulties in interpreting the examinations for this type of tumor, showing how the negativity of firstlevel examinations did not prevent from performing further investigations, in the presence of a suggestive clinical presentation. The search of similar cases in the published literature suggests that this represents an unusual presentation of a NET.
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19
2022
The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases of prospectively collected clinical data on people hospitalized with COVID-19. This dataset was compiled during the COVID-19 pandemic by a network of hospitals that collect data using the ISARIC-World Health Organization Clinical Characterization Protocol and data tools. The database includes data from more than 705,000 patients, collected in more than 60 countries and 1,500 centres worldwide. Patient data are available from acute hospital admissions with COVID-19 and outpatient follow-ups. The data include signs and symptoms, pre-existing como…
Glucose Metabolism Disorders: Challenges and Opportunities for Diagnosis and Treatment.
2022
Alterations of glucose metabolism are recognized as one of the most important risk factors for the development and complications of cardiometabolic diseases [...]
Long-Term COVID: Case Report and Methodological Proposals for Return to Work
2022
Almost two years after the beginning of the SARS-CoV-2 pandemic, the knowledge of which in the infectious and therapeutic spheres is constantly evolving, attention paid to the medicolegal aspects linked to this emergency phenomenon has mainly focused on the liability implications falling on healthcare personnel. With regard to the medicolegal assessment of the outcomes of COVID-19 illness, although it is a procedure that is commonly used, and although references in the assessment tables in force have been adhered to, a specific assessment protocol has not been standardized that takes into account, from an objective point of view, the degree of severity of the long-term residual outcomes and…
Distal Arthrogryposis type 5 in an Italian family due to an autosomal dominant gain-of-function mutation of the PIEZO2 gene
2022
Abstract Background Arthrogryposis multiplex congenita (AMC) is a group of clinically and etiologically heterogeneous conditions, characterized by prenatal onset contractures affecting two or more joints. Its incidence is about 1 in 3000 live births. AMC may be distinguished into amyoplasia, distal and syndromic arthrogryposis. Distal arthrogryposis (DA) predominantly affects hands and feet. It is currently divided into more than ten subtypes (DA1, DA2A/B, DA3–10), based on clinical manifestations, gene mutations and inheritance pattern. Among them, only a few patients with DA5 have been reported. It is associated to a gain-of-function pathogenic variant of the PIEZO2 gene, encoding for an …
The affective impact of sightseeing bus tour experiences:using Affective Events Theory (AET) to examine length-of-stay and electronic word-of-mouth
2022
This study investigates the key components and influences of positive affect and electronic word-of-mouth (eWOM) on tourist visits at two developing urban destinations, namely Birmingham, United Kingdom and Valencia, Spain. These two data collection sites yielded evidence gathered from 627 and 615 sightseeing bus tourists, respectively. Through the analytic lens of Affective Events Theory (AET), data was examined, and results verify the significant mediating role of affect in two regards: (1) tourists’ decision to extend their visits, and (2) eWOM of sightseeing bus tour experiences. The moderating role of past sightseeing experiences in these relationships was also supported by the data an…
How important is the role of iterative liver direct surgery in patients with hepatocellular carcinoma for a transplant center located in an area with…
2022
IntroductionHepatocellular carcinoma (HCC) accounts for nearly 90% of primary liver cancers, with estimates of over 1 million people affected by 2025. We aimed to explore the impacting role of an iterative surgical treatment approach in a cohort of HCC patients within the Milan criteria, associated with clinical risk factors for tumor recurrence (RHCC) after liver transplant (LT) and loco-regional therapies (LRT), as well as liver resection (LR) and/or microwave thermal ablation (MWTA).MethodsWe retrospectively analyzed our experience performed during an 8-year period between January 2013 and December 2021 in patients treated for HCC, focusing on describing the impact on preoperative end-st…
Biochar Particles Obtained from Agricultural Carob Waste as a Suitable Filler for Sustainable Biocomposite Formulations
