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showing 10 items of 5003 documents

Carbohydrate-deficient transferrin (CDT) and HDL cholesterol (HDL) are highly correlated in male alcohol dependent patients.

2000

Background: Serum levels of total HDL cholesterol (HDL) are reportedly influenced by recent alcohol intake. We examined the correlation between HDL cholesterol and widely used markers of excessive alcohol intake, such as carbohydrate-deficient transferrin (CDT), γ-glutamyl-transferase (GGT), or mean corpuscular volume of erythrocytes (MCV), of which CDT is thought to be the most specific. Methods: Several serological markers [i.e., CDT, GGT, aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), MCV, and HDL] were determined in 100 actively drinking male patients with alcohol dependence (DSM-IV) and in 27 non-alcohol-dependent controls, according to routine procedures. Spearman…

AdultErythrocyte IndicesMalemedicine.medical_specialtyAdolescentCarbohydrate deficient transferrinMedicine (miscellaneous)AlcoholToxicologyStatistics Nonparametricchemistry.chemical_compoundInternal medicinemedicineHumansMean corpuscular volumeAgedchemistry.chemical_classificationEthanolmedicine.diagnostic_testbusiness.industryCholesterolAlcohol dependenceCholesterol HDLTransferringamma-GlutamyltransferaseMiddle AgedPsychiatry and Mental healthAlcoholismEndocrinologychemistryTransferrinToxicitylipids (amino acids peptides and proteins)businessBiomarkersAlcoholism, clinical and experimental research
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Vitamin B12 and hepatic enzyme serum levels correlate in male alcohol-dependent patients.

2001

- Vitamin B12 serum levels and markers for alcohol consumption were determined in 80 male alcohol-dependent patients. Spearman correlation coefficients (r(S)) were calculated. Significant positive correlations between vitamin B12 and hepatic enzyme values were found (gamma-glutamyltransferase: r(S) = 0.58; alanine aminotransferase: r(S) = 0.43; aspartate aminotransferase: r(S) = 0.47; glutamate dehydrogenase: r(S) = 0.43; all P:0.001). Therefore, for a proper interpretation of vitamin B12 levels, it may be clinically relevant to take markers of hepatocellular damage into account.

AdultErythrocyte IndicesMalemedicine.medical_specialtyCarbohydrate deficient transferrinAspartate transaminaseStatistics NonparametricGlutamate DehydrogenaseInternal medicineBlood plasmamedicineHumansCyanocobalaminVitamin B12Aspartate AminotransferasesLiver Diseases AlcoholicRetrospective StudiesbiologyGlutamate dehydrogenaseTransferrinnutritional and metabolic diseasesAlanine TransaminaseGeneral Medicinegamma-GlutamyltransferaseMiddle AgedAlcoholismVitamin B 12EndocrinologyAlanine transaminaseLiverToxicitybiology.proteinBiomarkersAlcohol and alcoholism (Oxford, Oxfordshire)
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Clinical practices to promote sleep in the ICU: A multinational survey

2018

PURPOSE: To describe sleep assessment and strategies to promote sleep in adult ICUs in ten countries.METHODS: Multicenter, self-administered survey sent to nurse managers.RESULTS: Response rate was 66% with 522 ICUs providing data. 'Lying quietly with closed eyes' was the characteristic most frequently perceived as indicative of sleep by >60% of responding ICUs in all countries except Italy. Few ICUs (9%) had a protocol for sleep management or used sleep questionnaires (1%). Compared to ICUs in Northern Europe, those in central Europe were more likely to have a sleep promoting protocol (p < 0.001), and to want to implement a protocol (p < 0.001). In >80% of responding ICUs, the …

AdultFreedommedicine.medical_specialtyInternationalityhealth care facilities manpower and servicesPsychological intervention03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesIntensive careSleep ProtocolsHumansMedicine030212 general & internal medicineMultivariable modelGeneral NursingResponse rate (survey)business.industrySleep assessment030208 emergency & critical care medicineSleep in non-human animalsIntensive Care UnitsEmergency medicineClosed eyesNurse-Patient RelationsSleepbusinessInternational journal of nursing studies
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Dynamic contrast-enhanced myocardial perfusion imaging using saturation-prepared TrueFISP.

