Search results for "ARCHITECTURE"

The genetic architecture of sexually selected traits in two natural populations of Drosophila montana

2015

The work was supported by the National Environment Research Council (grant NE/E015255/1 to MGR and RKB) and the Academy of Finland (project 132619 to AH). We investigated the genetic architecture of courtship song and cuticular hydrocarbon traits in two phygenetically distinct populations of Drosophila montana. To study natural variation in these two important traits, we analysed within-population crosses among individuals sampled from the wild. Hence, the genetic variation analysed should represent that available for natural and sexual selection to act upon. In contrast to previous between-population crosses in this species, no major quantitative trait loci (QTLs) were detected, perhaps be…

Assessing Reading Skills with a Computer-aided Set of Tests Based on the Dual-route Theory of Reading

1993

Changing the General Factor of Personality and the c-fos Gene Expression with Methylphenidate and Self-Regulation Therapy

2012

[EN] A deepening in the biological nature of the general factor of personality (GFP) is suggested: the activation level of the stress system is here represented by the gene expression of c-fos. The results of a single case experimental design are reported. A model of four coupled differential equations that explains the human personality dynamics as a consequence of a single stimulant drug intake has been fitted to psychological and biological experimental data. The stimulant-drug conditioning and its adaptation to the considered mathematical model is also studied for both kinds of measures. The dynamics of the cfos expression presents a similar pattern to the dynamics of the psychological …

Can't simply roll it out: Evaluating a real-world virtual reality intervention to reduce driving under the influence.

2020

Driving under the influence (DUI) increases the risk of crashes. Emerging technologies, such as virtual reality (VR), represent potentially powerful and attractive tools for the prevention of risky behaviours, such as DUI. Therefore, they are embraced in prevention efforts with VR interventions primed to grow in popularity in near future. However, little is known about the actual effectiveness of such DUI-targeting VR interventions. To help fill the knowledge gap, this study explored the effects of one VR intervention as delivered in the real world. Using pre and post test design, including an intervention group (n = 98) and a control group (n = 39), the intervention evaluation examined you…

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

2013

The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growth factors. Although little is known about the underlying genetics, growth variability during puberty correlates with adult risks for hormone-dependent cancer and adverse cardiometabolic health. The only gene so far associated with pubertal height growth, LIN28B, pleiotropically influences childhood growth, puberty and cancer progression, pointing to shared underlying mechanisms. To discover genetic loci influencing pubertal height and growth and to place them in context of overall growth and maturation, we performed genome-wide association meta-analyses i…

The Molecular Genetic Architecture of Self-Employment

2013

Economic variables such as income, education, and occupation are known to affect mortality and morbidity, such as cardiovascular disease, and have also been shown to be partly heritable. However, very little is known about which genes influence economic variables, although these genes may have both a direct and an indirect effect on health. We report results from the first large-scale collaboration that studies the molecular genetic architecture of an economic variable-entrepreneurship-that was operationalized using self-employment, a widely-available proxy. Our results suggest that common SNPs when considered jointly explain about half of the narrow-sense heritability of self-employment es…

Comparison of the men's and the women's pole vault at the 2000 Sydney Olympic Games

2004

The aim of this study was to identify differences between elite male and female pole vaulters in terms of their mechanical energy and angular momentum. The vaulter's total mechanical energy and angular momentum were calculated from the three-dimensional kinematic data of the pole vault finals at the Sydney 2000 Olympic Games. The development of total, kinetic and potential energy showed similar characteristics for men and women. The initial energy of the vault, the energy at maximum pole bend position and the final energy were significantly higher for male athletes (P0.05), while the energy gain produced by the athletes during the vault showed no significant differences (male vaulters 5.88 …

The role of letter features in visual-word recognition: Evidence from a delayed segment technique.

2016

Available online 9 June 2016 Do all visual features in aword's constituent letters have the same importance during lexical access? Herewe examined whether some components of a word's letters (midsegments, junctions, terminals) are more important than others. To that end,we conducted two lexical decision experiments using a delayed segment techniquewith lowercase stimuli. In this technique a partial previewappears for 50ms and is immediately followed by the target item. In Experiment 1, the partial preview was composed of terminals+junctions,midsegments+junctions, or midsegments + terminals — a whole preview condition was used as a control. Results only revealed an advantage of the whole pre…

Longitudinal heritability of childhood aggression

2016

The genetic and environmental contributions to the variation and longitudinal stability in childhood aggressive behavior were assessed in two large twin cohorts, the Netherlands Twin Register (NTR), and the Twins Early Development Study (TEDS; United Kingdom). In NTR, maternal ratings on aggression from the Child Behavior Checklist (CBCL) were available for 10,765 twin pairs at age 7, for 8,557 twin pairs at age 9/10, and for 7,176 twin pairs at age 12. In TEDS, parental ratings of conduct disorder from the Strength and Difficulty Questionnaire (SDQ) were available for 6,897 twin pairs at age 7, for 3,028 twin pairs at age 9 and for 5,716 twin pairs at age 12. In both studies, stability and…

Quantifying male attractiveness

2003

Genetic models of sexual selection are concerned with a dynamic process in which female preference and male trait values coevolve. We present a rigorous method for characterizing evolutionary endpoints of this process in phenotypic terms. In our phenotypic characterization the mate-choice strategy of female population members determines how attractive females should find each male, and a population is evolutionarily stable if population members are actually behaving in this way. This provides a justification of phenotypic explanations of sexual selection and the insights into sexual selection that they provide. Furthermore, the phenotypic approach also has enormous advantages over a genetic…