Search results for " Library"

Publishing studies

2015

In some parts of the world, Publishing Studies are a fairly well-established field of research as well as of higher education. Not least since this is not so much the case in continental Europe, the Publishing Studies community increasingly sees a more elaborated self-concept as an important prerequisite for a prosperous further development of the field in research as well as in teaching. This paper starts off by relating the question for an advanced self-concept of Publishing Studies to the question what criteria have to be fulfilled to call a field (like Publishing Studies) a scholarly discipline. As the second source for the possible formation of a more elaborate self-concept, the paper …

De la videopolítica a la ciberpolítica: debate entre candidatos y televisiones en cinco elecciones presidenciales

2019

Los medios de comunicacion se convierten en actores politicos tambien en el espacio digital, en donde su informacion construye una agenda que se relaciona con candidatos y ciudadanos. La presente investigacion analiza las cuentas oficiales de Twitter de las dos principales televisiones en Argentina, Peru, Ecuador, Honduras y Chile durante 28 dias, que corresponden con los procesos electorales y campanas de las elecciones presidenciales celebradas en America Latina en el periodo 2015-2017. A traves del estudio de 16.359 emisiones mediante herramientas como Python Twint, NVivo y SPSS, se correlacionan las tematicas mas relevantes en cada proceso electoral, poniendolas en discusion con las age…

ISOLATION OF RAT CDNA CLONES CODING FOR THE AUTOANTIGEN SS-B/LA - DETECTION OF SPECIES-SPECIFIC VARIATIONS

1993

Clones of cDNA coding for the autoantigen La (or SS-B) were isolated from a library made from rat liver. A comparison of the rat La cDNA (encoding from nt 38 to 1281 for rat La protein) with the sequences known for human and bovine La protein resulted in the identification of species-specific inserts. The inserts seem to be the result of multiplication of flanking sequences during evolution. In addition to these variations, we observed that rat La cDNAs exhibit non-canonical polyadenylation sites. Finally, a databank search resulted in the identification of a DNA sequence originally termed as TAG or TSG20X (GenBank accession No. X61893) which represents the C terminus of mouse La/SS-B prote…

CRISPR-Cas12a-Based Detection of SARS-CoV-2 Harboring the E484K Mutation

2021

The novel respiratory virus SARS-CoV-2 is rapidly evolving across the world with the potential of increasing its transmission and the induced disease. Here, we applied the CRISPR-Cas12a system to detect, without the need of sequencing, SARS-CoV-2 genomes harboring the E484K mutation, first identified in the Beta variant and catalogued as an escape mutation. The E484K mutation creates a canonical protospacer adjacent motif for Cas12a recognition in the resulting DNA amplicon, which was exploited to obtain a differential readout. We analyzed a series of fecal samples from hospitalized patients in Valencia (Spain), finding one infection with SARS-CoV-2 harboring the E484K mutation, which was t…

Transforming of the librarian role in the University of Latvia research librarian function

2015

Predictive validity of the GOSLON Yardstick index in patients with unilateral cleft lip and palate: A systematic review

2017

Among the various indices developed for measuring the results of treatment in patients born with unilateral cleft lip and palate (UCLP), the GOSLON Yardstick index is the most widely used to assess the efficacy of treatment and treatment outcomes, which in UCLP cases are closely linked to jaw growth. The aim of this study was to conduct a systematic review to validate the predictability of growth using the GOSLON Yardstick in patients born with UCLP. A systematic literature review was conducted in four Internet databases: Medline, Cochrane Library, Scopus and Embase, complemented by a manual search and a further search in the databases of the leading journals that focus on this topic. An el…

Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

2007

Abstract Background The melanocortin (MC) receptors have a key role in regulating body weight and pigmentation. They belong to the rhodopsin family of G protein-coupled receptors (GPCRs). The purpose of this study was to identify ancestral MC receptors in agnathan, river lamprey. Results We report cloning of two MC receptors from river lamprey. The lamprey receptors, designated MCa and MCb, showed orthology to the MC1 and MC4 receptor subtypes, respectively. The molecular clock analysis suggested that lamprey MC receptor genes were not duplicated recently and diverged from each other more than 400 MYR ago. Expression and pharmacological characterization showed that the lamprey MCa receptor …

Proposal for the Reengineering of Processes in the Management of Information and Communication Technology

2019

This article describes the strategies implemented in the improvement of the processes in the management of information and communication technology (ICT) on the “Universidad Nacional de Loja” carried out by the “Unidad de Telecomunicaciones e Informacion” (UTI). First, the analysis of the processes carried out in the management of ICT is narrated. Subsequently, the experiences and best practices of information technology management implemented are described, considering the processes recommended by the Technology Infrastructure Library of Information (ITIL v3). Finally, the results obtained from the process of reengineering in ICT management carried out by the UTI are shown, using free soft…

Strategising IT service management through ITIL implementation: model and empirical test

2015

Research on the Information Technology Infrastructure Library (ITIL) lacks appropriate theories and models that capture the distinct characteristics and implications of the ITIL implementation practice. The purpose of this study is to close this gap. Based on a literature review, we develop and empirically validate a theoretical model: the ITIL Implementation Project Model. The model includes significant antecedents, which provide a foundation upon which an effective ITIL implementation project can be built, as well as the pertinent effects of implementing ITIL. The results contribute to the current research stream on the strategising of IT service management as well as to an improved under…

Políticas públicas de lectura e investigación. El diseño del Plan Valenciano de Lectura

2017

Para determinar con exactitud qué acciones deben ser consideradas prioritarias en el diseño de las políticas públicas de lectura es necesario contar, en primer lugar, con equipos de investigación que aporten datos concretos que aseguren su éxito; en segundo lugar, con metodologías para su diseño, seguimiento y evaluación; en tercer lugar, con protocolos para su mejora y, finalmente, con indicadores para la medición de los objetivos y los resultados. Este artículo resume y reflexiona sobre los retos que enfrentan las políticas de lectura a partir de la revisión de las principales investigaciones e informes institucionales sobre el tema y describe el proceso de trabajo, las metodologías utili…