2022
In the context of sustainable and circular economy, the recovery of biowaste for sustainable biocomposites formulation is a challenging issue. The aim of this work is to give a new life to agricultural carob waste after glucose extraction carried out by a local factory for carob candy production. A pyrolysis process was carried out on bio-waste to produce biofuel and, later, the solid residual fraction of pyrolysis process was used as interesting filler for biocomposites production. In this work, biochar particles (BC) as a pyrolysis product, after fuels recovery of organic biowaste, specifically, pyrolyzed carobs after glucose extraction, were added on poly(butylene-adipate-co-terephthalat…
'Trocios librorum parvi valoris' para reciclar
2022
El presente artículo presta atención a la reutilización, durante la Edad Media, de manuscritos deteriorados. Cuando un manuscrito se había deteriorado como consecuencia de un uso continuado, o de una conservación inadecuada, a menudo se reutilizaba, excepto en aquellos casos en que su contenido resultaba del interés de algún bibliófilo, que optaba por conservarlo. Se puede obtener información relativa a estos manuscritos en inventarios de libros y almonedas, donde se hace mención de su estado de conservación y de los detalles relativos a su venta en el mercado de segunda mano. The present article deals with the way manuscripts in poor condition were re-used during the Middle Ages. When a ma…
The Effect of Electronic Properties of Anodized and Hard Anodized Ti and Ti6Al4V on Their Reactivity in Simulated Body Fluid
2022
The electronic properties of barrier and porous layers on Ti and Ti6Al4V were studied. Barrier anodic oxides grown to 40 V on Ti and on Ti6Al4V are both n-type semiconductors with a band gap of 3.3 eV and 3.4 eV respectively, in agreement with the formation of amorphous TiO2. Anodizing to 200 V at 20 mA cm−2 in calcium acetate and β-glycerol phosphate disodium pentahydrate leads to the formation of Ca and P containing porous films with a photoelectrochemical behaviour dependent on the metallic substrate. A band gap of 3.2 eV and the flat band potential of −0.5 V vs Ag/AgCl were measured for the porous oxide on Ti, while optical transitions at 2.15 eV and a significantly more positive flat b…
Spray-Dried Cytisine-Loaded Matrices: Development of Transbuccal Sustained-Release Tablets as a Promising Tool in Smoking Cessation Therapy
2022
Cytisine (CYT) has emerged as a promising molecule to treat nicotine addiction, since it acts as a partial agonist of nicotinic acetylcholine receptors. However, its unfavorable pharmacokinetic properties lead to multiple administrations per day, reducing the patient’s compliance and increasing the side effects. To overcome these drawbacks, CYT buccal administration is here proposed. Firstly, CYT stability in the buccal environment was assessed and its intrinsic ability to permeate/penetrate the tissue was determined by applying CYT solutions at increasing concentrations. Furthermore, a spray-drying method was selected and optimized as it is an eco-friendly, easily scalable and effective te…
Climate change engenders a better Early Warning System development across Sub-Saharan Africa: The malaria case
2022
It is expected that diseases are likely to spread to newer areas, and high-income countries may experience some illnesses that may have been restricted to low or middle-income countries. In addition, following the Intergovernmental Panel on Climate Change, the present study noted that climate change is likely to have many effects on the spatial and temporal distribution of malaria in many Sub-Saharan African countries. This study examines climate change effects on the geographical distribution of malaria occurrence and how extreme climatic events may perhaps be determining factors in the range of vectors for human diseases in SSA in the nearest future. Here, the study appraisals the symbiot…
Entropy and institutional theory
2022
PurposeOnce introduced and conceptualized as a factor that causes erosion and decay of social institutions and subsequent deinstitutionalization, the notion of entropy is at odds with predictions of institutional isomorphism and seems to directly contradict the tendency toward ever-increasing institutionalization. The purpose of this paper is to offer a resolution of this theoretical inconsistency by revisiting the meaning of entropy and reconceptualizing institutionalization from an information-theoretic point of view.Design/methodology/approachIt is a theoretical paper that offers an information perspective on institutionalization.FindingsA mistaken understanding of the nature and role of…