Search results for " Mark"
showing 10 items of 4118 documents
Cardiorenal syndrome: the role of new biochemical markers
2012
Cardiorenal syndrome is a pathophysiological heart and kidney disorder, in which acute or chronic dysfunction of one organ induces a damage in the other. It's a syndrome more and more often encountered in clinical practice and this implies the need to recognize the syndrome through biochemical markers with a good sensitivity and specificity, since its earliest stages in order to optimize therapy. In addition to widely validated biomarkers, such as BNP, pro BNP, creatinine, GFR and cystatin C, other promising molecules are available, like NGAL (neutrophil gelatinase-associated lipocalin, KIM-1 (kidney injury molecule-1), MCP-1 (monocyte chemotactic peptide), Netrin-1, interleuchin 18 and NAG…
Gli effetti extraglicemici di liraglutide: Focus sui marker cardiometabolici
2016
The purpose of innovative therapeutic approaches for type 2 diabetes mellitus is to customize the antidiabetic treatment to each patient's need, in order to intensify glucose-lowering effects without hypoglycemia, reduce adverse events, and prevent cardiovascular events. Glucagon-like peptide 1 (GLP-1) analogues are effective drugs in the treatment of type 2 diabetes, and they also seem to have beneficial effects on several risk factors for cardiovascular disease, leading to cardiovascular risk reduction independent of hypoglycemic effects. Among these new drugs, liraglutide, a GLP-1 analogue with a homology of 97% to native GLP-1, exerts an effect on body weight, lipid parameters, blood pr…
Consumer attitude toward using smart shopping carts: a comparative analysis of Italian and Croatian consumer attitudes
2016
This paper aims to explore consumer attitudes toward using smart shopping cart, considering country of origin, gender, age, and intentions to use smart shopping carts while purchasing. Moreover, it investigates the influence of extracted factors on consumers' attitudes toward using smart shopping carts and the users' levels of digital competence. The data was collected through survey questionnaires using a purposive sample of 313 Croatian and Italian respondents. To this end, we applied statistical methodologies such as binary logistic regression, factor analysis, and analysis of variance. We found that, compared with Croatians, Italian respondents have a more positive attitude toward using…
Why do People Attend Sport Events at Mature Tourist Destinations? An Analysis of Visitors’ Motivation to Attend the Windsurf World Cup on Sylt
2016
Abstract Introduction. Sport events have become a popular tool for the marketing of tourist destinations. In this regard, it has to be kept in mind that the effects events can generate for destinations largely depend on the motivation of the attendees. Building on this insight, the aim of this paper is to compare the motivational structures of two types of visitors (primary purpose event visitors and casual visitors) to the German island of Sylt during a Windsurf World Cup. This event-destination combination was chosen because it represents the tendency for popular tourist resorts to use small-scale sport events in their marketing efforts. Material and methods. The research was conducted us…
Prediction and Control: The Specific Role of Business Angels in the Investment Process
2019
International audience; Entrepreneurs and related investors (business angels and venture capitalists) rely on different types of rationalities. Extant research suggests that conflicts resulting from misunderstanding can emerge between entrepreneurs and investors when they adopt different rationalities but must switch those rationalities because of the maturity of their ventures and the degree of uncertainty they face. Relying on three in-depth case studies, this research contributes to both entrepreneurship and effectuation literature by emphasizing the specific role of business angels in helping entrepreneurs switch rationalities when necessary to attract funding resources from venture cap…
CAUSE RELATED MARKETING – TRUE HEART-FELT CORPORATE BENEVOLENCE?
2011
Nowadays, globally, consumers’ expectations have reached a new high, as they expect companies to act responsibly in changing the world. More than often these expectations are not met solely out of the kindness and generosity of corporations, but they are mixed in with corporate social responsibility programs and cause-related marketing. Consumers want more of the products and services they buy to support worthy social and environmental issues.
Developing successful cause-related marketing campaigns through social-networks the moderating role of users’ age
2018
This paper joins two streams of literature: caused-related marketing and viral advertising. Three main objectives guide our work: (i) to test whether a transfer of attitudes occurs in a viral cause...
Segmentando el mercado de internautas atendiendo a su nivel de afinidad: (I)fuerte, (II)medio y (III)débil
2017
Esta investigación pretende confrontar el Marketing con Causa con el Marketing de Afinidad. Para ello se descompone la audiencia de una campaña de Marketing con Causa viral en segmentos de internautas con distinto nivel de afinidad: i) fuerte (con experiencia previa de marca y de causa); ii) medio (con experiencia previa o de marca o de causa); iii) débil (sin experiencia previa ni de marca ni de causa). El objetivo es justificar la utilidad de este criterio como vía para optimizar el resultado de la comunicación segmentada. Con dicho fin, se ha estudiado un caso real planteado de forma experimental midiendo las actitudes de una muestra de 276 internautas antes y después de visualizar un sp…
Sociālo mediju ietekmētāju nozīme digitālajā mārketingā
2021
Šī pētījuma mērķis ir izprast sociālo mediju ietekmētāju nozīmi digitālā mārketinga produktos un pakalpojumos mūsdienu pasaulē. Apkopojiet atbilstošas zināšanas par sociālo mediju mārketingu un ietekmētājiem, kā arī sociālo mediju ietekmētāju lomu dažādu zīmolu un pakalpojumu veiksmīgā mārketingā. Izpētiet sociālo mediju ietekmētāju lomu zīmola attīstībā klientu interesēs. Sagatavotā aptauja galvenokārt sastāv no 15 jautājumiem ar atbilžu variantiem. Visi jautājumi tika izstrādāti, izmantojot kvantitatīvās analīzes metodes. Mans galvenais mērķis, veidojot anketu, ir efektīvi apkopot atsauksmes. Šīs analīzes pierāda, ka sociālo mediju ietekmētājiem ir milzīga ietekme uz mūsdienu tirgu, īpaši…
Exosomes as Intercellular Signaling Organelles Involved in Health and Disease: Basic Science and Clinical Applications
2013
Cell to cell communication is essential for the coordination and proper organization of different cell types in multicellular systems. Cells exchange information through a multitude of mechanisms such as secreted growth factors and chemokines, small molecules (peptides, ions, bioactive lipids and nucleotides), cell-cell contact and the secretion of extracellular matrix components. Over the last few years, however, a considerable amount of experimental evidence has demonstrated the occurrence of a sophisticated method of cell communication based on the release of specialized membranous nano-sized vesicles termed exosomes. Exosome biogenesis involves the endosomal compartment, the multivesicu…