2002

Purpose To develop and test a saturation-recovery TrueFISP (SR-TrueFISP) pulse sequence for first-pass myocardial perfusion imaging. Materials and Methods First-pass magnetic resonance imaging (MRI) of Gd-DTPA (2 mL) kinetics in the heart was performed using an SR-TrueFISP pulse sequence (TR/TE/α = 2.6 msec/1.4 msec/55°) with saturation preparation TD = 30 msec before the TrueFISP readout. Measurements were also performed with a conventional saturation-recovery TurboFLASH (SRTF) pulse sequence for comparison. Results SR-TrueFISP images were of excellent quality and demonstrated contrast agent wash-in more clearly than SRTF images. The signal increase in myocardium was higher in SR-TrueFISP …

AdultGadolinium DTPAMaterials scienceImage qualityContrast MediaImage processingStatistics NonparametricMyocardial perfusion imagingNuclear magnetic resonancePrecontrastCoronary CirculationmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingImage resolutionmedicine.diagnostic_testbusiness.industryPhantoms ImagingMicrocirculationMagnetic resonance imagingPulse sequenceMagnetic Resonance ImagingNuclear medicinebusinessPerfusionJournal of magnetic resonance imaging : JMRI
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Serology in adults with celiac disease: limited accuracy in patients with mild histological lesions.

2010

Celiac disease (CD) is a gluten-triggered enteropathy, presenting with insidious clinical patterns. It can occasionally be diagnosed in asymptomatic subjects. Our aim was to define the relationship among symptoms at diagnosis, serological markers [tissue transglutaminase antibodies (tTGA), anti-endomysium antibodies (EMA) anti-actin antibodies (AAA)] and degree of mucosal damage. A total of 68 consecutive adult patients with CD were enrolled. Intestinal biopsies were scored according to the Marsh classification modified by Oberhuber: I–II minimal lesions or absent villous atrophy; IIIA partial villous atrophy; IIIB–C total villous atrophy (TVA). HLA-typing was done for all patients. No asso…

AdultGenetic MarkersMalePathologymedicine.medical_specialtyAdolescentTissue transglutaminaseEnzyme-Linked Immunosorbent AssayDiseaseSeverity of Illness IndexAsymptomaticStatistics NonparametricSerologyYoung AdultInternal MedicinemedicineHumansEnteropathyIn patientProspective StudiesIntestinal MucosaVillous atrophyAgedAged 80 and overbiologybusiness.industryMiddle Agedmedicine.diseaseImmunoglobulin AItalyEmergency Medicinebiology.proteinFemaleAntibodymedicine.symptombusinessceliac disease
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Effects of an ultra-long-distance (1000 km) race on lipid metabolism

1989

The influence was examined of ultra-long-distance running (1000 km race lasting 20 days) on changes in serum lipids. The 110 participants received two types of diet, a conventional Western diet and a wholesome vegetarian diet. Of the 55 finishers the serum concentration of total cholesterol, low density lipoprotein (LDL)-cholesterol, apolipoprotein B and triglycerides decreased significantly during the first 8 days of the run, but rose again towards the end of the race without reaching pre-race levels. The high density lipoprotein (HDL)-cholesterol increased initially but decreased in the final days of the run. The values for apolipoprotein A-I were not correlated with HDL-cholesterol. The …

AdultGlycerolMalemedicine.medical_specialtyApolipoprotein BPhysiologyBlood lipidsFatty Acids NonesterifiedRunningchemistry.chemical_compoundHigh-density lipoproteinPhysiology (medical)Internal medicinemedicineHumansOrthopedics and Sports MedicineApolipoproteins ATriglyceridesAgedApolipoproteins BbiologyTriglycerideCholesterolCholesterol HDLPublic Health Environmental and Occupational HealthLipid metabolismGeneral MedicineMiddle AgedLipid MetabolismDietCholesterolEndocrinologychemistryLow-density lipoproteinbiology.proteinFemalelipids (amino acids peptides and proteins)LipoproteinEuropean Journal of Applied Physiology and Occupational Physiology
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Neural-level associations of non-verbal pragmatic comprehension in young Finnish autistic adults

2021

This video-based study examines the pragmatic non-verbal comprehension skills and corresponding neural-level findings in young Finnish autistic adults, and controls. Items from the Assessment Battery of Communication (ABaCo) were chosen to evaluate the comprehension of non-verbal communication. Inter-subject correlation (ISC) analysis of the functional magnetic resonance imaging data was used to reveal the synchrony of brain activation across participants during the viewing of pragmatically complex scenes of ABaCo videos. The results showed a significant difference between the ISC maps of the autistic and control groups in tasks involving the comprehension of non-verbal communication, there…

