Search results for " Computer-Assisted"
showing 10 items of 1033 documents
Fast Estimation of Diffusion Tensors under Rician noise by the EM algorithm
2016
Diffusion tensor imaging (DTI) is widely used to characterize, in vivo, the white matter of the central nerve system (CNS). This biological tissue contains much anatomic, structural and orientational information of fibers in human brain. Spectral data from the displacement distribution of water molecules located in the brain tissue are collected by a magnetic resonance scanner and acquired in the Fourier domain. After the Fourier inversion, the noise distribution is Gaussian in both real and imaginary parts and, as a consequence, the recorded magnitude data are corrupted by Rician noise. Statistical estimation of diffusion leads a non-linear regression problem. In this paper, we present a f…
Label swapper device for spectral amplitude coded optical packet networks monolithically integrated on InP
2011
In this paper the design, fabrication and experimental characterization of an spectral amplitude coded (SAC) optical label swapper monolithically integrated on Indium Phosphide (InP) is presented. The device has a footprint of 4.8x1.5 mm 2 and is able to perform label swapping operations required in SAC at a speed of 155 Mbps. The device was manufactured in InP using a multiple purpose generic integration scheme. Compared to previous SAC label swapper demonstrations, using discrete component assembly, this label swapper chip operates two order of magnitudes faster. © 2011 Optical Society of America.
Automatable sample fabrication process for pump-probe X-ray holographic imaging
2014
Soft X-ray holography is a recently developed imaging technique with sub-50 nm spatial resolution. Key advantages of this technique are magnetic and elemental sensitivity, compatibility with imaging at free electron laser facilities, and immunity to in-situ sample excitations and sample drift, which enables the reliable detection of relative changes between two images with a precision of a few nanometers. In X-ray holography, the main part of the experimental setup is integrated in the sample, which consequently requires a large number of fabrication steps. Here we present a generic design and an automatable fabrication process for samples suitable, and optimized for, efficient high resolut…
Phenotypic analysis of adults and eggs of Fasciola hepatica by computer image analysis system
2005
AbstractKnowledge of the morphological phenotypes of the liver fluke Fasciola hepatica (Trematoda: Digenea) is analysed. The influence of parasite age on its dimensions, the adult fluke growth model, variation in a biometric variable versus time, and variation in a biometric variable versus another biometric variable (allometric model) are revised. The most useful allometric model appears to be (y2m]#x2212;y2)/y2=c [(y1m−y1)/y1]b, where y1=body area or body length, y2=one of the measurements analysed, y1m, y2m=maximum values towards which y1 and y2, respectively, tend, and c, b=constants. A method based on material standardization, the measurement proposal and allometric analysis is detaile…
Colourimetric image analysis as a diagnostic tool in female genital schistosomiasis
2015
Female genital schistosomiasis (FGS) is a highly prevalent waterborne disease in some of the poorest areas of sub-Saharan Africa. Reliable and affordable diagnostics are unavailable. We explored colourimetric image analysis to identify the characteristic, yellow lesions caused by FGS. We found that the method may yield a sensitivity of 83% and a specificity of 73% in colposcopic images. The accuracy was also explored in images of simulated inferior quality, to assess the possibility of implementing such a method in simple, electronic devices. This represents the first step towards developing a safe and affordable aid in clinical diagnosis, allowing for a point-of-care approach.
Diffractive optics for quasi-direct space-to-time pulse shaping.
2008
The strong chromatic behavior associated with a conventional diffractive lens is fully exploited to propose a novel optical device for pulse shaping in the femtosecond regime. This device consists of two optical elements: a spatially patterned circularly symmetric mask and a kinoform diffractive lens, which are facing each other. The system performs a mapping between the spatial position of the masking function expressed in the squared radial coordinate and the temporal position in the output waveform. This space-to-time conversion occurs at the chromatic focus of the diffractive lens, and makes it possible to tailor the output central wavelength along the axial location of the output point…
Formation of ultrashort triangular pulses in optical fibers
2014
Specialty shape ultrashort optical pulses, and triangular pulses in particular, are of great interest in optical signal processing. Compact fiber-based techniques for producing the special pulse waveforms from Gaussian or secant pulses delivered by modern ultrafast lasers are in demand in telecommunications. Using the nonlinear Schr¨odinger equation in an extended form the transformation of ultrashort pulses in a fiber towards triangular shape is characterized by the misfit parameter under variety of incident pulse shapes, energies, and chirps. It is shown that short (1-2 m) conventional single mode fiber can be used for triangular pulse formation in the steady-state regime without any pre-…
Femtosecond parabolic pulse shaping in normally dispersive optical fibers
2013
Formation of parabolic pulses at femtosecond time scale by means of passive nonlinear reshaping in normally dispersive optical fibers is analyzed. Two approaches are examined and compared: the parabolic waveform formation in transient propagation regime and parabolic waveform formation in the steady-state propagation regime. It is found that both approaches could produce parabolic pulses as short as few hundred femtoseconds applying commercially available fibers, specially designed all-normal dispersion photonic crystal fiber and modern femtosecond lasers for pumping. The ranges of parameters providing parabolic pulse formation at the femtosecond time scale are found depending on the initia…
Atypical perceptual narrowing in prematurely born infants is associated with compromised language acquisition at 2 years of age
2010
Abstract Background Early auditory experiences are a prerequisite for speech and language acquisition. In healthy children, phoneme discrimination abilities improve for native and degrade for unfamiliar, socially irrelevant phoneme contrasts between 6 and 12 months of age as the brain tunes itself to, and specializes in the native spoken language. This process is known as perceptual narrowing, and has been found to predict normal native language acquisition. Prematurely born infants are known to be at an elevated risk for later language problems, but it remains unclear whether these problems relate to early perceptual narrowing. To address this question, we investigated early neurophysiolog…
On Unsupervised Methods for Medical Image Segmentation: Investigating Classic Approaches in Breast Cancer DCE-MRI
2021
Unsupervised segmentation techniques, which do not require labeled data for training and can be more easily integrated into the clinical routine, represent a valid solution especially from a clinical feasibility perspective. Indeed, large-scale annotated datasets are not always available, undermining their immediate implementation and use in the clinic. Breast cancer is the most common cause of cancer death in women worldwide. In this study, breast lesion delineation in Dynamic Contrast Enhanced MRI (DCE-MRI) series was addressed by means of four popular unsupervised segmentation approaches: Split-and-Merge combined with Region Growing (SMRG), k-means, Fuzzy C-Means (FCM), and spatial FCM (…