AdultHealth (social science)non-verbalEpidemiologyRC955-962fMRsanaton viestintävideobehavioral disciplines and activitiesDevelopmental psychology03 medical and health sciencesNonverbal communicationtoiminnallinen magneettikuvaus0302 clinical medicineBehavior TherapyautismiArctic medicine. Tropical medicineautistic adultsHumansOriginal Research Article030212 general & internal medicineAutistic DisorderAutism spectrum; autistic adults; fMRI; non-verbal; pragmatics; videoFinland030505 public healthnonverbalfMRIPublic Health Environmental and Occupational Healthautismikirjon häiriötGeneral MedicinePragmaticsMagnetic Resonance ImagingComprehensionpragmatiikkaAutism spectrumautism spectrumComprehension0305 other medical sciencePsychologypragmaticsResearch ArticleInternational Journal of Circumpolar Health
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Supraventricular arrhythmias in noncompaction of left ventricle: Is this a frequent complication?

2008

Background: Isolated left ventricular noncompaction is the result of incomplete myocardial morphogenesis, leading to persistence of the embryonic myocardium. The condition is recognised by an excessively prominent trabecular meshwork and deep intertrabecular recesses of the left ventricle. Whether these intertrabecular recesses are a favorable substrate for supraventricular arrhythmias is unclear, even if the incidence of chronic heart failure seems to be high. Results: We evaluated a continuous series of 238 patients affected by noncompaction. In 4 cases the patients reported palpitations and in 4 an episode of syncope. Periodic holter monitoring was performed every 6 months for 4 years. O…

AdultHeart Defects CongenitalMaleRegistriemedicine.medical_specialtyIsolated left ventricular noncompactionSupraventricular arrhythmiasPalpitation syncopeElectrocardiographyRisk FactorsRetrospective StudieInternal medicinemedicinePalpitationsTachycardia SupraventricularHumansRegistriescardiovascular diseasesRetrospective StudiesAgedAged 80 and overSupraventricular arrhythmiabusiness.industryIsolated left ventricular noncompaction; Supraventricular arrhythmias; Atrial fibrillation; Palpitation syncopeRisk FactorAtrial fibrillationMiddle Agedmedicine.diseaseAtrial fibrillationSupraventricular arrhythmiaSurgerymedicine.anatomical_structureItalyVentricleHeart failureCirculatory systemCardiologycardiovascular systemLeft ventricular noncompactionFemaleSupraventricular tachycardiamedicine.symptombusinessCardiology and Cardiovascular MedicineHuman
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Ventricular tachycardia in non-compaction of left ventricle: Is this a frequent complication?

2007

Background: Isolated left ventricular non-compaction is the result of incomplete myocardial morphogenesis, leading to persistence of the embryonic myocardium. The condition is recognized by an excessively prominent trabecular meshwork and deep intertrabecular recesses of the left ventricle. Whether these intertrabecular recesses are a favorable substrate for ventricular arrhythmias is unclear. Some reports have found that the fatal ventricular arrhythmias may occur in approximately half of the patients. In this report we investigated about this association. Methods and Results: In total we evaluated a continuous series of 238 patients affected by non-compaction. Periodic Holter monitoring w…

AdultHeart Defects CongenitalMalemedicine.medical_specialtyVentricular tachycardiaElectrocardiographyVentricular arrhythmiasIsolated left ventricular non-compaction; Malignant; Ventricular arrhythmias; Ventricular tachycardiaRisk FactorsInternal medicinemedicineHumansRegistriesisolated left ventricular non-compaction ventricular arrhythmias ventricular tachycardia malignantcardiovascular diseasesRisk factorRetrospective StudiesMALIGNANCYIsolated left ventricular non-compactionMalignantbusiness.industryVentricular tachycardiaGeneral MedicineMiddle Agedmedicine.diseasemedicine.anatomical_structureItalyVentricleAnesthesiaChild PreschoolVentricular fibrillationCardiologyTachycardia Ventricularcardiovascular systemFemaleTrabecular meshworkCardiology and Cardiovascular MedicinebusinessComplicationHolter monitoringVENTRICULAR ARRHYTHMIAS.
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The short‐term effect of levocetirizine on quality of life, stress, and depression in itchy psoriasis patients

2019

AdultHistamine H1 Antagonists Non-Sedatingmedicine.medical_specialtyMEDLINEDermatologyLevocetirizineQuality of life (healthcare)Surveys and QuestionnairesInternal medicinePsoriasisHumansPsoriasisMedicineTerm effectDepression (differential diagnoses)Depressionbusiness.industryPruritusGeneral MedicineMiddle AgedHistamine H1 Antagonistsmedicine.diseaseCetirizineQuality of LifebusinessStress Psychologicalmedicine.drugDermatologic Therapy
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